Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thidarat, Wongpinyochit"'
Publikováno v:
Nanoscale Advances
Silk is now making inroads into advanced pharmaceutical and biomedical applications. Both bottom-up and top-down approaches can be applied to silk and the resulting aqueous silk solution can be processed into a range of material formats, including na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52284c6719f53399b1cdaff21744b8cf
https://doi.org/10.1039/c8na00208h
https://doi.org/10.1039/c8na00208h
Publikováno v:
ACS biomaterials scienceengineering. 4(3)
Silk nanoparticles are viewed as promising vectors for intracellular drug delivery as they can be taken up into cells by endocytosis and trafficked to lysosomes, where lysosomal enzymes and the low pH trigger payload release. However, the subsequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22dbe5fa54990d5c9c0408ee0370337c
https://pubmed.ncbi.nlm.nih.gov/33418776
https://pubmed.ncbi.nlm.nih.gov/33418776
Autor:
John D. Totten, Alastair J. Florence, F. Philipp Seib, Jana I. Solomun, Thidarat Wongpinyochit
Publikováno v:
ACS Biomaterials Science & Engineering
Silk has a long track record of clinical use in the human body, and new formulations, including silk nanoparticles, continue to reveal the promise of this natural biopolymer for healthcare applications. Native silk fibroin can be isolated directly fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6804832839fcee65d83546b2054dc3b
https://strathprints.strath.ac.uk/72052/7/Solomun_etal_ACSBSE_2020_Manual_versus_microfluidic_assisted_nanoparticle_manufacture.pdf
https://strathprints.strath.ac.uk/72052/7/Solomun_etal_ACSBSE_2020_Manual_versus_microfluidic_assisted_nanoparticle_manufacture.pdf
Autor:
Thidarat Wongpinyochit, Sukriti Gupta, F. Philipp Seib, Samir H. Mushrif, Blair F. Johnston, Antony D. Vassileiou
Publikováno v:
The journal of physical chemistry letters. 10(15)
Silk continues to amaze: over the past decade, new research threads have emerged that include the use of silk fibroin for advanced pharmaceutics, including its suitability for drug delivery. Despite this ongoing interest, the details of silk fibroin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b406d69b597b67d89ff17ae6ef9ae5f5
https://pubmed.ncbi.nlm.nih.gov/31318218
https://pubmed.ncbi.nlm.nih.gov/31318218
Silk fibroin nanoparticles are emerging as promising nanomedicines, but their full therapeutic potential is yet to be realized. These nanoparticles can be readily PEGylated to improve colloidal stability and to tune degradation and drug release profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169525b511bb5e39b8ddd2ce7da4a057
http://hdl.handle.net/10773/36154
http://hdl.handle.net/10773/36154
Autor:
Manfred F, Maitz, Claudia, Sperling, Thidarat, Wongpinyochit, Manuela, Herklotz, Carsten, Werner, F Philipp, Seib
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 13(8)
Many nanoparticles are designed for use as potential nanomedicines for parenteral administration. However, emerging evidence suggests that hemocompatibility is important, but is highly particle- and test-bed dependent. Thus, knowledge of bulk materia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2e0ecce60ed31e08f1b08ab42325ee5
https://pubmed.ncbi.nlm.nih.gov/28757180
https://pubmed.ncbi.nlm.nih.gov/28757180
Silk nanoparticles are expected to improve chemotherapeutic drug targeting to solid tumours by exploiting tumour pathophysiology, modifying the cellular pharmacokinetics of the payload and ultimately resulting in trafficking to lysosomes and triggeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872809f62982e5bb2f96a560802a4d1e
Autor:
Raquel, Saborano, Thidarat, Wongpinyochit, John D, Totten, Blair F, Johnston, F Philipp, Seib, Iola F, Duarte
Publikováno v:
Advanced healthcare materials. 6(14)
Monitoring macrophage metabolism in response to nanoparticle exposure provides new insights into biological outcomes, such as inflammation or toxicity, and supports the design of tailored nanomedicines. This paper describes the metabolic signature of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b09cbad1220b4a7a3359f8fe710b8bb
https://pubmed.ncbi.nlm.nih.gov/28544603
https://pubmed.ncbi.nlm.nih.gov/28544603
Silk is a promising biopolymer for biomedical and pharmaceutical applications due to its outstanding mechanical properties, biocompatibility and biodegradability, as well its ability to protect and subsequently release its payload in response to a tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db1b6a5cd982191cb432ca55c88a849
https://strathprints.strath.ac.uk/56695/7/Wongpinyochit_Seib_JOVE_2016_Manufacture_and_drug_delivery_applications_of_silk.pdf
https://strathprints.strath.ac.uk/56695/7/Wongpinyochit_Seib_JOVE_2016_Manufacture_and_drug_delivery_applications_of_silk.pdf
Publikováno v:
Nanoscale Advances; Feb2019, Vol. 1 Issue 2, p873-883, 11p