Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Thibault Coursindel"'
Autor:
Alison M Blain, Elizabeth Greally, Graham McClorey, Raquel Manzano, Corinne A Betts, Caroline Godfrey, Liz O'Donovan, Thibault Coursindel, Mike J Gait, Matthew J Wood, Guy A MacGowan, Volker W Straub
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198897 (2018)
Cardiac failure is a major cause of mortality in patients with Duchenne muscular dystrophy (DMD). Antisense-mediated exon skipping has the ability to correct out-of-frame mutations in DMD to produce truncated but functional dystrophin. Traditional an
Externí odkaz:
https://doaj.org/article/3ba329284b914067ab2dc83073aab5b6
Autor:
Thomas C Roberts, K Emelie M Blomberg, Graham McClorey, Samir EL Andaloussi, Caroline Godfrey, Corinne Betts, Thibault Coursindel, Michael J Gait, CI Edvard Smith, Matthew JA Wood
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
MicroRNAs (miRNAs) are a class of small RNAs that regulate gene expression and are implicated in wide-ranging cellular processes and pathological conditions including Duchenne muscular dystrophy (DMD). We have compared differential miRNA expression i
Externí odkaz:
https://doaj.org/article/e9477d02be4e40489e38f8dbfc780860
Autor:
Corinne Betts, Amer F Saleh, Andrey A Arzumanov, Suzan M Hammond, Caroline Godfrey, Thibault Coursindel, Michael J Gait, Matthew JA Wood
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Antisense oligonucleotides (AOs) are currently the most promising therapeutic intervention for Duchenne muscular dystrophy (DMD). AOs modulate dystrophin pre-mRNA splicing, thereby specifically restoring the dystrophin reading frame and generating a
Externí odkaz:
https://doaj.org/article/bbb94f06c18043ce89b202330292cdea
Autor:
Peter Järver, Thibault Coursindel, Samir EL Andaloussi, Caroline Godfrey, Matthew JA Wood, Michael J Gait
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Externí odkaz:
https://doaj.org/article/26969c85402d4af882438039e0d79a44
Autor:
Gilles Ferry, Jean A. Boutin, Aude Kreiter, Karine Puget, Magali Jullian, Thibault Coursindel, Marine Bacchi, Olivier Nosjean, Benjamin Fould, Amélie Maurras
Publikováno v:
Analytical Biochemistry. 519:57-70
Ubiquitin, a 76 amino acid protein, is a key component that contributes to cellular protein homeostasis. The specificity of this modification is due to a series of enzymes: ligases, attaching the ubiquitin to a lysine, and deubiquitinases, which remo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa132d37c16b365d04c942bf15a45c1
https://doi.org/10.1016/j.ab.2016.12.014
https://doi.org/10.1016/j.ab.2016.12.014
Autor:
Raquel Manzano, A. Blain, M J Gait, Matthew J.A. Wood, Caroline Godfrey, Liz O'Donovan, Volker Straub, Corinne A. Betts, Guy A. MacGowan, Thibault Coursindel, E. Greally, Graham McClorey
Publikováno v:
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
PLoS ONE
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
PLoS ONE, Vol 13, Iss 6, p e0198897 (2018)
Universidad de Zaragoza
PLoS ONE
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
PLoS ONE, Vol 13, Iss 6, p e0198897 (2018)
Cardiac failure is a major cause of mortality in patients with Duchenne muscular dystrophy (DMD). Antisense-mediated exon skipping has the ability to correct out-of-frame mutations in DMD to produce truncated but functional dystrophin. Traditional an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0064f88864f9bd6698fc46ff73137357
https://ora.ox.ac.uk/objects/uuid:82754937-7621-4b3b-ac0f-6698b4717eab
https://ora.ox.ac.uk/objects/uuid:82754937-7621-4b3b-ac0f-6698b4717eab
Publikováno v:
Nucleic Acid Therapeutics. 22:71-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7243d953498a4cdcd7e6bee81ab7756c
https://doi.org/10.1089/nat.2012.0341
https://doi.org/10.1089/nat.2012.0341
Autor:
Pascale Zimmermann, Xavier Morelli, Yves Collette, Stefan T. Arold, Javier Perez, Xiaoli Shi, Eric Madore, Sandrine Opi, Thibault Coursindel, Mingdong Huang, Jacques Corbeil, Isabelle Parrot, Audrey Restouin, Adrien Lugari
Publikováno v:
Biochemical Journal. 431:93-102
SFKs (Src family kinases) are central regulators of many signalling pathways. Their functions are tightly regulated through SH (Src homology) domain-mediated protein–protein interactions. A yeast two-hybrid screen using SH3 domains as bait identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cb89eae8f0a6d7d3bf409194dbc9c3
https://doi.org/10.1042/bj20100314
https://doi.org/10.1042/bj20100314
Publikováno v:
Tetrahedron Letters. 49:906-909
The unexpected reactivity of 2,5-diketopiperazines under basic conditions, thanks to N -Boc activation, allows access to valuable pharmacological scaffolds, such as original statine derivatives. Toward this transannular rearrangement of activated lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a1e46075b828d02a026d12abd62ffed
https://doi.org/10.1016/j.tetlet.2007.11.159
https://doi.org/10.1016/j.tetlet.2007.11.159
Autor:
Alejandra Castillo Alvarez, Bernard Lebleu, Sarah Gauck, Taavi Lehto, Prisca Boisguerin, Michael J. Gait, Matthew J.A. Wood, Thibault Coursindel
Publikováno v:
Nucleic Acids Research
Cell-penetrating peptide-mediated delivery of phosphorodiamidate morpholino oligomers (PMOs) has shown great promise for exon-skipping therapy of Duchenne Muscular Dystrophy (DMD). Pip6a-PMO, a recently developed conjugate, is particularly efficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7608a77dde2154184557b442b878b937
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/38019
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/38019