Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Thierry Umbdenstock"'
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Akademický článek
Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice
Autor: Sabrina Le Bouter, Marianne Rodriguez, Nolwen Guigal-Stephan, Sophie Courtade-Gaïani, Laura Xuereb, Catherine de Montrion, Vincent Croixmarie, Thierry Umbdenstock, Claire Boursier-Neyret, Michel Lonchampt, Manuel Brun, Catherine Dacquet, Alain Ktorza, Brian-Paul Lockhart, Jean-Pierre Galizzi
Publikováno v: PPAR Research, Vol 2010 (2010)
Rosiglitazone (RSG), developed for the treatment of type 2 diabetes mellitus, is known to have potent effects on carbohydrate and lipid metabolism leading to the improvement of insulin sensitivity in target tissues. To further assess the capacity of
Externí odkaz: https://doaj.org/article/46df16f6182e4c53869defeac3035f9f
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3
On-tissue chemical derivatization reagents for matrix-assisted laser desorption/ionization mass spectrometry imaging
Autor: Mélanie Lagarrigue, Charles Pineau, Mira Merdas, Georges Da Violante, Thierry Umbdenstock, Quentin P. Vanbellingen
Publikováno v: Journal of Mass Spectrometry
Journal of Mass Spectrometry, Wiley-Blackwell, In press, ⟨10.1002/jms.4731⟩
Journal of Mass Spectrometry, 2021, 56 (10), ⟨10.1002/jms.4731⟩
International audience; Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a key tool for the analysis of biological tissues. It provides spatial and quantitative information about different types of analytes within
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75b879d06609230d0bd48f60c871ab4
https://hal.archives-ouvertes.fr/hal-03268385/document
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6
Mass Spectrometry-Based Metabolomics: Accelerating the Characterization of Discriminating Signals by Combining Statistical Correlations and Ultrahigh Resolution
Autor: Pierre Chaminade, Eric Ezan, Thierry Umbdenstock, Vincent Croixmarie, Jean-Claude Tabet, Christophe Junot, Erwan Werner
Publikováno v: Analytical Chemistry. 80:4918-4932
A strategy combining autocorrelation matrices and ultrahigh resolution mass spectrometry (MS) was developed to optimize the characterization of discriminating ions highlighted by metabolomics. As an example, urine samples from rats treated with pheno
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7ab93c09970cfaf3c9284c9d5b6241
https://doi.org/10.1021/ac800094p
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7
UPLC–MS retention time prediction: a machine learning approach to metabolite identification in untargeted profiling
Autor: Thierry Umbdenstock, Alban Arrault, Arnaud M. Wolfer, Philippe Vayer, Vincent Croixmarie, Sylvain Lozano
Publikováno v: Metabolomics. 12
Metabolic profiling focuses on the analysis of a wide range of small endogenous molecules in order to understand the response of a living system to perturbations. Ultra high performance liquid chromatography–mass spectrometry is a widely employed p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4158d270dfe004f420f4a119a6ea540d
https://doi.org/10.1007/s11306-015-0888-2
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8
PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells
Autor: Thierry Umbdenstock, Alexandra Rogue, Catherine de la Moureyre-Spire, Sébastien Anthérieu, Aurore Vluggens, Richard J. Weaver, Nancy Claude, André Guillouzo
Publikováno v: Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology, 2014, 276 (1), pp.73-81. ⟨10.1016/j.taap.2014.02.001⟩
Toxicology and Applied Pharmacology, Elsevier, 2014, 276 (1), pp.73-81. ⟨10.1016/j.taap.2014.02.001⟩
International audience; Although non-alcoholic fatty liver disease (NAFLD) is currently the most common form of chronic liver disease there is no pharmacological agent approved for its treatment. Since peroxisome proliferator-activated receptors (PPA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b0e8efa9a52b8dfcf095333bd6e08e
https://univ-rennes.hal.science/hal-01020611/document
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9
Metabonomic studies on human hepatocyte in primary culture
Autor: Vincent, Croixmarie, Thierry, Umbdenstock, Olivier, Cloarec, Amélie, Moreau, Jean-Marc, Pascussi, Yannick, Parmentier, Claire, Boursier-Neyret, Bernard, Walther
Publikováno v: Methods in molecular biology (Clifton, N.J.). 640
Mechanisms involved in induction processes have been investigated using fresh human hepatocytes in culture as a cellular model and using mass spectrometry-based metabonomics as a global investigation tool. Sample preparation to data analysis have bee
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4052c5e5142ded0fb5f2d03ad693a3cc
https://pubmed.ncbi.nlm.nih.gov/20645062
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10
Metabonomic Studies on Human Hepatocyte in Primary Culture
Autor: Claire Boursier-Neyret, Vincent Croixmarie, Olivier Cloarec, Bernard Walther, Yannick Parmentier, Jean-Marc Pascussi, Amélie Moreau, Thierry Umbdenstock
Publikováno v: Methods in Molecular Biology ISBN: 9781607616870
Mechanisms involved in induction processes have been investigated using fresh human hepatocytes in culture as a cellular model and using mass spectrometry-based metabonomics as a global investigation tool. Sample preparation to data analysis have bee
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8de9688fa08753dbc31bfa430803fd4
https://doi.org/10.1007/978-1-60761-688-7_19
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