Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thierry Frappier"'
Publikováno v:
Journal of Neurochemistry. 63:2288-2294
Tau proteins are microtubule-associated proteins that promote microtubule polymerization in vitro and in vivo. They are a family of neuronal proteins with apparent molecular weights in the range 50,000-68,000 determined by sodium dodecyl sulfate-poly
Publikováno v:
Journal of Neurochemistry. 70:540-549
Peripherin is a type III intermediate filament present in peripheral and certain CNS neurons. We report here that peripherin contains a phosphotyrosine residue and, as such, is the only identified intermediate filament protein known to be modified in
Publikováno v:
Scopus-Elsevier
Ankyrins are a multi-gene family of peripheral proteins that link ion channels and cell adhesion molecules to the spectrin-based skeleton in specialized membrane domains. In the mammalian skeletal myofiber, ankyrins were immunolocalized in several me
Autor:
Jean-Claude Courvalin, Howard J. Worman, Richard W. Wozniak, Catherine Favreau, Thierry Frappier
Publikováno v:
Biochemistry. 35:8035-8044
During mitosis in higher eukaryotic cells, the nuclear envelope membranes break down into distinct populations of vesicles and the proteins of the nuclear lamina and the nuclear pore complexes disperse in the cytoplasm. Since phosphorylation can alte
Publikováno v:
European Journal of Biochemistry. 205:85-91
Tryptic digestion of brain spectrin generates a number of fragments from alpha and beta subunits; when these fragments are incubated with F-actin or neurofilament light subunit, four of them with molecular masses below 30 kDa sediment with the cytosk
Autor:
Wilma J. Friedman, Michael L. Shelanski, Thierry Frappier, Carol M. Troy, Sylvia A. Rabacchi, Kristy A. Brown
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 20(4)
β-amyloid (Aβ) has been proposed to play a role in the pathogenesis of Alzheimer's disease (AD). Deposits of insoluble Aβ are found in the brains of patients with AD and are one of the pathological hallmarks of the disease. It has been proposed th
Publikováno v:
Journal of the neurological sciences.
All eukaryotic cells have a cytoskeleton, consisting of microtubules, intermediate filaments and microfilaments. The cytoskeletal structure of cells and cell processes in the central nervous system is diverse. The generation of animal models in which
Autor:
Michael L. Shelanski, Timothy Lynch, Kristy A. Brown, Conrad L. Leung, Thierry Frappier, Nina S. Liang, Ronald K.H. Liem
Publikováno v:
FEBS Letters. (3):262-266
Mutations in the gene for the microtubule associated protein, tau have been identified for fronto-temporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17). In vitro data have shown that FTDP-17 mutant tau proteins have a reduced ability
Publikováno v:
European journal of biochemistry. 169(3)
Brain spectrin, or fodrin, a major protein of the subaxolemmal cytoskeleton, associates specifically in in vitro assays with the 70-kDa neurofilament subunit (NF-L) and with glial filaments from pig spinal cord. As an initial approach to the identifi