Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Thierry Marie Jahan"'
Autor:
Erica S Tsang, Rahul Raj Aggarwal, Scott Thomas, Mallika Sachdev Dhawan, Nela Pawlowska, Imke Heleen Bartelink, Jennifer A. Grabowsky, Thierry Marie Jahan, Thach-Giao Truong, Charles J. Ryan, Pamela N. Munster
Publikováno v:
Journal of Clinical Oncology. 40:3150-3150
3150 Background: Histone deacetylase (HDAC) inhibition downregulates HIF-1a, which may be effective in overcoming resistance to VEGF-targeting tyrosine kinase inhibitors. We report the updated survival follow-up for patients treated with abexinostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e34eb5a7ed4a3445841c9edc5556be3b
https://doi.org/10.1200/jco.2022.40.16_suppl.3150
https://doi.org/10.1200/jco.2022.40.16_suppl.3150
Autor:
Rahul Raj Aggarwal, Jennifer A. Grabowsky, Anne Reinert, Scott Thomas, Paromita Raha, Thierry Marie Jahan, Alain Patrick Algazi, Terence W. Friedlander, Thach-Giao Truong, Saloni Mathur, Pamela N. Munster
Publikováno v:
Journal of Clinical Oncology. 32:2577-2577
2560 Background: PAZ is a tyrosine kinase inhibitor of VEGFR, PDGFR, and C-KIT approved for use in renal cell carcinoma (RCC) and soft tissue sarcoma (STS). ABX is a potent pan-HDAC inhibitor (HDAC...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b28af14f9bb382bebadb00ff4deb9c93
https://doi.org/10.1200/jco.2014.32.15_suppl.2577
https://doi.org/10.1200/jco.2014.32.15_suppl.2577
Autor:
Amy Patricia Moore, Thach-Giao Truong, Kenneth Ted Thurn, Scott Thomas, Charles J. Ryan, Thierry Marie Jahan, Steven G. DuBois, John K. Chan, Hope S. Rugo, Eric Andrew Collisson, Paromita Raha, Stephanie Chen, Anne Reinert, Adil Daud, Pamela N. Munster
Publikováno v:
Journal of Clinical Oncology. 30:3058-3058
3058 Background: Preclinical and clinical data suggest pre-exposure of cancer cells to a histone deacetylase inhibitor (HDACi) potentiates topoisomerase inhibitors. HDACi-induced histone acetylation and chromatin modulation facilitates DNA access and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3faba629ecca0cfa87a97398bf35cae0
https://doi.org/10.1200/jco.2012.30.15_suppl.3058
https://doi.org/10.1200/jco.2012.30.15_suppl.3058