Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Thierry D Flandre"'
Publikováno v:
Toxicologic pathology. 50(5)
CFZ533 (iscalimab) is a nondepleting anti-CD40 antibody intended for inhibition of transplant organ rejection and treatment of autoimmune diseases. In a safety assessment in rhesus monkeys, CFZ533 was administered for 13 weeks up to 150 mg/kg/week su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fceef472135a8d26a1c1fc3699ec02
https://pubmed.ncbi.nlm.nih.gov/35730205
https://pubmed.ncbi.nlm.nih.gov/35730205
Publikováno v:
Toxicologic Pathology. 49:286-295
Serelaxin is a recombinant human relaxin-2 intended for cardiovascular indications. Inhalation was chosen as alternative route to intravenous to allow daily administration for chronic applications and home treatment. A total of 4 short-term studies w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e077f52f16f4fc51764cf1ee3f02aa8
https://doi.org/10.1177/0192623320943129
https://doi.org/10.1177/0192623320943129
Publikováno v:
Toxicologic pathology. 49(2)
Though rare due to measures and practices to control the risk, infections can occur in research and toxicology studies, especially in nonhuman primates (NHPs) exposed to xenobiotics, particularly immunomodulatory drugs. With such xenobiotics, immunoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c8bf9a977558f6b9d3a89eccf4b151
https://pubmed.ncbi.nlm.nih.gov/32873219
https://pubmed.ncbi.nlm.nih.gov/32873219
Publikováno v:
Toxicologic pathology. 49(2)
Serelaxin is a recombinant human relaxin-2 intended for cardiovascular indications. Inhalation was chosen as alternative route to intravenous to allow daily administration for chronic applications and home treatment. A total of 4 short-term studies w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::674cc8e66e7a8131214877cada0c1278
https://pubmed.ncbi.nlm.nih.gov/32815455
https://pubmed.ncbi.nlm.nih.gov/32815455
Publikováno v:
Journal of Applied Physiology. 94:1129-1136
Double-chamber plethysmography has been recognized since 1979 as a reference technique to measure pulmonary function values in guinea pigs, but it has not gained attention for use in mice. Theoretically, however, this technique combines the advantage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddca3fcbbb6e94b5c16f80b70d26dd2
https://doi.org/10.1152/japplphysiol.00561.2002
https://doi.org/10.1152/japplphysiol.00561.2002