Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Thierry, Le Chevalier"'
Autor:
Benjamin Besse, Mélinda Charrier, Valérie Lapierre, Eric Dansin, Olivier Lantz, David Planchard, Thierry Le Chevalier, Alain Livartoski, Fabrice Barlesi, Agnès Laplanche, Stéphanie Ploix, Nadège Vimond, Isabelle Peguillet, Clotilde Théry, Ludovic Lacroix, Inka Zoernig, Kavita Dhodapkar, Madhav Dhodapkar, Sophie Viaud, Jean-Charles Soria, Katrin S. Reiners, Elke Pogge von Strandmann, Frédéric Vély, Sylvie Rusakiewicz, Alexander Eggermont, Jonathan M. Pitt, Laurence Zitvogel, Nathalie Chaput
Publikováno v:
OncoImmunology, Vol 5, Iss 4 (2016)
Dendritic cell-derived exosomes (Dex) are small extracellular vesicles secreted by viable dendritic cells. In the two phase-I trials that we conducted using the first generation of Dex (IFN-γ-free) in end-stage cancer, we reported that Dex exerted n
Externí odkaz:
https://doaj.org/article/c7a0a68f62ab4eb68ba7db4a61d68e2f
Autor:
Andrea S, Fung, Maryam, Karimi, Stefan, Michiels, Lesley, Seymour, Elisabeth, Brambilla, Thierry, Le-Chevalier, Jean-Charles, Soria, Robert, Kratzke, Stephen L, Graziano, Siddhartha, Devarakonda, Ramaswamy, Govindan, Ming-Sound, Tsao, Frances A, Shepherd
Publikováno v:
Transl Lung Cancer Res
BACKGROUND: In the current analysis, we characterize the prognostic significance of KRAS mutations with concomitant copy number aberrations (CNA) in early stage non-small cell lung cancer (NSCLC), and evaluate the ability to predict survival benefit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::775965608532ca7f050cd094f82f9172
https://pubmed.ncbi.nlm.nih.gov/33718025
https://pubmed.ncbi.nlm.nih.gov/33718025
Autor:
Benjamin Besse, Dominique Fabre, Sacha Mussot, Stéphane Collaud, Olaf Mercier, Bastien Provost, Elie Fadel, Thierry Le Chevalier
Publikováno v:
Journal of Surgical Oncology. 117:1570-1574
Background Traditionally, treatment for stage IIIB (T4N2M0 and T1-4N3M0) NSCLC consists in definitive chemoradiation. Surgery is used only anecdotally. Here, we studied outcome for patients treated with multimodality including surgery. Methods Patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b44dda487a1830c37593bb45ccd221e
https://doi.org/10.1002/jso.25042
https://doi.org/10.1002/jso.25042
Autor:
Elizabeth Brambilla, Thierry Le Chevalier, Gwénaël Le Teuff, Benjamin Lacas, Pierre Hainaut, Robert A. Kratzke, Stephen L. Graziano, Martin Filipits, Ming-Sound Tsao, R. Pirker, Jean-Charles Soria, Jean-Yves Douillard, Frances A. Shepherd, Pasi A. Jänne, L. Seymour, Jean-Pierre Pignon
Publikováno v:
Journal of Clinical Oncology. 35:2018-2027
Purpose Our previous work evaluated individual prognostic and predictive roles of TP53, KRAS, and EGFR in non–small-cell lung cancer (NSCLC). In this analysis, we explore the prognostic and predictive roles of TP53/KRAS and TP53/EGFR comutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f8c41604c006cf916e610c87e3417d
https://doi.org/10.1200/jco.2016.71.2893
https://doi.org/10.1200/jco.2016.71.2893
Autor:
Elisabeth Brambilla, Stephen L. Graziano, Frances A. Shepherd, Maryam Karimi, Jean-Charles Soria, Siddhartha Devarakonda, Ramaswamy Govindan, Lesley Seymour, Robert A. Kratzke, Stefan Michiels, Ming-Sound Tsao, Thierry Le Chevalier, Andrea S. Fung
Publikováno v:
Journal of Clinical Oncology. 38:e21080-e21080
e21080 Background: The prognostic and predictive role of KRAS mutations and gene copy number aberrations (CNA) in early stage NSCLC is unclear. In this study, we characterize the prognostic effect of KRAS mutation status and concomitant CN gain in ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbfd8c9ddffcf8a8105a47db76b1e6e4
https://doi.org/10.1200/jco.2020.38.15_suppl.e21080
https://doi.org/10.1200/jco.2020.38.15_suppl.e21080
Autor:
Olaf Mercier, Vincent Thomas de Montpréville, Ludovic Lacroix, Thierry Le Chevalier, Antoinette Lemoine, Benjamin Besse, Peter Dorfmüller, Elie Fadel, Maria-Rosa Ghigna
Publikováno v:
Pathology, research and practice. 213(7)
Objectives EGFR and KRAS genes are routinely tested in lung carcinomas with therapeutic implications. However the current testing methods require complex infrastructures and the delay for diagnosis remains often rather long, especially for initiating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3301e33b02e5b6ad592c4a3b175a035b
https://pubmed.ncbi.nlm.nih.gov/28554746
https://pubmed.ncbi.nlm.nih.gov/28554746
Autor:
Thierry Le Chevalier, Helmut Popper, Martin Filipits, Anne-Lise Vataire, Jean Mendiboure, Ariane Dunant, Elisabeth Brambilla, Robert Pirker, Pierre Hainaut, Haiji Sun, Jean-Charles Soria, Vanessa Rousseau, Xiaoli Ma, Sylvie Lantuejoul
Publikováno v:
Molecular Oncology; Vol 8
Molecular Oncology
Molecular Oncology
Adjuvant cisplatin-based chemotherapy only marginally improves survival in patients with completely resected non-small-cell lung cancer (NSCLC). We have evaluated the predictive value of mutations in TP53, encoding the tumour suppressor p53, in the I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26eea87ed775ab9a426b054c3e558ba4
Autor:
Stephen L. Graziano, Ming-Sound Tsao, Jean-Charles Soria, Benjamin Lacas, Lesley Seymour, Anthony Reiman, Gwénaël Le Teuff, Frances A. Shepherd, Thierry Le Chevalier, Robert Pirker, Elisabeth Brambilla, Jean-Yves Douillard, Anne McLeer, Sarit Aviel-Ronen, Ariane Dunant, Béranger Lueza, Martin Filipits, Jean-Pierre Pignon, Rafael Rosell, Robert A. Kratzke
Publikováno v:
Clinical Lung Cancer. 20:66-73.e6
Background Complete resection of non–small-cell lung cancer (NSCLC) offers the potential for cure after surgery and adjuvant chemotherapy. Patients may not benefit and may experience severe toxicity. There are no validated molecular tools to allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c150877d6193b69dbb3c3939604601b
https://doi.org/10.1016/j.cllc.2018.10.001
https://doi.org/10.1016/j.cllc.2018.10.001
Publikováno v:
European Respiratory Journal. 46:280-282
TKI should be used sequentially with chemotherapy and local procedures to prolong life in EGFR -mutated lung cancer http://ow.ly/KRWP4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0e5d5c37f364768f5e914a8c3f9d807
https://doi.org/10.1183/09031936.00017315
https://doi.org/10.1183/09031936.00017315
Autor:
Elie Fadel, Frédéric Kolb, Olaf Mercier, Thierry Le Chevalier, Philippe Dartevelle, Dominique Fabre, Sacha Mussot
Publikováno v:
The Annals of Thoracic Surgery. 96:1146-1155
Background Fifty years of surgical research using synthetic materials and heterologous tissues failed to find a good, durable replacement for the trachea. We investigated autologous tracheal substitution (ATS) without synthetic material or immunosupp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7fc20570db655c7ee375fc361eec69
https://doi.org/10.1016/j.athoracsur.2013.05.073
https://doi.org/10.1016/j.athoracsur.2013.05.073