Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Thierry Pécot"'
Autor:
Theo Guitton, Pierre Allaume, Noémie Rabilloud, Nathalie Rioux-Leclercq, Sébastien Henno, Bruno Turlin, Marie-Dominique Galibert-Anne, Astrid Lièvre, Alexandra Lespagnol, Thierry Pécot, Solène-Florence Kammerer-Jacquet
Publikováno v:
Diagnostics, Vol 14, Iss 1, p 99 (2023)
Mismatch repair deficiency (d-MMR)/microsatellite instability (MSI), KRAS, and BRAF mutational status are crucial for treating advanced colorectal cancer patients. Traditional methods like immunohistochemistry or polymerase chain reaction (PCR) can b
Externí odkaz:
https://doaj.org/article/ab2a4a0f2d7c4d5bbc3313fcf2072155
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009949 (2022)
Automatic characterization of fluorescent labeling in intact mammalian tissues remains a challenge due to the lack of quantifying techniques capable of segregating densely packed nuclei and intricate tissue patterns. Here, we describe a powerful deep
Externí odkaz:
https://doaj.org/article/5044be5b25b447c88f08881c256a3156
Publikováno v:
F1000Research, Vol 10 (2022)
Deep learning has revolutionized the automatic processing of images. While deep convolutional neural networks have demonstrated astonishing segmentation results for many biological objects acquired with microscopy, this technology's good performance
Externí odkaz:
https://doaj.org/article/861f3750609a4b48ab49b3032fcfa20e
Autor:
Maria C. Cuitiño, Thierry Pécot, Daokun Sun, Raleigh Kladney, Takayuki Okano-Uchida, Neelam Shinde, Resham Saeed, Antonio J. Perez-Castro, Amy Webb, Tom Liu, Soo In Bae, Linda Clijsters, Nicholas Selner, Vincenzo Coppola, Cynthia Timmers, Michael C. Ostrowski, Michele Pagano, Gustavo Leone
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3547-3560.e5 (2019)
Summary: Orchestrating cell-cycle-dependent mRNA oscillations is critical to cell proliferation in multicellular organisms. Even though our understanding of cell-cycle-regulated transcription has improved significantly over the last three decades, th
Externí odkaz:
https://doaj.org/article/c31ffe76ede44013852e8706ff9e9160
Publikováno v:
eLife, Vol 7 (2018)
Analysis of the spatial distribution of endomembrane trafficking is fundamental to understand the mechanisms controlling cellular dynamics, cell homeostasy, and cell interaction with its external environment in normal and pathological situations. We
Externí odkaz:
https://doaj.org/article/5465b74822e14d268cfddde960da1158
Autor:
Michael C. Ostrowski, Blake E. Hildreth, Gustavo W. Leone, Morag Park, Michael Hallett, Lianbo Yu, Soledad A. Fernandez, Shan K. Naidu, Gina M. Sizemore, Thierry Pécot, Anthony J. Trimboli, Julie A. Wallace Reeser, Xin Liu, Jinghai Wu
Supplementary Data from Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2308e3a914ef71eb9e9d9ab883f67a57
https://doi.org/10.1158/1541-7786.22527600.v1
https://doi.org/10.1158/1541-7786.22527600.v1
Autor:
Manon Lesage, Manon Thomas, Thierry Pécot, Tu-Ky Ly, Nathalie Hinfray, Remy Beaudouin, Michelle Neumann, Robin Lovell-Badge, Jérôme Bugeon, Violette Thermes
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), 2023, 150 (7), pp.dev201185. ⟨10.1242/dev.201185⟩
Development (Cambridge, England), 2023, 150 (7), pp.dev201185. ⟨10.1242/dev.201185⟩
Computational analysis of bio-images by deep learning (DL) algorithms has made exceptional progress in recent years and has become much more accessible to non-specialists with the development of ready-to-use tools. The study of oogenesis mechanisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4fc1ef9484e7da918f1f295b7e0cbdc
https://hal.science/hal-04062159
https://hal.science/hal-04062159
Autor:
Juliette Ferrant, Simon Le Gallou, Francine Padonou, Simon Léonard, Ilénia Papa, Céline Pangault, Anne Barthel, Vincent Launay, Guillaume Manson, Bénédicte Hoareau, Laurent Deleurme, Céline Monvoisin, Benoit Albaud, Nathalie Van Acker, Camille Laurent, Francisco Llamas-Gutierrez, Henri-Alexandre Michaud, Nathalie Bonnefoy, Thierry Pécot, Karin Tarte, Mikael Roussel
SummaryDiffuse large B cell lymphoma (DLBCL) and follicular lymphoma (FL) are the two most common B-cell lymphomas and are characterized by a dynamic crosstalk between tumor B cells and a heterogeneous tumor-supportive microenvironment, including imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe5d920778e5b9cf5366d5cd378beb1
https://doi.org/10.1101/2022.12.08.519637
https://doi.org/10.1101/2022.12.08.519637
Computational analysis of bio-images by deep learning (DL) algorithms has made exceptional progress in recent years and has become much more accessible to non-specialists with the development of ready-to-use tools. The study of oogenesis mechanisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ffc83f7ef9c1cf51f2d4725801a79e
https://hal.science/hal-03759490/document
https://hal.science/hal-03759490/document
Autor:
Michael C. Ostrowski, Catherine MarElia-Bennet, Cynthia J. Timmers, Akiko Koide, John P. O'Bryan, Mariyam Zuberi, Julia E. Lefler, Thierry Pécot, Eric Denbaum, Dean M. Connor, Imran Khan, Ann-Marie Broome, Shohei Koide
Publikováno v:
Small GTPases
RAS is the most frequently mutated oncogene in human cancer with nearly ~20% of cancer patients possessing mutations in one of three RAS genes (K, N or HRAS). However, KRAS is mutated in nearly 90% of pancreatic ductal carcinomas (PDAC). Although pha