Zirconium-Catalyzed Hydroalumination of C═O Bonds: Site-Selective De

Autor: Thibaut, Courant, Marine, Gavel, Romain M Q, Renard, Vincent, Gandon, Antoine Y P, Joosten, Thomas, Lecourt

Publikováno v: The Journal of organic chemistry. 86(14)

An unprecedented hydroalumination of C ═ O bonds catalyzed by zirconocene dichloride is reported herein and applied to the site-selective deprotection of peracetylated functional substrates. A mixed metal hydride, with 1:1 zirconium/aluminum stoich

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a419cfa9e52909f1ca2d7a3567137dda
https://pubmed.ncbi.nlm.nih.gov/34125557

Tritylium assisted iodine catalysis for the synthesis of unsymmetrical triarylmethanes

Autor: Luc Neuville, Thibaut Courant, Dina Boyarskaya, Marine Lombard, Géraldine Masson

Publikováno v: Organic and Biomolecular Chemistry
Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2020, 18 (33), pp.6502-6508. ⟨10.1039/D0OB01502D⟩

International audience; The combined Lewis acid catalytic system, generated from molecular iodine and tritylium tetrafluoroborate effectively catalyzed the Friedel−Crafts (FC) arylation of diarylmethyl sulfides providing an efficient access to vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0698e3e00870addd98ddd9f930d22904
https://hal.archives-ouvertes.fr/hal-03009611

Electrochemical Intramolecular Oxytrifluoromethylation of N -Tethered Alkenyl Alcohols: Synthesis of Functionalized Morpholines

Autor: Géraldine Masson, Aurélie Claraz, Thibaut Courant

Publikováno v: Organic Letters
Organic Letters, American Chemical Society, 2020, 22 (4), pp.1580-1584. ⟨10.1021/acs.orglett.0c00176⟩

International audience; An electrochemical intramolecular oxytrifluoromethylation of N-tethered alkenyl alcohols was developed providing straightforward access to CF3-containing morpholines derivatives. The method features mild reaction conditions wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94e9fa854445cc0fb4612eb522580d2
https://hal.archives-ouvertes.fr/hal-03058500

Divergent Access to (1,1) and (1,2)‐Azidolactones from Alkenes using Hypervalent Iodine Reagents

Autor: Franck Le Vaillant, Sébastien Alazet, Jerome Waser, Stefano Nicolai, Thibaut Courant

Publikováno v: Chemistry – A European Journal. 23:9501-9504

A versatile synthesis of azidolactones through azidation and cyclization of carboxylic acids onto alkenes has been developed. Based on either photoredox or palladium catalysis, (1,1) and (1,2) azido lactones can be selectively synthesized. The choice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c87c617b2bd83ab42e362b58ab23cb
https://doi.org/10.1002/chem.201702599

Regio- and Chemoselective Deprotection of Primary Acetates by Zirconium Hydrides

Autor: Thibaut Courant, Marine Gavel, Antoine Joosten, Thomas Lecourt

Publikováno v: Organic Letters
Organic Letters, American Chemical Society, 2019, 21 (7), pp.1948-1952. ⟨10.1021/acs.orglett.8b03947⟩

International audience; A combination of DIBAL-H and Cp2ZrCl2 is shown to promote the regioselective cleavage of primary acetates on a broad scope of substrates, ranging from carbohydrates to terpene derivatives, with a high tolerance toward protecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f0d66a03dc742a511475df18c3c080
https://pubmed.ncbi.nlm.nih.gov/30848922