Comorbidity between lung cancer and COVID-19 pneumonia: role of immunoregulatory gene transcripts in high -expressing normal lung

Autor: Vladimir Lazar, Jacques Raynaud, Shai Magidi, Catherine Bresson, Jean-François Martini, Susan Galbraith, Fanny Wunder, Amir Onn, Gerald Batist, Nicolas Girard, Ulrik Lassen, C. S. Pramesh, Amal Al-Omari, Sadakatsu Ikeda, Guy Berchem, Jean-Yves Blay, Benjamin Solomon, Enriqueta Felip, Josep Tabernero, Eitan Rubin, Thierry Philip, Angel Porgador, Ioana Berindan-Neagoe, Richard L. Schilsky, Razelle Kurzrock

Publikováno v: Therapeutic Advances in Medical Oncology, Vol 14 (2022)

Background: SARS-CoV-2 (COVID-19) elicits a T-cell antigen-mediated immune response of variable efficacy. To understand this variability, we explored transcriptomic expression of angiotensin-converting enzyme 2 ( ACE2 , the SARS-CoV-2 receptor) and o

Externí odkaz: https://doaj.org/article/cacbf20affbf406896e87fc22d539ae7

Towards a cancer mission in Horizon Europe: recommendations

Autor: Anton Berns, Ulrik Ringborg, Julio E. Celis, Manuel Heitor, Neil K. Aaronson, Nancy Abou‐Zeid, Hans‐Olov Adami, Kathi Apostolidis, Michael Baumann, Alberto Bardelli, René Bernards, Yvonne Brandberg, Carlos Caldas, Fabien Calvo, Caroline Dive, Angelika Eggert, Alexander Eggermont, Carolina Espina, Frederik Falkenburg, Jérôme Foucaud, Douglas Hanahan, Ulrike Helbig, Bengt Jönsson, Mette Kalager, Sakari Karjalainen, Miklós Kásler, Pamela Kearns, Klas Kärre, Denis Lacombe, Francesco deLorenzo, Françoise Meunier, Gerd Nettekoven, Simon Oberst, Péter Nagy, Thierry Philip, Richard Price, Joachim Schüz, Eric Solary, Peter Strang, Josep Tabernero, Emile Voest

Publikováno v: Molecular Oncology, Vol 14, Iss 8, Pp 1589-1615 (2020)

A comprehensive translational cancer research approach focused on personalized and precision medicine, and covering the entire cancer research–care–prevention continuum has the potential to achieve in 2030 a 10‐year cancer‐specific survival f

Externí odkaz: https://doaj.org/article/938c652480cf4543b4c52b6778cd7da0

European Groundshot—addressing Europe's cancer research challenges: a Lancet Oncology Commission

Autor: Mark Lawler, Lynne Davies, Simon Oberst, Kathy Oliver, Alexander Eggermont, Anna Schmutz, Carlo La Vecchia, Claudia Allemani, Yolande Lievens, Peter Naredi, Tanja Cufer, Ajay Aggarwal, Matti Aapro, Kathi Apostolidis, Anne-Marie Baird, Fatima Cardoso, Andreas Charalambous, Michel P Coleman, Alberto Costa, Mirjam Crul, Csaba L Dégi, Federica Di Nicolantonio, Sema Erdem, Marius Geanta, Jan Geissler, Jacek Jassem, Beata Jagielska, Bengt Jonsson, Daniel Kelly, Olaf Kelm, Teodora Kolarova, Tezer Kutluk, Grant Lewison, Françoise Meunier, Jana Pelouchova, Thierry Philip, Richard Price, Beate Rau, Isabel T Rubio, Peter Selby, Maja Južnič Sotlar, Gilliosa Spurrier-Bernard, Jolanda C van Hoeve, Eduard Vrdoljak, Willien Westerhuis, Urszula Wojciechowska, Richard Sullivan

Publikováno v: Lawler, M, Davies, L, Oberst, S, Oliver, K, Eggermont, A, Schmutz, A, La Vecchia, C, Allemani, C, Lievens, Y, Naredi, P, Cufer, T, Aggarwal, A, Aapro, M, Apostolidis, K, Baird, A-M, Cardoso, F, Charalambous, A, Coleman, M P, Costa, A, Crul, M, Dégi, C L, Di Nicolantonio, F, Erdem, S, Geanta, M, Geissler, J, Jassem, J, Jagielska, B, Jonsson, B, Kelly, D, Kelm, O, Kolarova, T, Kutluk, T, Lewison, G, Meunier, F, Pelouchova, J, Philip, T, Price, R, Rau, B, Rubio, I T, Selby, P, Južnič Sotlar, M, Spurrier-Bernard, G, van Hoeve, J C, Vrdoljak, E, Westerhuis, W, Wojciechowska, U & Sullivan, R 2023, ' European Groundshot-addressing Europe's cancer research challenges : a Lancet Oncology Commission ', Lancet Oncology, vol. 24, no. 1, pp. e11-e56 . https://doi.org/10.1016/S1470-2045(22)00540-X

Cancer research is a crucial pillar for countries to deliver more affordable, higher quality, and more equitable cancer care. Patients treated in research-active hospitals have better outcomes than patients who are not treated in these settings. Howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e07d8fcab1f498ebdd71513b8c10c4d
https://doi.org/10.1016/s1470-2045(22)00540-x

Moonshot or groundshot: addressing Europe's cancer challenge through a patient-focused, data-enabled lens

Autor: Yolande Lievens, Peter Naredi, Mark Lawler, Matti Aapro, Ian Banks, Thierry Philip, Françoise Meunier, Jacek Jassem, Maja Južnič Sotlar, Richard Sullivan, Jana Pelouchova, Giles Vassal, Tanja Cufer

Publikováno v: The Lancet Oncology. 20:1482-1485

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81f055baeb040b03bea2b8419e157e0
https://doi.org/10.1016/s1470-2045(19)30648-5

Transcriptomics in Tumor and Normal Tissues and Precision Oncology Algorithms Identify Early-Stage NSCLC Patients with High Risk of Post-Surgery Recurrence Who May Benefit from Adjuvant Therapies

Autor: Vladimir Lazar, Haiquan Chen, Jacques Raynaud, Raanan Berger, Jean-Yves Blay, Ulrik Lassen, Benjamin Solomon, Enriqueta Felip, Alan Spatz, Eric Raymond, Richard L., Ioana Berindan-Neagoe, C. S. Pramesh, Amir Onn, Angel Porgador, Susan Galbraith, Gerald Batist, Philipppe Girard, Shai Magidi, Marina Sekacheva, Hovav Nechushtan, Nicolas Girard, Razelle Kurkrock, Eitan Rubin, Josep Tabernero, Amal Al-Omari, Jean-Francois Martini, Catherine Bresson, Thierry Philip, Sadakatsu Ikeda

Publikováno v: SSRN Electronic Journal.

Background: The prognosis of patients with non-small cell lung cancer (NSCLC) is traditionally determined by anatomic staging using the Tumor, Node, Metastasis (TNM) staging system. TNM staging neglects the biological features of the tumor that may b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab959256f20381b217c708f18d595784
https://doi.org/10.2139/ssrn.3910351