Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Thibault Lagache"'
Autor:
Alison Hanson, Raphael Reme, Noah Telerman, Wataru Yamamoto, Jean-Christophe Olivo-Marin, Thibault Lagache, Rafael Yuste
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The ability to record every spike from every neuron in a behaving animal is one of the holy grails of neuroscience. Here, we report coming one step closer towards this goal with the development of an end-to-end pipeline that automatically tr
Externí odkaz:
https://doaj.org/article/7ed8df33156b42bdb39368c4bb5b7ac4
Autor:
Fanny Momboisse, Giacomo Nardi, Philippe Colin, Melanie Hery, Nelia Cordeiro, Simon Blachier, Olivier Schwartz, Fernando Arenzana-Seisdedos, Nathalie Sauvonnet, Jean-Christophe Olivo-Marin, Bernard Lagane, Thibault Lagache, Anne Brelot
Publikováno v:
eLife, Vol 11 (2022)
G-protein-coupled receptors (GPCR) are present at the cell surface in different conformational and oligomeric states. However, how these states impact GPCRs biological function and therapeutic targeting remains incompletely known. Here, we investigat
Externí odkaz:
https://doaj.org/article/6ee4f1070d8b415380bac80983845833
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 10, p e1009432 (2021)
Measuring the activity of neuronal populations with calcium imaging can capture emergent functional properties of neuronal circuits with single cell resolution. However, the motion of freely behaving animals, together with the intermittent detectabil
Externí odkaz:
https://doaj.org/article/483f18b75a76401cabb10c2e695825ac
Autor:
Thibault Lagache, Alexandre Grassart, Stéphane Dallongeville, Orestis Faklaris, Nathalie Sauvonnet, Alexandre Dufour, Lydia Danglot, Jean-Christophe Olivo-Marin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Elucidating molecular organisation requires precise localisation and analysis. Here the authors develop SODA software for automatic and quantitative mapping of statistically coupled molecules, and use it to unravel spatial organisation of thousands o
Externí odkaz:
https://doaj.org/article/c72243110cc94c5f96e08005bd345ee6
Autor:
Laetitia Bertot, Alexandre Grassart, Thibault Lagache, Giacomo Nardi, Cyril Basquin, Jean-Christophe Olivo-Marin, Nathalie Sauvonnet
Publikováno v:
Cell Reports, Vol 22, Iss 6, Pp 1574-1588 (2018)
Summary: Eukaryotic cells internalize cargos specifically through clathrin-mediated endocytosis (CME) or clathrin-independent endocytosis (CIE). EndophilinA2 was shown as preferentially implicated in CIE, although initially involved in CME. Here, we
Externí odkaz:
https://doaj.org/article/b311a659ff4b45c3bc3a84b86609a419
Autor:
Ming Yuan Li, Marc Grandadam, Kevin Kwok, Thibault Lagache, Yu Lam Siu, Jing Shu Zhang, Kouxiong Sayteng, Mateusz Kudelko, Cheng Feng Qin, Jean-Christophe Olivo-Marin, Roberto Bruzzone, Pei Gang Wang
Publikováno v:
Cell Reports, Vol 10, Iss 9, Pp 1496-1507 (2015)
Membrane receptors at the surface of target cells are key host factors for virion entry; however, it is unknown whether trafficking and secretion of progeny virus requires host intracellular receptors. In this study, we demonstrate that dengue virus
Externí odkaz:
https://doaj.org/article/1f10df79f76c4dbf8d70c39eba0d85b8
Publikováno v:
Frontiers in Physics, Vol 5 (2017)
Influenza viruses enter the cell inside an endosome. During the endosomal journey, acidification triggers a conformational change of the virus spike protein hemagglutinin (HA) that results in escape of the viral genome from the endosome into the cyto
Externí odkaz:
https://doaj.org/article/abf1b5b3c1824e8f92b729aac2b6b13a
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80914 (2013)
One major question in molecular biology is whether the spatial distribution of observed molecules is random or organized in clusters. Indeed, this analysis gives information about molecules' interactions and physical interplay with their environment.
Externí odkaz:
https://doaj.org/article/c8496786488e430a9ac3bb1bc47504a6
Autor:
Fanny Momboisse, Giacomo Nardi, Philippe Colin, Melany Hery, Nelia Cordeiro, Olivier Schwartz, Nathalie Sauvonnet, Fernando Arenzana-Seisdedos, Thibault Lagache, Bernard Lagane, Jean-Christophe Olivo-Marin, Anne Brelot
G protein-coupled receptors (GPCR) are present at the cell surface in different conformational and oligomeric states. However, how these states impact GPCRs biological function and therapeutic targeting remains incompletely known. Here, we investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3111e97b9e5735a051e44532ac402920
https://hal-pasteur.archives-ouvertes.fr/pasteur-03699186
https://hal-pasteur.archives-ouvertes.fr/pasteur-03699186
Publikováno v:
IEEE Transactions on Image Processing
IEEE Transactions on Image Processing, 2020, 30, pp.386-401. ⟨10.1109/TIP.2020.3036759⟩
IEEE Transactions on Image Processing, 2020, 30, pp.386-401. ⟨10.1109/TIP.2020.3036759⟩
International audience; Detection and analysis of informative keypoints is a fundamental problem in image analysis and computer vision. Keypoint detectors are omnipresent in visual automation tasks, and recent years have witnessed a significant surge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e06be46f40b215558e50ac9d582b53d
https://doi.org/10.1109/tip.2020.3036759
https://doi.org/10.1109/tip.2020.3036759