Zobrazeno 1 - 10
of 369
pro vyhledávání: '"Thierry Buclin"'
Autor:
Marie-Claude Addor, David Baud, Maya Berlin, Alice Panchaud, Thierry Buclin, François R Girardin, Ursula Winterfeld, Corinna Weber-Schoendorfer, Orna Diav-Citrin, Faiza Lamine, Kim Dao, Svetlana Shechtman, Reem Hegla Murad, Ariela Hazan, Jonathan L Richardson, Georgios Eleftheriou, Valentin Rousson, Leonore Diezi, David Haefliger, Ana Paula Simões-Wüst
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Objectives Glucagon-like peptide 1 receptor agonists (GLP1-RA) are indicated for the treatment of type 2 diabetes and more recently for weight loss. The aim of this study was to assess the risks associated with GLP1-RA exposure during early pregnancy
Externí odkaz:
https://doaj.org/article/0d9228cc67e8424b806167a253009ff7
Autor:
Paul Thoueille, Susana Alves Saldanha, Fabian Schaller, Eva Choong, Aline Munting, Matthias Cavassini, Dominique Braun, Huldrych F. Günthard, Katharina Kusejko, Bernard Surial, Hansjakob Furrer, Andri Rauch, Mathieu Rougemont, Pilar Ustero, Alexandra Calmy, Marcel Stöckle, Catia Marzolini, Caroline Di Benedetto, Enos Bernasconi, Patrick Schmid, Rein Jan Piso, Pascal Andre, François R. Girardin, Monia Guidi, Thierry Buclin, Laurent A. Decosterd
Publikováno v:
The Lancet Regional Health. Europe, Vol 36, Iss , Pp 100793- (2024)
Summary: Background: The efficacy and tolerability of long-acting cabotegravir and rilpivirine were demonstrated in Phase III trials. However, low concentrations combined with other risk factors have been associated with an increased risk of virologi
Externí odkaz:
https://doaj.org/article/6380ec40d9d94ba48ce0923cbe387561
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 711 (2024)
Most traditional cytotoxic drugs are characterized by steep dose–response relationships and narrow therapeutic windows [...]
Externí odkaz:
https://doaj.org/article/0d4a844d68e34f42a160e0cd2acbca0f
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 4, Pp 469-481 (2022)
Abstract Salbutamol was included in the prohibited list of the World Anti‐Doping Agency (WADA) in 2004. Although systemic intake is banned, inhalation for asthma is permitted but with dosage restrictions. The WADA established a urinary concentratio
Externí odkaz:
https://doaj.org/article/666df59a17874ee7afca9c848b19e77e
Autor:
Léonore Diezi, Kim Dao, Vincent Jullien, Caroline Roussel‐Maupetit, Ingrid Burton, Pascal André, Carine Bardinet, Laura E. Rothuizen, Haithem Chtioui, Maria A. Manso‐Silvan, Catherine Guittet, Françoise Brunner‐Ferber, Francois Vandenhende, Catherine Chiron, Luc‐André Granier, Thierry Buclin
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract Ethosuximide, the first‐line therapy for childhood absence epilepsy, is currently formulated as a syrup (Zarontin®, Pfizer) with a bitter taste and high sugar content, poorly adapted to children, and a ketogenic diet. The collaborative Eu
Externí odkaz:
https://doaj.org/article/1d34a011dc9f4059abd3c71a7c781907
Autor:
Antoine G. Schneider, Pascal André, Joerg Scheier, Monika Schmidt, Heiko Ziervogel, Thierry Buclin, Detlef Kindgen-Milles
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Cytokine hemoadsorption might be beneficial in patients with sepsis. However, its effect on anti-infective agents' disposition remains largely unknown. We sought to determine the influence of hemoadsorption on the pharmacokinetics of common
Externí odkaz:
https://doaj.org/article/baa4e73a6b9a4c3dad1d234ed5468cfc
Autor:
Myriam Briki, Pascal André, Yann Thoma, Nicolas Widmer, Anna D. Wagner, Laurent A. Decosterd, Thierry Buclin, Monia Guidi, Sandro Carrara
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1283 (2023)
Therapeutic drug monitoring (TDM) of conventional cytotoxic chemotherapies is strongly supported yet poorly implemented in daily practice in hospitals. Analytical methods for the quantification of cytotoxic drugs are instead widely presented in the s
Externí odkaz:
https://doaj.org/article/8ba180fcbde64a02942f560319a292a7
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1081 (2023)
Imatinib is a targeted cancer therapy that has significantly improved the care of patients with chronic myeloid leukemia (CML) and gastrointestinal stromal tumor (GIST). However, it has been shown that the recommended dosages of imatinib are associat
Externí odkaz:
https://doaj.org/article/c16005e152ce45049eef7c6700f01b38
Autor:
Pascal André, Léonore Diezi, Kim Dao, Pierre Alex Crisinel, Laura E. Rothuizen, Haithem Chtioui, Laurent Arthur Decosterd, Manuel Diezi, Sandra Asner, Thierry Buclin
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2022)
Introduction: Broad-spectrum beta-lactams are commonly prescribed for empirical or selective treatment of bacterial infections in children with malignancies. In the immunocompromised, appropriate concentration exposure is crucial to ensure antimicrob
Externí odkaz:
https://doaj.org/article/96c284a613334897b7fc1df0105c7eee
Autor:
Sylvain Goutelle, Yann Thoma, Roxane Buffet, Michael Philippe, Thierry Buclin, Monia Guidi, Chantal Csajka
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2107 (2022)
Busulfan, a drug used in conditioning prior to hematopoietic stem cell transplantation (HSCT) in children, has a narrow therapeutic margin. The model-informed precision dosing (MIPD) of busulfan is desirable, but there is a lack of validated tools. T
Externí odkaz:
https://doaj.org/article/0a811a747d7a44b69b3791c248263d27