Výsledky vyhledávání - "Thierry Verrecchia"

Interactions of poly(lactic acid) and poly(lactic acid-co-ethylene oxide) nanoparticles with the plasma factors of the coagulation system

Autor: Claude Sternberg, Gilles Spenlehauer, Jacqueline Tapon-Bretaudière, Hamid Sahli, Denis Labarre, Thierry Verrecchia, Anne-Marie Fischer

Publikováno v: Biomaterials. 18:281-288

When surfactant-stabilized biodegradable poly(lactic acid) (PLA) particles are injected into rats, the rate of clearance from blood is fast. The rate can be strongly reduced by using particles made from diblock copolymers of PLA and poly(ethylene oxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133afb10b575df3398dd1ecad1a8968f
https://doi.org/10.1016/s0142-9612(96)00146-9

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Effect of PEO surface density on long-circulating PLA-PEO nanoparticles which are very low complement activators

Autor: Didier Bazile, Gilles Spenlehauer, Thierry Verrecchia, Denis Labarre, Francis Puisieux, Michaëlla Vittaz, Michel Veillard

Publikováno v: Biomaterials. 17:1575-1581

The rapid uptake of injected nanoparticles by cells of the mononuclear phagocytes system (MPS) is a major obstacle when a long blood circulation time is needed. Whereas nanoparticles made from PLA and stabilized by surfactants (PLA-F68) are rapidly p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ca9f84699090e8475db6dbfa592ac2
https://doi.org/10.1016/0142-9612(95)00322-3

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Non-stealth (poly(lactic acid/albumin)) and stealth (poly(lactic acid-polyethylene glycol)) nanoparticles as injectable drug carriers

Autor: Y. Archimbaud, Thierry Verrecchia, Didier Bazile, Michel Veillard, A. Murry-Brelier, Gilles Spenlehauer

Publikováno v: Journal of Controlled Release. 36:49-61

Stealth liposomes and, today, stealth nanoparticles, constitute a new generation of parenteral therapeutic systems. PLA/ abumin nanoparticles are of particular interest because they constitute fully biodegradable and well tolerated colloidal suspensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1215131f2947305364570110f63cab97
https://doi.org/10.1016/0168-3659(95)00053-b

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Body distribution of fully biodegradable [14C]-poly(lactic acid) nanoparticles coated with albumin after parenteral administration to rats

Autor: C. Ropert, M. Mariard, A. Frydman, Didier Bazile, Gilles Spenlehauer, Thierry Verrecchia, P. Huve, Michel Veillard

Publikováno v: Biomaterials. 13:1093-1102

Fully biodegradable polylactic acid (PLA) nanoparticles (90–250 nm) coated with human serum albumin (HSA) were prepared by high-pressure emulsification and solvent evaporation, using the protein as surfactant. A new analytical tool was developed, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c0c10127e586d2be7ec69812d3f071
https://doi.org/10.1016/0142-9612(92)90142-b

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Adsorption/desorption of human serum albumin at the surface of poly(lactic acid) nanoparticles prepared by a solvent evaporation process

Autor: Gilles Spenlehauer, P. Huve, Patrick Couvreur, Thierry Verrecchia, Didier Bazile, Michel Veillard

Publikováno v: Journal of biomedical materials research. 27(8)

Biocompatible and biodegradable nanoparticles of poly(lactic acid) (100% L-lactic units = PLA) were prepared by an emulsion, microfluidization, and solvent evaporation method using human serum albumin (HSA) as a surface agent. A radiolabeling techniq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9e818f07af01ba69ecb7d93ac0e7a5
https://pubmed.ncbi.nlm.nih.gov/8408114

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