Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Thienne Rocha Pires"'
Autor:
Andrea Janz Moreira, Thienne Rocha Pires, Jaqueline Nascimento Picada, Alexandre Simões Dias, Cláudio Augusto Marroni, Norma Possa Marroni, Fábio Cangeri Di Naso, Elizângela Gonçalves Schemitt, Graziella Rodrigues, Silvia Bona
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Objective. In this study, we evaluated the efficacy of simvastatin in the treatment of nonalcoholic steatohepatitis induced by methionine and choline-deficient diet in mice and its possible effect on factors involved in the pathogenesis of the diseas
Autor:
Débora Kuck Mausolff Papke, Vanessa Rodrigues Coelho, Patrícia Pereira, Natália Decker, Thienne Rocha Pires, Pricila Pflüger, Jaqueline Nascimento Picada, Karen Sousa
Publikováno v:
Psychopharmacology. 234:129-136
Vigabatrin (VGB) is a drug indicated mostly for the treatment of spasms in childhood and West’s syndrome patients. This drug inhibits irreversibly the enzyme GABA-transaminase (GABA-T), increasing GABA concentrations and enhancing GABAergic neurotr
Autor:
Débora Kuck Mausolff Papke, Caroline Gonçalves Vieira, Jaqueline Nascimento Picada, Ionara Rodrigues Siqueira, Thienne Rocha Pires, Felipe dos Santos Moysés, Patrícia Pereira, Luana Pereira de Souza, Carla Basso, Vanessa Rodrigues Coelho
Publikováno v:
Life Sciences. 122:65-71
Aims Antioxidant compounds have been extensively investigated as a pharmacological alternatives to prevent epileptogenesis. Rosmarinic acid (RA) and caffeic acid (CA) are compounds with antioxidant properties, and RA has been shown to inhibit GABA tr
Autor:
VR Coelho, Priscila Guedes Pereira, LP de Souza, Jaqueline Nascimento Picada, Rva Schunck, Dkm Papke, Karen Sousa, Mirna Bainy Leal, Thienne Rocha Pires, CG Vieira
Publikováno v:
Humanexperimental toxicology. 35(9)
Vigabatrin (VGB) is an antiepileptic drug thatincreases brain γ-aminobutyric acid (GABA) levels through irreversible inhibition of GABA transaminase. The aim of this study was to evaluate neurotoxicological effects of VGB measuring motor activity an