Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thibaut Gelé"'
Autor:
Thibaut Gelé, Hélène Gouget, Nathalie Dereuddre-Bosquet, Valérie Furlan, Roger Le Grand, Olivier Lambotte, Delphine Desjardins, Aurélie Barrail-Tran
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2282 (2022)
The development of animal models undergoing long-term antiretroviral treatment (ART) makes it possible to understand a number of immunological, virological, and pharmacological issues, key factors in the management of HIV infection. We aimed to pharm
Externí odkaz:
https://doaj.org/article/c22b7677f8bc4894bae9d1f72940c31a
Autor:
Nicolas Vignal, Salvatore Cisternino, Nathalie Rizzo-Padoin, Carine San, Fortune Hontonnou, Thibaut Gelé, Xavier Declèves, Laure Sarda-Mantel, Benoît Hosten
Publikováno v:
Molecules, Vol 23, Iss 6, p 1375 (2018)
[18F]FEPPA is a specific ligand for the translocator protein of 18 kDa (TSPO) used as a positron emission tomography (PET) biomarker for glial activation and neuroinflammation. [18F]FEPPA radiosynthesis was optimized to assess in a mouse model the ce
Externí odkaz:
https://doaj.org/article/6c022df3b6dc4d96916ae1308821b191
Autor:
Laura Labarthe, Thibaut Gelé, Hélène Gouget, Mariam-Sarah Benzemrane, Pauline Le Calvez, Nicolas Legrand, Olivier Lambotte, Roger Le Grand, Christine Bourgeois, Aurélie Barrail-Tran
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1094-1101
Background Studies of antiretroviral drug (ARV) tissue distribution in preclinical models, such as mice, are key to understanding viral persistence. Objectives To determine the plasma and tissue pharmacokinetics and tissue distributions of tenofovir,
Autor:
Jacques Gasnault, Pierre-Hadrien Becker, Lionelle Nkam, Antoine Cheret, Anne-Marie Taburet, Aurélie Barrail-Tran, Valérie Furlan, Pilartxo Catalan, Cécile Goujard, Thibaut Gelé, Hélène Gouget, Coralie Pallier, Alicia Castro Gordon
Publikováno v:
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, 2021, 76 (12), pp.3280-3285. ⟨10.1093/jac/dkab334⟩
Journal of Antimicrobial Chemotherapy, 2021, 76 (12), pp.3280-3285. ⟨10.1093/jac/dkab334⟩
Objectives The penetration of antiretroviral drugs into deep compartments, such as the CNS, is a crucial component of strategies towards an HIV cure. This study aimed to determine CSF concentrations of bictegravir, emtricitabine and tenofovir in pati
Effect of high-dose rifampicin on efavirenz pharmacokinetics: drug–drug interaction randomized trial
Autor:
Daniel, Atwine, Elisabeth, Baudin, Thibaut, Gelé, Winnie, Muyindike, Kenneth, Mworozi, Racheal, Kyohairwe, Keneth, Kananura, Patrick, Orikiriza, Dan, Nyehangane, Deborah, K T Nanjebe, Valérie, Furlan, Céline, Verstuyft, Aurélie, Barrail-Tran, Anne-Marie, Taburet, Maryline, Bonnet, P, Justumus
Publikováno v:
Journal of Antimicrobial Chemotherapy. 75:1250-1258
We regret that this article is behind a paywall.
Background: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown. Objectives: To assess the effect of doubling the rifamp
Background: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown. Objectives: To assess the effect of doubling the rifamp
Autor:
Hélène Gouget, Anne-Marie Taburet, Aurélie Barrail-Tran, Thibaut Gelé, Pierre-Hadrien Becker, Olivier Lambotte, Valérie Furlan
Publikováno v:
Antimicrob Agents Chemother
This study aimed to characterize in vitro dolutegravir (DTG) and bictegravir (BIC) binding. They had a preferential binding to human serum albumin (HSA) with two classes of albumin sites. Human alpha-1-acid glycoprotein (HAAG) binding of DTG and BIC
Autor:
Thibaut Gelé, Christophe Duvoux, Anne Marie Taburet, Didier Samuel, Carole Cagnot, Claire Laforest, Christophe Moreno, Valérie Canva, H. Danjou, Georges-Philippe Pageaux, Victor de Lédinghen, Danielle Botta-Fridlund, Nassim Kamar, Audrey Lavenu, Lauriane Goldwirt, Sylvie Radenne, Claire Fougerou-Leurent, Filomena Conti, François Durand, Aurélie Barrail-Tran, Vincent Leroy, Louis d’Alteroche, Jean-Charles Duclos-Vallée, Pauline Houssel-Debry, Audrey Coilly
Publikováno v:
European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology, Springer Verlag, 2019, 75 (11), pp.1555-1563. ⟨10.1007/s00228-019-02725-x⟩
European Journal of Clinical Pharmacology, 2019, 75 (11), pp.1555-1563. ⟨10.1007/s00228-019-02725-x⟩
European Journal of Clinical Pharmacology, Springer Verlag, 2019, 75 (11), pp.1555-1563. ⟨10.1007/s00228-019-02725-x⟩
European Journal of Clinical Pharmacology, 2019, 75 (11), pp.1555-1563. ⟨10.1007/s00228-019-02725-x⟩
Purpose: Direct-acting antiviral agents have demonstrated their efficacy in treating HCV recurrence after liver transplantation and particularly the sofosbuvir/daclatasvir combination. Pharmacokinetic data on both calcineurin inhibitors and direct-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13aa7f616ff462a2ef655639da25a3eb
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02280498
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02280498
Autor:
Thibaut Gelé, A. Schweitzer Chaput, S. Raspaud, A. Destable Nicolau, P. Leclerc, E. Durand, S. Marie
Publikováno v:
Médecine Nucléaire. 43:212
Introduction Le [18F]-FDG est le medicament radiopharmaceutique le plus utilise en medecine nucleaire pour la TEP. Celui-ci est commande chaque jour pour etre livre pluri-quotidiennement le lendemain en flacons multidoses selon la planification des p
Autor:
Benoit Hosten, Xavier Declèves, Nathalie Rizzo-Padoin, Thibaut Gelé, Carine San, Nicolas Vignal, Salvatore Cisternino, Fortune Hontonnou, Laure Sarda-Mantel
Publikováno v:
Molecules
Molecules, MDPI, 2018, 23 (6), pp.1375. ⟨10.3390/molecules23061375⟩
Molecules, Vol 23, Iss 6, p 1375 (2018)
Volume 23
Issue 6
Molecules, MDPI, 2018, 23 (6), pp.1375. ⟨10.3390/molecules23061375⟩
Molecules, Vol 23, Iss 6, p 1375 (2018)
Volume 23
Issue 6
[18F]FEPPA is a specific ligand for the translocator protein of 18 kDa (TSPO) used as a positron emission tomography (PET) biomarker for glial activation and neuroinflammation. [18F]FEPPA radiosynthesis was optimized to assess in a mouse model the ce
Autor:
C. Pallier, P.-H. Becker, Aurélie Barrail-Tran, Antoine Cheret, V. Furlan, J. Gasnault, Cécile Goujard, Anne-Marie Taburet, Thibaut Gelé
Publikováno v:
Médecine et Maladies Infectieuses. 48:S152
Introduction La diffusion des antiretroviraux les plus recents au niveau du systeme nerveux central (SNC) n’est pas completement caracterisee. L’objectif de cette etude est de caracteriser la diffusion au niveau du liquide cerebrospinal (LCS) du