Zobrazeno 1 - 10
of 629
pro vyhledávání: '"Thierry LECOMTE"'
Autor:
Thibault Mazard, Caroline Mollevi, Evelyne M. Loyer, Julie Léger, Romain Chautard, Olivier Bouché, Christophe Borg, Paul Armand-Dujardin, Aurore Bleuzen, Eric Assenat, Thierry Lecomte
Publikováno v:
Cancer Imaging, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background The Response Evaluation Criteria in Solid Tumors (RECIST) are often inadequate for the early assessment of the response to cancer therapy, particularly bevacizumab-based chemotherapy. In a first cohort of patients with colorectal
Externí odkaz:
https://doaj.org/article/d45f0dda6e3d4238af2a749c58b51981
Autor:
Alison Robert, David Crottès, Jérôme Bourgeais, Naig Gueguen, Arnaud Chevrollier, Jean-François Dumas, Stéphane Servais, Isabelle Domingo, Stéphanie Chadet, Julien Sobilo, Olivier Hérault, Thierry Lecomte, Christophe Vandier, William Raoul, Maxime Guéguinou
Publikováno v:
PLoS Biology, Vol 22, Iss 10, p e3002854 (2024)
The mitochondrial Ca2+ uniporter (MCU) plays crucial role in intramitochondrial Ca2+ uptake, allowing Ca2+-dependent activation of oxidative metabolism. In recent decades, the role of MCU pore-forming proteins has been highlighted in cancer. However,
Externí odkaz:
https://doaj.org/article/d921cf1a11eb48efbb81622c970372c0
Autor:
Koen Zwart, Frederieke H. van derBaan, Romain Cohen, Thomas Aparicio, Christelle de laFouchardiére, Thierry Lecomte, Cornelis J. A. Punt, David Sefrioui, Rik J. Verheijden, Geraldine R. Vink, G. Emerens Wensink, Aziz Zaanan, Miriam Koopman, David Tougeron, Jeanine M. L. Roodhart
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 15841-15853 (2023)
Abstract Background Current knowledge on prognostic biomarkers (especially BRAFV600E/RAS mutations) in metastatic colorectal cancer (mCRC) is mainly based on mCRC patients with proficient mismatch repair (pMMR) tumors. It is uncertain whether these b
Externí odkaz:
https://doaj.org/article/78172ed8afd94d10ab4cb901ea49fe41
Autor:
Sylvain Manfredi, Marie Dior, Olivier Bouche, Emilie Barbier, Vincent Hautefeuille, Marielle Guillet, Justine Turpin, Vincent Bourgeois, Dall Osto Helene, Romain Desgrippes, Franck Audemar, Yann Molin, Christophe Locher, Thierry Chatellier, Thierry Lecomte, Nathalie Baize, Cedric Lecaille, Dominique Spaeth, Gael Goujon, Come Lepage, David Tougeron, For The Metestomac Investigators/Collaborators
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5341-5351 (2023)
Abstract Background Around 50% of gastric cancers are diagnosed at an advanced stage. Several chemotherapy regimens are now internationally validated. Few data are available on the routine daily management of advanced gastric or gastroesophageal junc
Externí odkaz:
https://doaj.org/article/c63cf54191d040b09637705899990774
Autor:
Adeline Dolly, Thierry Lecomte, Nicolas Tabchouri, Morgane Caulet, Nicolas Michot, Benjamin Anon, Romain Chautard, Yoann Desvignes, Mehdi Ouaissi, Gaëlle Fromont‐Hankard, Jean‐François Dumas, Stéphane Servais
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1837-1849 (2022)
Abstract Background Cancer cachexia is a multifactorial syndrome characterized by involuntary and pathological weight loss, mainly due to skeletal muscle wasting, resulting in a decrease in patients' quality of life, response to cancer treatments, an
Externí odkaz:
https://doaj.org/article/6a68b874a41c439bb8a225535c7618c3
Autor:
Elias Karam, Petru Bucur, Camille Gil, Remy Sindayigaya, Nicolas Tabchouri, Louise Barbier, Urs Pabst-Giger, Pascal Bourlier, Thierry Lecomte, Driffa Moussata, Sophie Chapet, Gilles Calais, Mehdi Ouaissi, Ephrem Salamé
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Colorectal cancer is the third most common cancer in France and by the time of the diagnosis, 15–25% of patients will suffer from synchronous liver metastases. Surgery associated to neoadjuvant treatment can cure these patients,
Externí odkaz:
https://doaj.org/article/104d804745d0431aa2be0c4ad7739a1e
Autor:
Axelle Rivière, Anne Isabelle Lecuyer, Emeline Laurent, Carole Lefebvre, Thierry Lecomte, Elodie Olivier, Delphine Carmier, Laurent Plantier, Leslie Grammatico-Guillon
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Background It is unclear whether delays in care affect prognosis of patients with lung cancer. The primary objective of this study was to describe the care pathway of patients diagnosed with lung cancer in a French region. Secondary objectives were t
Externí odkaz:
https://doaj.org/article/6a93b7a3dce441c3a4e7d1994ec99287
Autor:
Vittoria Balzano, Emeline Laurent, Aline-Marie Florence, Anne-Isabelle Lecuyer, Carole Lefebvre, Patrick Heitzmann, Pascal Hammel, Thierry Lecomte, Leslie Grammatico-Guillon
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Excessive waiting time intervals for the diagnosis and treatment of patients with pancreatic cancer can influence their prognosis but they remain unclear. The objective was to describe time intervals from the medical visit to diagnostic i
Externí odkaz:
https://doaj.org/article/b7bba80a33cf4115b43c910593ec7ef2
Autor:
Alice Artus, Nicolas Tabchouri, Othman Iskander, Nicolas Michot, Olivier Muller, Urs Giger-Pabst, Pascal Bourlier, Céline Bourbao-Tournois, Aurore Kraemer-Bucur, Thierry Lecomte, Ephrem Salamé, Mehdi Ouaissi
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The influence of anastomotic leakage (AL) on local recurrence rates and survival in rectal cancer remains controversial. The aim of this study was to analyze the effect of asymptomatic anastomotic leakage (AAL) and symptomatic ana
Externí odkaz:
https://doaj.org/article/5d7c1c6125b64b489ac4d81dc2a77972
Autor:
Thomas Couronne, Paul Girot, Julien Hadoux, Thierry Lecomte, Alice Durand, Caroline Fine, Katia Vandevoorde, Catherine Lombard-Bohas, Thomas Walter
Publikováno v:
Endocrine Connections, Vol 9, Iss 6, Pp 498-505 (2020)
Objective: First-line chemotherapy in metastatic neuroendocrine carcinomas (NECs) is based on etoposide and platinum. However, there is no standard concerning second-line treatment. The objective of this study was to evaluate effic acy and tolerance
Externí odkaz:
https://doaj.org/article/86851713c3d2448bb59ddd470a1a72ef