Tentonin 3 is a pore-forming subunit of a slow inactivation mechanosensitive channel

Autor: Sungmin Pak, Hyunil Ryu, Sujin Lim, Thien-Luan Nguyen, Sungwook Yang, Sumin Kang, Yeon Gyu Yu, Junhyuk Woo, Chanjin Kim, Cristina Fenollar-Ferrer, John N. Wood, Mi-Ock Lee, Gyu-Sang Hong, Kyungreem Han, Tae Song Kim, Uhtaek Oh

Publikováno v: Cell Reports, Vol 43, Iss 6, Pp 114334- (2024)

Summary: Mechanically activating (MA) channels transduce numerous physiological functions. Tentonin 3/TMEM150C (TTN3) confers MA currents with slow inactivation kinetics in somato- and barosensory neurons. However, questions were raised about its rol

Externí odkaz: https://doaj.org/article/24c1e3aeacd941c0a941fb4c98cf0b97

Tentonin 3/TMEM150C senses blood pressure changes in the aortic arch

Autor: Pan Dong Ryu, Gyu-Sang Hong, Mi-Ock Lee, Uhtaek Oh, Sungmin Pak, H. J. Kim, Sung-Yon Kim, Yiming Shen, Dongyoon Kim, Thien-Luan Nguyen, Huanjun Lu, Hyesu Kim

Publikováno v: J Clin Invest

The baroreceptor reflex is a powerful neural feedback that regulates arterial pressure (AP). Mechanosensitive channels transduce pulsatile AP to electrical signals in baroreceptors. Here we show that tentonin 3 (TTN3/TMEM150C), a cation channel activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8de3b85dc3907d85db5c72b9a74df29
https://doi.org/10.1172/jci133798

Tentonin 3/TMEM150c, a mechanotransduction channel for arterial pressure sensing baroreceptors

Autor: Jae Hyouk Choi, Jungwon Wee, Gyu-Sang Hong, Uhtaek Oh, H. J. Kim, Thien-Luan Nguyen, Sungmin Pak, Huanjun Lu, Hyesu Kim

Publikováno v: IBRO Reports. 6:S303

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab26188159d2e85ede695aad4cce919c
https://doi.org/10.1016/j.ibror.2019.07.939

Tentonin 3/TMEM150C senses blood pressure changes in the aortic arch.

Autor: Huan-Jun Lu^1,2, Thien-Luan Nguyen^1,2, Gyu-Sang Hong¹, Sungmin Pak¹, Hyesu Kim¹, Hyungsup Kim¹, Dong-Yoon Kim³, Sung-Yon Kim³, Yiming Shen⁴, Pan Dong Ryu⁴, Mi-Ock Lee², Uhtaek Oh¹ utoh@kist.re.kr, Lu, Huan-Jun^5,6 (AUTHOR), Nguyen, Thien-Luan^5,6 (AUTHOR), Hong, Gyu-Sang⁵ (AUTHOR), Pak, Sungmin⁵ (AUTHOR), Kim, Hyesu⁵ (AUTHOR), Kim, Hyungsup⁵ (AUTHOR), Kim, Dong-Yoon⁷ (AUTHOR), Kim, Sung-Yon⁷ (AUTHOR)

Publikováno v: Journal of Clinical Investigation. Jul2020, Vol. 130 Issue 7, p3671-3683. 13p.

Case Report: Pre- and postnatal management of an allantoic cyst with patent urachus and single umbilical artery.

Autor: Trong Thach T; University of Medicine and Pharmacy, Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam ; Hung Vuong Hospital, Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam., Duy Quan V; University of Medicine and Pharmacy, Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam., Diem Nghi T; School of Medicine, Vietnam National University, Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam., Hoang Anh N; School of Medicine, Vietnam National University, Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam., Phi Hung L; University of Medicine and Pharmacy, Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam., Thien Luan N; University of Medicine and Pharmacy, Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam., Phuoc Long N; University of Medicine and Pharmacy, Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam.

Publikováno v: F1000Research [F1000Res] 2015 May 22; Vol. 4, pp. 124. Date of Electronic Publication: 2015 May 22 (Print Publication: 2015).