The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation.

Autor: de Boer EC; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands.; Department of Pediatric Immunology, Rheumatology, and Infectious Diseases, Emma Children's Hospital Amsterdam University Medical Centre Amsterdam The Netherlands., Thielen AJ; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands., Langereis JD; Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences Radboudumc Nijmegen The Netherlands.; Radboud Center for Infectious Diseases, Radboudumc Nijmegen The Netherlands., Kamp A; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands., Brouwer MC; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands., Oskam N; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands., Jongsma ML; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands., Baral AJ; Translational and Clinical Research Institute Newcastle upon Tyne UK., Spaapen RM; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands., Zeerleder S; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands.; Department of Hematology, Luzerner Kantonsspital Luzern and University of Bern Bern Switzerland.; Department for BioMedical Research University of Bern Bern Switzerland., Vidarsson G; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory Amsterdam University Medical Center Amsterdam The Netherlands., Rispens T; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands., Wouters D; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands.; Centre for Infectious Disease Control National Institute for Public Health and the Environment (RIVM) Bilthoven The Netherlands., Pouw RB; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands.; Sanquin Health Solutions Amsterdam The Netherlands., Jongerius I; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Amsterdam Infection and Immunity Institute, Amsterdam University Medical Centre Amsterdam The Netherlands.; Department of Pediatric Immunology, Rheumatology, and Infectious Diseases, Emma Children's Hospital Amsterdam University Medical Centre Amsterdam The Netherlands.

Publikováno v: Clinical & translational immunology [Clin Transl Immunology] 2023 Jan 27; Vol. 12 (1), pp. e1436. Date of Electronic Publication: 2023 Jan 27 (Print Publication: 2023).