Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor

Autor: Graeme Milligan, Sunil K. Pandey, Brian D. Hudson, Amanda E. Mackenzie, Irina G. Tikhonova, Elisabeth Christiansen, Hannah Murdoch, Maria E Due-Hansen, Trond Ulven, Anna Mette Hansen, Richard J. Ward, Rudi Marquez

Publikováno v: The Journal of Biological Chemistry
Hudson, B D, Due-Hansen, M E, Christiansen, E, Hansen, A M, Mackenzie, A E, Murdoch, H, Pandey, S K, Ward, R J, Marquez, R, Tikhonova, I G, Ulven, T & Milligan, G 2013, ' Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor ', Journal of Biological Chemistry, vol. 288, no. 24, pp. 17296-17312 . https://doi.org/10.1074/jbc.M113.455337
Hudson, B D, Due-Hansen, M E, Christiansen, E, Hansen, A, Mackenzie, A E, Murdoch, H, Pandey, S K, Ward, R J, Marquez, R, Tikhonova, I G, Ulven, T & Milligan, G 2013, ' Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor ', Journal of Biological Chemistry, vol. 288, pp. 17296-17312 . https://doi.org/10.1074/jbc.M113.455337

Background: Understanding the function of FFA2 has been slowed by a lack of selective orthosteric ligands. Results: Residues within FFA2 that dictate the recognition and function of potent and selective orthosteric agonists are described. Conclusion:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc95593b410c8497ec6ceed8e3f6d972
https://pubmed.ncbi.nlm.nih.gov/23589301

Bacterial siderophores: the solution stoichiometry and coordination of the Fe(III) complexes of pyochelin and related compounds

Autor: Tseng, C. F., Burger, A., Mislin, G. L., Schalk, I. J., Yu, S. S., Chan, S. I., Abdallah, M. A.

Publikováno v: Journal of Biological Inorganic Chemistry
Journal of Biological Inorganic Chemistry, Springer Verlag, 2006, 11, pp.419-32

0949-8257 (Print) Journal Article; Pyochelin, its analog 3''-nor-NH-pyochelin, and the related methyl hydroxamate, 2-(2'-hydroxyphenyl)-4,5-dihydrothiazol-4-carboxylic acid methoxymethyl amide, have been prepared together with their Fe(III) complexes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bf52574bc3baf166af05f357e4040cc3
https://hal.archives-ouvertes.fr/hal-00129998

[Studies on the synthesis of the 2-aminothiazole derivatives. IV. Reaction of the 1,1'-dithiodiformamidine hydrohalide with the ketones].

Autor: TAJIKA Y

Publikováno v: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan [Yakugaku Zasshi] 1961 Oct; Vol. 81, pp. 1456-9.

[Studies on thiazole derivatives as analytical reagents. V. 4,4'-Bithiazole derivatives].

Autor: UNO T, AKIHAMA S, ASAKAWA K

Publikováno v: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan [Yakugaku Zasshi] 1962 Feb; Vol. 82, pp. 257-60.

A new development in the formation reaction of thiazolidines from 2-aminolkanethiols and carbonyl compounds.

Autor: TAGUCHI T, TAKATORI T, KOJIMA M

Publikováno v: Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 1962 Mar; Vol. 10, pp. 245-6.