Výsledky vyhledávání - "Thiemann, Patricia"

Akademický článek

mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft

Autor: Ramaswamy Krishna, Toleno Donna M, Dranchak Patricia K, Ma Xuan, Thiemann Patricia, Prescott Julia, Lecane Philip, Magda Darren, Siegmund Kimberly D, Hacia Joseph G

Publikováno v: BMC Genomics, Vol 9, Iss 1, p 521 (2008)

Abstract Background Interactions between the gene products encoded by the mitochondrial and nuclear genomes play critical roles in eukaryotic cellular function. However, the effects mitochondrial DNA (mtDNA) levels have on the nuclear transcriptome h

Externí odkaz: https://doaj.org/article/6d2e19a3055a4d9dac70ca4519314b4f

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Akademický článek

Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression

Autor: Pike Brian L, Sessler Jonathan L, Cho Dong-Gyu, Magda Darren, Miller Richard A, Naumovski Louie, Miles Dale, Tonev Danielle, Ma Xuan, Cortez Cecilia, Fan Qing, Thiemann Patricia, Lecane Philip S, Wang Zhong, Yeligar Samantha M, Karaman Mazen W, Hacia Joseph G

Publikováno v: Molecular Cancer, Vol 6, Iss 1, p 9 (2007)

Abstract Background Sapphyrin analogues and related porphyrin-like species have attracted attention as anticancer agents due to their selective localization in various cancers, including hematologic malignancies, relative to surrounding tissues. Sapp

Externí odkaz: https://doaj.org/article/f0f518eff0774a25ae7ce8e7b63087ab

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