Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Thierry Forné"'
Autor:
Kim Philipp Jablonski, Leopold Carron, Julien Mozziconacci, Thierry Forné, Marc-Thorsten Hütt, Annick Lesne
Publikováno v:
Human Genomics, Vol 16, Iss 1, Pp 1-15 (2022)
Abstract Background Genome-wide association studies have identified statistical associations between various diseases, including cancers, and a large number of single-nucleotide polymorphisms (SNPs). However, they provide no direct explanation of the
Externí odkaz:
https://doaj.org/article/971c30040d5841b98ac163c4f768dd70
Autor:
Sébastien Calvet, Séphora Sallis, Nehmé Saksouk, Cosette Rebouissou, Catherine Teyssier, Annick Lesne, Florence Cammas, Thierry Forné
Publikováno v:
Cells, Vol 11, Iss 15, p 2392 (2022)
About half of the mammalian genome is constituted of repeated elements, among which endogenous retroviruses (ERVs) are known to influence gene expression and cancer development. The HP1 (Heterochromatin Protein 1) proteins are known to be essential f
Externí odkaz:
https://doaj.org/article/20bc96c941dd4f52aee07a8ac7ba44be
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2532
Recent works indicate that, at specific loci, interactions of chromatin with membrane-less organelles self-assembled through mechanisms of phase separation, like nuclear bodies, are crucial to regulate genome functions, and in particular transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ea5ec0527a01094d27e02c951226a37
https://pubmed.ncbi.nlm.nih.gov/35867250
https://pubmed.ncbi.nlm.nih.gov/35867250
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2532
Many population-based methods investigating chromatin dynamics and organization in eukaryotes are based on the chromosome conformation capture (3C) method. Here, we provide an updated version of the quantitative 3C (3C-qPCR) protocol for improved and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc6bcd55f111e6f998b584b33179aef6
https://pubmed.ncbi.nlm.nih.gov/35867242
https://pubmed.ncbi.nlm.nih.gov/35867242
Autor:
Mathias Boulanger, Chamseddine Kifagi, Marko Ristic, Ludovic Gabellier, Denis Tempé, Jon-Otti Sigurdsson, Tony Kaoma, Charlotte Andrieu-Soler, Thierry Forné, Eric Soler, Yosr Hicheri, Elise Gueret, Laurent Vallar, Jesper V Olsen, Guillaume Cartron, Marc Piechaczyk, Guillaume Bossis
Genotoxicants have been used for decades as front-line therapies against cancer on the basis of their DNA-damaging actions. However, some of their non-DNA-damaging effects are also instrumental for killing dividing cells. We report here that the anth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122e6cdfadecb7622d17dbc189910c18
https://doi.org/10.1101/2022.04.19.488613
https://doi.org/10.1101/2022.04.19.488613
Autor:
Jean-François Théroux, Jennie Yang, Kathryn Vaillancourt, Deborah C. Mash, Alberto J. López, Gustavo Turecki, Corina Nagy, Erin S. Calipari, Naguib Mechawar, Carl Ernst, Volodymyr Yerko, Benoit Labonté, Thierry Forné, Kimberly C. Thibeault, Gary G. Chen, Eric J. Nestler, Zahia Aouabed
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2021, 26, pp.3134-3151. ⟨10.1038/s41380-020-00909-x⟩
Molecular psychiatry
Molecular Psychiatry, Nature Publishing Group, 2021, 26, pp.3134-3151. ⟨10.1038/s41380-020-00909-x⟩
Molecular psychiatry
Epigenetic mechanisms, like those involving DNA methylation, are thought to mediate the relationship between chronic cocaine dependence and molecular changes in addiction-related neurocircuitry, but have been understudied in human brain. We initially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301da56c49f3dbafe88fcbb50acadd0c
https://doi.org/10.1038/s41380-020-00909-x
https://doi.org/10.1038/s41380-020-00909-x
Autor:
Alain R. Thierry, Jean-Daniel Abraham, David Gozal, Abdelnaby Khalyfa, Thierry Forné, Corinne Prévostel, Zahra Al Amir Dache, Amaelle Otandault, Salem Chouaib, Isabelle Jariel-Encontre
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2020, 122, pp.715-725. ⟨10.1038/s41416-019-0716-y⟩
British Journal of Cancer, Cancer Research UK, 2020, 122, pp.715-725. ⟨10.1038/s41416-019-0716-y⟩
Background We investigated the influence of hypoxia on the concentration of mitochondrial and nuclear cell-free DNA (McfDNA and NcfDNA, respectively). Method By an ultra-sensitive quantitative PCR-based assay, McfDNA and NcfDNA were measured in the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26860b91c0532c7b1b041c41d1484894
https://doi.org/10.1038/s41416-019-0716-y
https://doi.org/10.1038/s41416-019-0716-y
Publikováno v:
Spatial Genome Organization ISBN: 9781071624968
Spatial Genome Organization: Methods and Protocols
Spatial Genome Organization: Methods and Protocols, In press
Spatial Genome Organization: Methods and Protocols
Spatial Genome Organization: Methods and Protocols, In press
International audience; Many population-based methods investigating chromatin dynamics and organization in eukaryotes are based on the Chromosome Conformation Capture (3C) method. Here, we provide an updated version of the quantitative 3C (3C-qPCR) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27e53faf2a058207578aba28700b2b2
https://doi.org/10.1007/978-1-0716-2497-5_1
https://doi.org/10.1007/978-1-0716-2497-5_1
Publikováno v:
Spatial Genome Organization ISBN: 9781071624968
Spatial Genome Organization: Methods and Protocols
Spatial Genome Organization: Methods and Protocols, In press
Spatial Genome Organization: Methods and Protocols
Spatial Genome Organization: Methods and Protocols, In press
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a06baea8e0b23543abd18a88ef4bd9
https://doi.org/10.1007/978-1-0716-2497-5_9
https://doi.org/10.1007/978-1-0716-2497-5_9
Autor:
Annick Lesne, Kim Philipp Jablonski, Marc-Thorsten Hütt, Leopold Carron, Thierry Forné, Julien Mozziconacci
Publikováno v:
Human Genomics
Human Genomics, 2022, 16 (1), pp.2. ⟨10.1186/s40246-022-00375-2⟩
Human Genomics, Vol 16, Iss 1, Pp 1-15 (2022)
Human Genomics, 16 (1)
Human Genomics, 2022, 16 (1), pp.2. ⟨10.1186/s40246-022-00375-2⟩
Human Genomics, Vol 16, Iss 1, Pp 1-15 (2022)
Human Genomics, 16 (1)
Background Genome-wide association studies have identified statistical associations between various diseases, including cancers, and a large number of single-nucleotide polymorphisms (SNPs). However, they provide no direct explanation of the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3305500050c7821bee2d4b4418e0f22b
https://doi.org/10.21203/rs.3.rs-800781/v1
https://doi.org/10.21203/rs.3.rs-800781/v1