Manufacturing Execution Systems: Examples of Performance Indicator and Operational Robustness Tools

Autor: Jean-François Demuth, Myrtille Guyon, Yannick Gendre, Thierry Humbert, Gérard Waridel, Hervé Guelpa

Publikováno v: CHIMIA, Vol 70, Iss 9 (2016)

Manufacturing Execution Systems (MES) are computerized systems used to measure production performance in terms of productivity, yield, and quality. In the first part, performance indicator and overall equipment effectiveness (OEE), process robustness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4325a841368253df3b1ea3ae939025fa
https://pubmed.ncbi.nlm.nih.gov/27646542

Solid phase synthesis of a tetrapeptide labelled with Carbon-13. Preparation of L-[U-13C]lysyl-L-[1-13C]arginyl-L-[3-13C]asparyl-L-[1-13C]serine

Autor: Cuong Luu-Duc, Alain Marsura, Thierry Humbert

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 31:183-198

Synthesis of a [13C] tetrapeptide L-[U-13C]Lysyl-L-[1-13C]Arginyl-L-[3-13C]Aspartyl-L-[1-13C] Serine (KRDS) on a p-alkoxybenzyl ester polystyrene-1% divinylbenzene resin support is described by using repetitive nonhydrolytic base cleavage of α-amino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fed7f5947ff89f9551fe1800c6f6ee2
https://doi.org/10.1002/jlcr.2580310304

Heptakis-6-(5-methylene-ureido-5′-methyl-2,2′-bipyridinyl)-cyclomaltoheptaose as a new fluorescent lanthanide polydentate ligand

Autor: F. Charbonnier, Alain Marsura, Thierry Humbert

Publikováno v: Tetrahedron Letters
Tetrahedron Letters, Elsevier, 1999, 40 (21), pp.4047-4050. ⟨10.1016/S0040-4039(99)00668-1⟩

The present work describes the one-pot synthesis of an heptakis-(bipyridinyl-ureido)-β-cyclodextrin in a high coupling average (82%) by the “phosphinimine” approach. The subsequent complexation of 3 with EuCl 3 or TbCl 3 gives stable complexes 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c3c0796796e9c4307bfdaed0ffc065
https://hal.archives-ouvertes.fr/hal-02193839

Heterogeneous distribution of a fatty acid analogue uptake in the myocardium of aged rats

Autor: Pierre Demenge, Thierry Humbert, Jean Verdetti, Colette Estrade, Catherine Communal

Publikováno v: Canadian journal of physiology and pharmacology. 72(10)

The aim of this study was to determine the extent and location of damaged myocardial areas in senescent rats. The viability of myocardial cells was evaluated in virgin young (4 months old) and aged (29 months old) female Wistar rats by analysing the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58646ed1bb019761b1343a51780ca32d
https://pubmed.ncbi.nlm.nih.gov/7882175

Influence of the presence of a methyl group on the myocardial metabolism of 15-(paraiodophenyl)-3 methyl pentadecanoic acid (IMPPA)

Autor: Xavier Leverve, Thierry Humbert, Danièle Marti Batlle, Pierre Cuchet, Christiane Keriel, M. Comet, Cuong Luu-Duc

Publikováno v: International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1990, 17 (8), pp.745-9
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, Elsevier, 1990, 17 (8), pp.745-9

International audience; The objective of the present study was to determine the mechanism of accumulation of myocardial activity following i.v. injection of 15-(paraiodophenyl)-3 methyl pentadecanoic acid (IMPPA). IMPPA and 15 phenyl-3 methyl pentade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30005fffa947e68cd4634f06e473856
https://www.hal.inserm.fr/inserm-00390276