Segmenting Proteins into Tripeptides to Enhance Conformational Sampling with Monte Carlo Methods

Autor: Laurent Denarie, Ibrahim Al-Bluwi, Marc Vaisset, Thierry Siméon, Juan Cortés

Publikováno v: Molecules, Vol 23, Iss 2, p 373 (2018)

This paper presents an approach to enhance conformational sampling of proteins employing stochastic algorithms such as Monte Carlo (MC) methods. The approach is based on a mechanistic representation of proteins and on the application of methods origi

Externí odkaz: https://doaj.org/article/793453063d444fcfb91d238c6d87075a

THUMB-LOOPS UP FOR CATALYSIS: A STRUCTURE/FUNCTION INVESTIGATION OF A FUNCTIONAL LOOP MOVEMENT IN A GH11 XYLANASE

Autor: Gabriel Paës, Juan Cortés, Thierry Siméon, Michael J. O'Donohue, Vinh Tran

Publikováno v: Computational and Structural Biotechnology Journal, Vol 1, Iss 2 (2012)

Dynamics is a key feature of enzyme catalysis. Unfortunately, current experimental and computational techniques do not yet provide a comprehensive understanding and description of functional macromolecular motions. In this work, we have extended a no

Externí odkaz: https://doaj.org/article/88978de788d2407299b9ebd7a9ec2ade

Children's mental and behavioral health, schooling, and socioeconomic characteristics during school closure in France due to COVID-19: the SAPRIS project

Autor: Marie-Aline Charles, Cédric Galéra, Sabine Plancoulaine, Thierry Siméon, Maëva Monnier, Stéphanie Vandentorren, Bertrand Geay, Maria Melchior, Laetitia Marchand, Bruno Falissard, Pierre-Yves Ancel, Susana Barbosa, Sylvana M. Côté, Flore Moulin, Alexandra Rouquette, Xavier Thierry

Publikováno v: Scientific Reports
Scientific Reports, 2021, 11 (1), pp.22373. ⟨10.1038/s41598-021-01676-7⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-01676-7⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

COVID-19 limitation strategies have led to widespread school closures around the world. The present study reports children’s mental health and associated factors during the COVID-19 school closure in France in the spring of 2020. We conducted a cro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd807bd6a09c3e6d74d1013d389b501
https://hal.sorbonne-universite.fr/hal-03443056

Les enfants à l’épreuve du premier confinement

Autor: Ariane Pailhé, Jean-Louis Lanoë, Sylvie Octobre, Nicolas Cauchi-Duval, Nathalie Berthomier, Jérôme Camus, Xavier Thierry, Julie Pagis, Anne Solaz, Sapris, Lidia Panico, Thierry Siméon, Bertrand Geay

Publikováno v: Population et sociétés
Population et sociétés, INED, 2021, N°585 (1), pp.1. ⟨10.3917/popsoc.585.0001⟩
Population et sociétés, INED, 2021, ⟨10.3917/popsoc.585.0001⟩
Population et sociétés, 2021, N°585 (585), pp.1. ⟨10.3917/popsoc.585.0001⟩

During the first COVID-19 lockdown in France in the spring of 2020, schools were closed and all activities outside the home were suspended. Primary school children who found themselves confined to their homes adapted quite well to the change. They co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2115da3d89a879f00e8fcd77ae11b5e
https://hal.archives-ouvertes.fr/hal-03415513

Social patterning of childhood overweight in the French national ELFE cohort

Autor: Camille Le Gal, Marion Lecorguillé, Lorraine Poncet, Aminata Hallimat Cissé, Malamine Gassama, Thierry Simeon, Jean-Louis Lanoë, Maria Melchior, Jonathan Y. Bernard, Marie-Aline Charles, Barbara Heude, Sandrine Lioret

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Abstract An inverse social gradient in early childhood overweight has been consistently described in high-income countries; however, less is known about the role of migration status. We studied the social patterning of overweight in preschool childre

Externí odkaz: https://doaj.org/article/db20e041bbc34395a688aedf9634e9f8