Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Thierry, Le Chevalier"'
Autor:
Andrea S, Fung, Maryam, Karimi, Stefan, Michiels, Lesley, Seymour, Elisabeth, Brambilla, Thierry, Le-Chevalier, Jean-Charles, Soria, Robert, Kratzke, Stephen L, Graziano, Siddhartha, Devarakonda, Ramaswamy, Govindan, Ming-Sound, Tsao, Frances A, Shepherd
Publikováno v:
Transl Lung Cancer Res
BACKGROUND: In the current analysis, we characterize the prognostic significance of KRAS mutations with concomitant copy number aberrations (CNA) in early stage non-small cell lung cancer (NSCLC), and evaluate the ability to predict survival benefit
Autor:
Benjamin Besse, Dominique Fabre, Sacha Mussot, Stéphane Collaud, Olaf Mercier, Bastien Provost, Elie Fadel, Thierry Le Chevalier
Publikováno v:
Journal of Surgical Oncology. 117:1570-1574
Background Traditionally, treatment for stage IIIB (T4N2M0 and T1-4N3M0) NSCLC consists in definitive chemoradiation. Surgery is used only anecdotally. Here, we studied outcome for patients treated with multimodality including surgery. Methods Patien
Autor:
Elizabeth Brambilla, Thierry Le Chevalier, Gwénaël Le Teuff, Benjamin Lacas, Pierre Hainaut, Robert A. Kratzke, Stephen L. Graziano, Martin Filipits, Ming-Sound Tsao, R. Pirker, Jean-Charles Soria, Jean-Yves Douillard, Frances A. Shepherd, Pasi A. Jänne, L. Seymour, Jean-Pierre Pignon
Publikováno v:
Journal of Clinical Oncology. 35:2018-2027
Purpose Our previous work evaluated individual prognostic and predictive roles of TP53, KRAS, and EGFR in non–small-cell lung cancer (NSCLC). In this analysis, we explore the prognostic and predictive roles of TP53/KRAS and TP53/EGFR comutations in
Autor:
Elisabeth Brambilla, Stephen L. Graziano, Frances A. Shepherd, Maryam Karimi, Jean-Charles Soria, Siddhartha Devarakonda, Ramaswamy Govindan, Lesley Seymour, Robert A. Kratzke, Stefan Michiels, Ming-Sound Tsao, Thierry Le Chevalier, Andrea S. Fung
Publikováno v:
Journal of Clinical Oncology. 38:e21080-e21080
e21080 Background: The prognostic and predictive role of KRAS mutations and gene copy number aberrations (CNA) in early stage NSCLC is unclear. In this study, we characterize the prognostic effect of KRAS mutation status and concomitant CN gain in ea
Autor:
Olaf Mercier, Vincent Thomas de Montpréville, Ludovic Lacroix, Thierry Le Chevalier, Antoinette Lemoine, Benjamin Besse, Peter Dorfmüller, Elie Fadel, Maria-Rosa Ghigna
Publikováno v:
Pathology, research and practice. 213(7)
Objectives EGFR and KRAS genes are routinely tested in lung carcinomas with therapeutic implications. However the current testing methods require complex infrastructures and the delay for diagnosis remains often rather long, especially for initiating
Autor:
Thierry Le Chevalier, Helmut Popper, Martin Filipits, Anne-Lise Vataire, Jean Mendiboure, Ariane Dunant, Elisabeth Brambilla, Robert Pirker, Pierre Hainaut, Haiji Sun, Jean-Charles Soria, Vanessa Rousseau, Xiaoli Ma, Sylvie Lantuejoul
Publikováno v:
Molecular Oncology; Vol 8
Molecular Oncology
Molecular Oncology
Adjuvant cisplatin-based chemotherapy only marginally improves survival in patients with completely resected non-small-cell lung cancer (NSCLC). We have evaluated the predictive value of mutations in TP53, encoding the tumour suppressor p53, in the I
Autor:
Tit Albreht, Anita Kienesberger, Anita Waldmann, Geoffrey Henning, Françoise Meunier, Gilly Spurrier-Bernard, David Weller, Peter Selby, Tomas Lindahl, Thierry Le Chevalier, Mariano Barbacid, Wendy Yared, Kate Law, Peter Naredi, Jola Gore-Booth, Aimery de Gramont, Roger Wilson, Joan Kelly, Carlo La Vecchia, Jan Geissler, Harald Zur Hausen, Pierfranco Conte, Bob Pinedo, Rebecca Malby, Peter Kapitein, Richard Sullivan, Sarper Diler, Stein Kaasa, Patrick G. Johnston, Sakari Karjalainen, Jean Pierre Armand, Denis Lacombe, Christoph C. Zielinski, Volker Diehl, Francesco De Lorenzo, Sema Erdem, Denis Horgan, Ian Banks, Bert Van Herk, Jacek Jassem, Cornelis J.H. van de Velde, David Cameron, Lucio Luzzatto, Jonas Bergh, Martin J. Murphy, Nils Wilking, Josep Tabernero, Jonathan Pearce, Peter Johnson, Mark Lawler, Kathy Oliver, Liselotte Højgaard, Filippo de Braud, Jana Pelouchov, Ken Mastris, Michèle Barzach, Paul Nurse, Bob Löwenberg, Martine Piccart, Peter Vedsted
Publikováno v:
European Cancer Concord (ECC) 2016, ' The European Cancer Patient's Bill of Rights, update and implementation 2016 ', ESMO Open, vol. 1, no. 6, e000127 . https://doi.org/10.1136/esmoopen-2016-000127
ESMO Open
ESMO Open, 1 (6
Lawler, M, Banks, I, Law, K, Albreht, T, Armand, J-P, Barbacid, M, Barzach, M, Bergh, J, Cameron, D, Conte, P, de Braud, F, de Gramont, A, de Lorenzo, F, Diehl, V, Diler, S, Erdem, S, Geissler, J, Gore-Booth, J, Henning, G, Højgaard, L, Horgan, D, Jassem, J, Johnson, P, Kaasa, S, Kapitein, P, Karjalainen, S, Kelly, J, Kienesberger, A, la Vecchia, C, Lacombe, D, Lindahl, T, Löwenberg, B, Luzzatto, L, Malby, R, Mastris, K, Meunier, F, Murphy, M, Naredi, P, Nurse, P, Oliver, K, Pearce, J, Pelouchov, J, Piccart, M, Pinedo, B, Spurrier-Bernard, G, Sullivan, R, Tabernero, J, van de Velde, C, van Herk, B, Vedsted, P, Waldmann, A, Weller, D, Wilking, N, Wilson, R, Yared, W, Zielinski, C, Zur Hausen, H, le Chevalier, T, Johnston, P & Selby, P 2016, ' The European Cancer Patient's Bill of Rights, update and implementation 2016 ', ESMO OPEN, vol. 1, no. 6, e000127 . https://doi.org/10.1136/esmoopen-2016-000127
Højgaard, L, Löwenberg, B, Selby, P, Lawler, M, Banks, I, Law, K, Albreht, T, Armand, J-P, Barbacid, M, Barzach, M, Bergh, J, Cameron, D, Conte, P, de Braud, F, de Gramont, A, De Lorenzo, F, Diehl, V, Diler, S, Erdem, S, Geissler, J, Gore-Booth, J, Henning, G, Horgan, D, Jassem, J, Johnson, P, Kaasa, S, Kapitein, P, Karjalainen, S, Kelly, J, Kienesberger, A, La Vecchia, C, Lacombe, D, Lindahl, T, Luzzatto, L, Malby, R, Mastris, K, Meunier, F, Murphy, M, Naredi, P, Nurse, P, Oliver, K, Pearce, J, Pelouchov, J, Piccart, M, Pinedo, B, Spurrier-Bernard, G, Sullivan, R, Tabernero, J, Van de Velde, C, van Herk, B, Vedsted, P, Waldmann, A, Weller, D, Wilking, N, Wilson, R, Yared, W, Zielinski, C, Zur Hausen, H, Le Chevalier, T & Johnston, P 2016, ' The European Cancer Patient's Bill of Rights, update and implementation 2016 ', ESMO Open, vol. 1, no. 6, e000127 . https://doi.org/10.1136/esmoopen-2016-000127
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Lawler, M, Banks, I, Law, K, Albreht, T, Armand, J, Barbacid, M, Barzach, M, Bergh, J, Cameron, D, Conte, P, De Braud, F, De Gramont, A, De Lorenzo, F, Diehl, V, Diler, S, Erdem, S, Geissler, J, Gore-booth, J, Henning, G, Højgaard, L, Horgan, D, Jassem, J, Johnson, P, Kaasa, S, Kapitein, P, Karjalainen, S, Kelly, J, Kienesberger, A, La Vecchia, C, Lacombe, D, Lindahl, T, Löwenberg, B, Luzzatto, L, Malby, R, Mastris, K, Meunier, F, Murphy, M, Naredi, P, Nurse, P, Oliver, K, Pearce, J, Pelouchov, J, Piccart, M, Pinedo, B, Spurrier-bernard, G, Sullivan, R, Tabernero, J, Van De Velde, C, Van Herk, B, Vedsted, P, Waldmann, A, Weller, D, Wilking, N, Wilson, R, Yared, W, Zielinski, C, Zur Hausen, H, Le Chevalier, T, Johnston, P & Selby, P 2017, ' The European Cancer Patient’s Bill of Rights, update and implementation 2016 ', ESMO Open, vol. 1, no. 6, pp. e000127 . https://doi.org/10.1136/esmoopen-2016-000127
ESMO Open
ESMO Open, 1 (6
Lawler, M, Banks, I, Law, K, Albreht, T, Armand, J-P, Barbacid, M, Barzach, M, Bergh, J, Cameron, D, Conte, P, de Braud, F, de Gramont, A, de Lorenzo, F, Diehl, V, Diler, S, Erdem, S, Geissler, J, Gore-Booth, J, Henning, G, Højgaard, L, Horgan, D, Jassem, J, Johnson, P, Kaasa, S, Kapitein, P, Karjalainen, S, Kelly, J, Kienesberger, A, la Vecchia, C, Lacombe, D, Lindahl, T, Löwenberg, B, Luzzatto, L, Malby, R, Mastris, K, Meunier, F, Murphy, M, Naredi, P, Nurse, P, Oliver, K, Pearce, J, Pelouchov, J, Piccart, M, Pinedo, B, Spurrier-Bernard, G, Sullivan, R, Tabernero, J, van de Velde, C, van Herk, B, Vedsted, P, Waldmann, A, Weller, D, Wilking, N, Wilson, R, Yared, W, Zielinski, C, Zur Hausen, H, le Chevalier, T, Johnston, P & Selby, P 2016, ' The European Cancer Patient's Bill of Rights, update and implementation 2016 ', ESMO OPEN, vol. 1, no. 6, e000127 . https://doi.org/10.1136/esmoopen-2016-000127
Højgaard, L, Löwenberg, B, Selby, P, Lawler, M, Banks, I, Law, K, Albreht, T, Armand, J-P, Barbacid, M, Barzach, M, Bergh, J, Cameron, D, Conte, P, de Braud, F, de Gramont, A, De Lorenzo, F, Diehl, V, Diler, S, Erdem, S, Geissler, J, Gore-Booth, J, Henning, G, Horgan, D, Jassem, J, Johnson, P, Kaasa, S, Kapitein, P, Karjalainen, S, Kelly, J, Kienesberger, A, La Vecchia, C, Lacombe, D, Lindahl, T, Luzzatto, L, Malby, R, Mastris, K, Meunier, F, Murphy, M, Naredi, P, Nurse, P, Oliver, K, Pearce, J, Pelouchov, J, Piccart, M, Pinedo, B, Spurrier-Bernard, G, Sullivan, R, Tabernero, J, Van de Velde, C, van Herk, B, Vedsted, P, Waldmann, A, Weller, D, Wilking, N, Wilson, R, Yared, W, Zielinski, C, Zur Hausen, H, Le Chevalier, T & Johnston, P 2016, ' The European Cancer Patient's Bill of Rights, update and implementation 2016 ', ESMO Open, vol. 1, no. 6, e000127 . https://doi.org/10.1136/esmoopen-2016-000127
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Lawler, M, Banks, I, Law, K, Albreht, T, Armand, J, Barbacid, M, Barzach, M, Bergh, J, Cameron, D, Conte, P, De Braud, F, De Gramont, A, De Lorenzo, F, Diehl, V, Diler, S, Erdem, S, Geissler, J, Gore-booth, J, Henning, G, Højgaard, L, Horgan, D, Jassem, J, Johnson, P, Kaasa, S, Kapitein, P, Karjalainen, S, Kelly, J, Kienesberger, A, La Vecchia, C, Lacombe, D, Lindahl, T, Löwenberg, B, Luzzatto, L, Malby, R, Mastris, K, Meunier, F, Murphy, M, Naredi, P, Nurse, P, Oliver, K, Pearce, J, Pelouchov, J, Piccart, M, Pinedo, B, Spurrier-bernard, G, Sullivan, R, Tabernero, J, Van De Velde, C, Van Herk, B, Vedsted, P, Waldmann, A, Weller, D, Wilking, N, Wilson, R, Yared, W, Zielinski, C, Zur Hausen, H, Le Chevalier, T, Johnston, P & Selby, P 2017, ' The European Cancer Patient’s Bill of Rights, update and implementation 2016 ', ESMO Open, vol. 1, no. 6, pp. e000127 . https://doi.org/10.1136/esmoopen-2016-000127
In this implementation phase of the European Cancer Patient's Bill of Rights (BoR), we confirm the following three patient-centred principles that underpin this initiative: The right of every European citizen to receive the most accurate information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9966a34bb99b5c6c6007869bd53fa136
https://pure.qub.ac.uk/en/publications/f86fd90a-d404-4605-98ca-f974ee3999c4
https://pure.qub.ac.uk/en/publications/f86fd90a-d404-4605-98ca-f974ee3999c4
Autor:
Stephen L. Graziano, Ming-Sound Tsao, Jean-Charles Soria, Benjamin Lacas, Lesley Seymour, Anthony Reiman, Gwénaël Le Teuff, Frances A. Shepherd, Thierry Le Chevalier, Robert Pirker, Elisabeth Brambilla, Jean-Yves Douillard, Anne McLeer, Sarit Aviel-Ronen, Ariane Dunant, Béranger Lueza, Martin Filipits, Jean-Pierre Pignon, Rafael Rosell, Robert A. Kratzke
Publikováno v:
Clinical Lung Cancer. 20:66-73.e6
Background Complete resection of non–small-cell lung cancer (NSCLC) offers the potential for cure after surgery and adjuvant chemotherapy. Patients may not benefit and may experience severe toxicity. There are no validated molecular tools to allow
Publikováno v:
European Respiratory Journal. 46:280-282
TKI should be used sequentially with chemotherapy and local procedures to prolong life in EGFR -mutated lung cancer http://ow.ly/KRWP4
Autor:
Hepp de los Rios Rodrigo, Thomas Gauler, Stephan Bildat, Siegfried Seeber, B. Fischer, Georgios Stamatis, Thomas Krbek, Dirk Theegarten, C. Lepechoux, C. Poettgen, Martin Stuschke, Dominique Grunenwald, Thierry Le Chevalier, Wilfried Eberhardt, Stefan Welter
Publikováno v:
Lung Cancer. 82:83-89
Induction chemoradiotherapy plus surgery remains an option to study in IIIA(N2) and selected IIIB NSCLC. Here we report ten-year long-term survival of a prospective multicenter German-French phase-II trial with trimodality.Mediastinoscopically proven