Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thierry Tchénio"'
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2017, 107, pp.266-277. ⟨10.1016/j.freeradbiomed.2016.11.040⟩
Free Radical Biology and Medicine, Elsevier, 2017, 107, pp.266-277. ⟨10.1016/j.freeradbiomed.2016.11.040⟩
In cellular organisms composition of DNA is constrained to only four nucleobases A, G, T and C, except for minor DNA base modifications such as methylation which serves for defence against foreign DNA or gene expression regulation. Interestingly, thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cf22be0ed8463a23725cd18eae6586
https://doi.org/10.1016/j.freeradbiomed.2016.11.040
https://doi.org/10.1016/j.freeradbiomed.2016.11.040
Autor:
Anh Thu Bui, Thierry Tchénio, François Dautry, Maryline Havard, Meng-Er Huang, Fanny Laurent-Tchenio
Cellular quiescence is a reversible cell growth arrest that is often assumed to require a persistence of non-permissive external growth conditions for its maintenance. In this work, we showed that androgen could induce a quiescent state that is self-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b18d6ba3bc45a897abd6a264fb8e632
https://europepmc.org/articles/PMC5444360/
https://europepmc.org/articles/PMC5444360/
Publikováno v:
Journal of Biological Chemistry. 286:44177-44186
Cell dormancy constitutes a limiting step of the metastatic process by preventing the proliferation of isolated cancer cells disseminated at distant sites from the primary tumor. The study of cancer cell dormancy is severely hampered by the lack of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d683449c6ca0c31ec5e6327afcb80342
https://doi.org/10.1074/jbc.m111.262709
https://doi.org/10.1074/jbc.m111.262709
Autor:
Irina Naguibneva, Thierry Tchénio, Annick Harel-Bellan, Arlette Vervisch, Luis Martinez, Heike Lehrmann, Guillermina Lozano
Publikováno v:
Proceedings of the National Academy of Sciences. 99:14849-14854
Single base pair mutations that alter the function of tumor suppressor genes and oncogenes occur frequently during oncogenesis. The guardian of the genome, p53, is inactivated by point mutation in more than 50% of human cancers. Synthetic small inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f779936b1b57411cda3a90a17dde272
https://doi.org/10.1073/pnas.222406899
https://doi.org/10.1073/pnas.222406899
Autor:
Thierry Tchénio
Publikováno v:
Tumor Dormancy, Quiescence, and Senescence, Volume 1 ISBN: 9789400759572
The metastatic disease determines the cancer-specific death of most patients suggesting that decreasing the rate of metastasis should translate into increased cancer-specific survival. Several experiments in mice suggest that a major limiting step of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c51b836cd6f4eb7dea0ba99bf32979f2
https://doi.org/10.1007/978-94-007-5958-9_5
https://doi.org/10.1007/978-94-007-5958-9_5
Publikováno v:
Europe PubMed Central
ResearcherID
ResearcherID
Using as a reporter gene a non-coding proviral structure marked with an intron-containing indicator, we demonstrate the de novo formation, via a retrotransposition pathway, of canonical processed pseudogenes in cultured mammalian cells. Their structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa5b7725fdf5c8650a303d4fdd92fda
https://doi.org/10.1002/j.1460-2075.1993.tb05792.x
https://doi.org/10.1002/j.1460-2075.1993.tb05792.x
Publikováno v:
Molecular and cellular biology. 26(2)
The screening of two different retroviral cDNA expression libraries to select genes that confer constitutive doxorubicin resistance has in both cases resulted in the isolation of the heat shock factor 1 (HSF1) transcription factor. We show that HSF1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9dd2c5f4260f67c2f08bbb3ef0532aa
https://pubmed.ncbi.nlm.nih.gov/16382149
https://pubmed.ncbi.nlm.nih.gov/16382149
Chromatin assembly factor 1 (CAF-1) is a protein complex formed of three subunits, p150, p60, and p48, conserved from the yeast Saccharomyces cerevisiae to humans, which can promote nucleosome assembly onto newly replicated DNA. In S. cerevisiae, del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be86596c6c02f24f0b2ce4d8f66702be
https://europepmc.org/articles/PMC86785/
https://europepmc.org/articles/PMC86785/
LINEs are endogenous mobile genetic elements which have dispersed and accumulated in the genomes of most higher eukaryotes via germline transposition, with up to 100 000 copies for the human LINE-1 (L1H) sequences. Although severely repressed in most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348a874e2dae2ea65d99b3499bc70d61
https://europepmc.org/articles/PMC102531/
https://europepmc.org/articles/PMC102531/
Publikováno v:
Virology. :28-38
Xenotropic Murine leukemia virus-Related Virus (XMRV) directly arose from genetic recombinations between two endogenous murine retroviruses that occurred during human xenografts in laboratory mice. Studies on XMRV could thus bring clues on how a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e0fbb7c4defd93cb2df954a3086cc6