Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Thierry Durroux"'
Autor:
Paul Lambey, Omolade Otun, Xiaojing Cong, François Hoh, Luc Brunel, Pascal Verdié, Claire M Grison, Fanny Peysson, Sylvain Jeannot, Thierry Durroux, Cherine Bechara, Sébastien Granier, Cédric Leyrat
Publikováno v:
eLife, Vol 11 (2022)
Staphylococcus aureus (SA) leukocidin ED (LukED) belongs to a family of bicomponent pore forming toxins that play important roles in SA immune evasion and nutrient acquisition. LukED targets specific G protein-coupled chemokine receptors to lyse huma
Externí odkaz:
https://doaj.org/article/6a2d413ff8244168837148838406e319
Autor:
Amos Fumagalli, Joyce Heuninck, Anne Pizzoccaro, Enora Moutin, Joyce Koenen, Martial Séveno, Thierry Durroux, Marie-Pierre Junier, Géraldine Schlecht-Louf, Francoise Bachelerie, Dagmar Schütz, Ralf Stumm, Martine J. Smit, Nathalie C. Guérineau, Séverine Chaumont-Dubel, Philippe Marin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The atypical chemokine receptor 3 (ACKR3) is known to regulate cell migration, but the underlying mechanisms are unclear. Here, the authors show, from an interactome analysis, ACKR3 association with the gap junction protein Connexin 43 in vivo and AC
Externí odkaz:
https://doaj.org/article/15da11b062db485fa8b9ce8e0b203220
Autor:
Laura Lemel, Katarzyna Nieścierowicz, M. Dolores García-Fernández, Leonardo Darré, Thierry Durroux, Marta Busnelli, Mylène Pezet, Fabrice Rébeillé, Juliette Jouhet, Bernard Mouillac, Carmen Domene, Bice Chini, Vadim Cherezov, Christophe J. Moreau
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100059- (2021)
Abstract: Cholesterol is a major component of mammalian plasma membranes that not only affects the physical properties of the lipid bilayer but also is the function of many membrane proteins including G protein-coupled receptors. The oxytocin recepto
Externí odkaz:
https://doaj.org/article/5f3424606d3541d2a9d0b9ae1022eef1
Autor:
Nikaïa Smith, Nicolas Pietrancosta, Sophia Davidson, Jacques Dutrieux, Lise Chauveau, Pasquale Cutolo, Michel Dy, Daniel Scott-Algara, Bénédicte Manoury, Onofrio Zirafi, Isabelle McCort-Tranchepain, Thierry Durroux, Françoise Bachelerie, Olivier Schwartz, Jan Münch, Andreas Wack, Sébastien Nisole, Jean-Philippe Herbeuval
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Plasmacytoid dendritic cells produce type I interferons in response to viral sensing. Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement.
Externí odkaz:
https://doaj.org/article/4dcfeb35184e41db9075187f20ab2655
Autor:
Aurélien Zarca, Claudia Perez, Jelle van den Bor, Jan Paul Bebelman, Joyce Heuninck, Rianna J. F. de Jonker, Thierry Durroux, Henry F. Vischer, Marco Siderius, Martine J. Smit
Publikováno v:
Cells, Vol 10, Iss 3, p 618 (2021)
Background: The atypical chemokine receptor 3 (ACKR3) belongs to the superfamily of G protein-coupled receptors (GPCRs). Unlike classical GPCRs, this receptor does not activate G proteins in most cell types but recruits β-arrestins upon activation.
Externí odkaz:
https://doaj.org/article/a9f82835af6b4ec2a2d3395bee5a36f7
Autor:
Víctor Fernández-Dueñas, Jaume J. Taura, Martin Cottet, Maricel Gómez-Soler, Marc López-Cano, Catherine Ledent, Masahiko Watanabe, Eric Trinquet, Jean-Philippe Pin, Rafael Luján, Thierry Durroux, Francisco Ciruela
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 1, Pp 57-63 (2015)
Parkinson’s disease (PD) is a dopaminergic-related pathology in which functioning of the basal ganglia is altered. It has been postulated that a direct receptor-receptor interaction – i.e. of dopamine D2 receptor (D2R) with adenosine A2A receptor
Externí odkaz:
https://doaj.org/article/0b6a749120ef4f3698d09afc81337fd5
Autor:
David Moreno Delgado, Thor C Møller, Jeanne Ster, Jesús Giraldo, Damien Maurel, Xavier Rovira, Pauline Scholler, Jurriaan M Zwier, Julie Perroy, Thierry Durroux, Eric Trinquet, Laurent Prezeau, Philippe Rondard, Jean-Philippe Pin
Publikováno v:
eLife, Vol 6 (2017)
Metabotropic glutamate receptors (mGluRs) are mandatory dimers playing important roles in regulating CNS function. Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells
Externí odkaz:
https://doaj.org/article/45f8031aa1ce42f587b4ebe1846baae1
Autor:
Thierry Durroux, Jurriaan M. Zwier, Eric Trinquet, Orestis Faklaris, Martin Cottet, Jean-Philippe Pin
Publikováno v:
Pharmaceuticals, Vol 4, Iss 1, Pp 202-214 (2011)
The identification of new drugs exhibiting reduced adverse side-effects constitutes a great challenge for the next decade. Various steps are needed to screen for good ligand candidates and one of them is the evaluation of their binding properties. Ne
Externí odkaz:
https://doaj.org/article/ae64c31ca6164ee9b727fd83d074ad66
Autor:
Julie Tenenbaum, Mohammed A Ayoub, Sanja Perkovska, Anne-Laure Adra-Delenne, Christiane Mendre, Bruno Ranchin, Giamperro Bricca, Ghislaine Geelen, Bernard Mouillac, Thierry Durroux, Denis Morin
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8383 (2009)
Patients having the nephrogenic syndrome of inappropriate antidiuresis present either the R137C or R137L V2 mutated receptor. While the clinical features have been characterized, the molecular mechanisms of functioning of these two mutants remain elu
Externí odkaz:
https://doaj.org/article/aa40ae45383147fc8ef32249f3cb5e4e
Autor:
Omolade Otun, Paul Lambey, Xiaojing Cong, François Hoh, Luc Brunel, Pascal Verdié, Claire M Grison, Fanny Peysson, Sylvain Jeannot, Thierry Durroux, Cherine Bechara, Sébastien Granier, Cédric Leyrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02553b0b6388f49f39c0109219df91e6
https://doi.org/10.7554/elife.72555.sa2
https://doi.org/10.7554/elife.72555.sa2