Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Thierry Massfelder"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/e840139ff2e44a4db19000df112efa6a
Autor:
Claire Béraud, Nadege Bidan, Myriam Lassalle, Hervé Lang, Véronique Lindner, Clémentine Krucker, Julien Masliah-Planchon, Eric Potiron, Philippe Lluel, Thierry Massfelder, Yves Allory, Yolande Misseri
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundDespite the significant advances in the management of advanced prostate cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in precision treatment, the development of preclinical models representing th
Externí odkaz:
https://doaj.org/article/b98cdf9241d943d58e20b5feeffc4c38
Autor:
Hervé Lang, Claire Béraud, Luc Cabel, Jacqueline Fontugne, Myriam Lassalle, Clémentine Krucker, Florent Dufour, Clarice S. Groeneveld, Victoria Dixon, Xiangyu Meng, Aurélie Kamoun, Elodie Chapeaublanc, Aurélien De Reynies, Xavier Gamé, Pascal Rischmann, Ivan Bieche, Julien Masliah-Planchon, Romane Beaurepere, Yves Allory, Véronique Lindner, Yolande Misseri, François Radvanyi, Philippe Lluel, Isabelle Bernard-Pierrot, Thierry Massfelder
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMuscle-invasive bladder cancer (MIBC) and upper urinary tract urothelial carcinoma (UTUC) are molecularly heterogeneous. Despite chemotherapies, immunotherapies, or anti-fibroblast growth factor receptor (FGFR) treatments, these tumors are
Externí odkaz:
https://doaj.org/article/530d7616638a4e26a742ecd5e89e062d
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/dd63d429121944db8cf6900eb7d20452
Autor:
Ezeddine Harmouch, Joseph Seitlinger, Hassan Chaddad, Geneviève Ubeaud-Sequier, Jochen Barths, Sani Saidu, Laurent Désaubry, Stéphanie Grandemange, Thierry Massfelder, Guy Fuhrmann, Florence Fioretti, Monique Dontenwill, Nadia Benkirane-Jessel, Ysia Idoux-Gillet
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Glioblastoma (GBM) is one of the most aggressive types of cancer, which begins within the brain. It is the most invasive type of glioma developed from astrocytes. Until today, Temozolomide (TMZ) is the only standard chemotherapy for patients
Externí odkaz:
https://doaj.org/article/b7f71d227f1e45b69f1e97f821dc7517
Autor:
Natacha Rochel, Clémentine Krucker, Laure Coutos-Thévenot, Judit Osz, Ruiyun Zhang, Elodie Guyon, Wayne Zita, Séverin Vanthong, Oscar Alba Hernandez, Maxime Bourguet, Kays Al Badawy, Florent Dufour, Carole Peluso-Iltis, Syrine Heckler-Beji, Annick Dejaegere, Aurélie Kamoun, Aurélien de Reyniès, Yann Neuzillet, Sandra Rebouissou, Claire Béraud, Hervé Lang, Thierry Massfelder, Yves Allory, Sarah Cianférani, Roland H. Stote, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Activation of the PPARγ/RXRα pathway in luminal bladder cancers has mainly been linked to PPARG gene amplifications and activating point mutations in RXRα. Here, the authors identify recurrent PPARγ mutations with similar effects and elucidate th
Externí odkaz:
https://doaj.org/article/5e44a383003c4ce0b87b4a701664d7c3
Autor:
Mélanie Mahe, Florent Dufour, Hélène Neyret‐Kahn, Aura Moreno‐Vega, Claire Beraud, Mingjun Shi, Imene Hamaidi, Virginia Sanchez‐Quiles, Clementine Krucker, Marion Dorland‐Galliot, Elodie Chapeaublanc, Remy Nicolle, Hervé Lang, Celio Pouponnot, Thierry Massfelder, François Radvanyi, Isabelle Bernard‐Pierrot
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 4, Pp n/a-n/a (2018)
Abstract FGFR3 alterations (mutations or translocation) are among the most frequent genetic events in bladder carcinoma. They lead to an aberrant activation of FGFR3 signaling, conferring an oncogenic dependence, which we studied here. We discovered
Externí odkaz:
https://doaj.org/article/1ed43450adb6412f8cc0a5fba9c79f14
Autor:
Thierry Massfelder, Hervé Lang, Jean-Jacques Helwig, Didier Jacqmin, Nicolas Meyer, Sylvie Rothhut, Jacques Steger, Véronique Lindner, Sabrina Danilin, Carole Sourbier
Metastatic renal cell carcinoma (RCC) remains refractory to therapies. The nuclear factor-κB (NF-κB) transcription factor is involved in cell growth, cell motility, and vascularization. We evaluated whether targeting NF-κB could be of therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a0710cb2d897a379334fe1bf1ba381f
https://doi.org/10.1158/0008-5472.c.6496715
https://doi.org/10.1158/0008-5472.c.6496715
Autor:
Thierry Massfelder, Hervé Lang, Jean-Jacques Helwig, Didier Jacqmin, Nicolas Meyer, Sylvie Rothhut, Jacques Steger, Véronique Lindner, Sabrina Danilin, Carole Sourbier
Supplementary Legends 1-6 from Targeting the Nuclear Factor-κB Rescue Pathway Has Promising Future in Human Renal Cell Carcinoma Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b8e70f6dc7a98468cbd9637236d24b
https://doi.org/10.1158/0008-5472.22371245.v1
https://doi.org/10.1158/0008-5472.22371245.v1
Autor:
Thierry Massfelder, Hervé Lang, Jean-Jacques Helwig, Didier Jacqmin, Nicolas Meyer, Sylvie Rothhut, Jacques Steger, Véronique Lindner, Sabrina Danilin, Carole Sourbier
Supplementary Figure 4 from Targeting the Nuclear Factor-κB Rescue Pathway Has Promising Future in Human Renal Cell Carcinoma Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2180652c6775dd4d9a734b92536ccd05
https://doi.org/10.1158/0008-5472.22371254
https://doi.org/10.1158/0008-5472.22371254