Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Thian Kheoh"'
Autor:
Pasi A. Jänne, Gregory J. Riely, Shirish M. Gadgeel, Rebecca S. Heist, Sai-Hong I. Ou, Jose M. Pacheco, Melissa L. Johnson, Joshua K. Sabari, Konstantinos Leventakos, Edwin Yau, Lyudmila Bazhenova, Marcelo V. Negrao, Nathan A. Pennell, Jun Zhang, Kenna Anderes, Hirak Der-Torossian, Thian Kheoh, Karen Velastegui, Xiaohong Yan, James G. Christensen, Richard C. Chao, Alexander I. Spira
Publikováno v:
New England Journal of Medicine. 387:120-131
Autor:
Charles J. Ryan, Howard I. Scher, Dana E. Rathkopf, Kathy Zelinsky, Deborah S. Ricci, Thian Kheoh, Thomas W. Griffin, Arturo Molina, Weimin Li, Alfons J.M. van den Eertwegh, Dirk Schrijvers, Anthony M. Joshua, Som D. Mukherjee, Karim Fizazi, Christopher J. Logothetis, Johann S. de Bono, Gerhardt Attard
Supplementary Table 3. PSA decline by ERG class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961c474b4e59492a9f2a56eac0e00443
https://doi.org/10.1158/1078-0432.22459962
https://doi.org/10.1158/1078-0432.22459962
Autor:
Stephen R.D. Johnston, Peter De Porre, Kathy Zelinsky, Michael Schaffer, Jason Martin, Michael Gormley, Margaret Yu, Thian Kheoh, Thomas Griffin, Deborah Ricci, Patrick Neven, Marie-Pascale Graas, Olga Ivanova, Marina Stenina, Etienne Brain, Irina Zbarskaya, Igor Bondarenko, Mario Campone, Daniel Hayes, Joyce O'Shaughnessy, Weimin Li
Purpose: Abiraterone may suppress androgens that stimulate breast cancer growth. We conducted a biomarker analysis of circulating tumor cells (CTCs), formalin-fixed paraffin-embedded tissues (FFPETs), and serum samples from postmenopausal estrogen re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6df31c489c09b0ccfa55dcb8a8af70
https://doi.org/10.1158/1078-0432.c.6524609.v1
https://doi.org/10.1158/1078-0432.c.6524609.v1
Autor:
Charles J. Ryan, Howard I. Scher, Dana E. Rathkopf, Kathy Zelinsky, Deborah S. Ricci, Thian Kheoh, Thomas W. Griffin, Arturo Molina, Weimin Li, Alfons J.M. van den Eertwegh, Dirk Schrijvers, Anthony M. Joshua, Som D. Mukherjee, Karim Fizazi, Christopher J. Logothetis, Johann S. de Bono, Gerhardt Attard
Supplementary Figure 4. ERG FISH break apart assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6d5a204e619703e6caefd0dfdeca0b
https://doi.org/10.1158/1078-0432.22459971
https://doi.org/10.1158/1078-0432.22459971
Autor:
Charles J. Ryan, Howard I. Scher, Dana E. Rathkopf, Kathy Zelinsky, Deborah S. Ricci, Thian Kheoh, Thomas W. Griffin, Arturo Molina, Weimin Li, Alfons J.M. van den Eertwegh, Dirk Schrijvers, Anthony M. Joshua, Som D. Mukherjee, Karim Fizazi, Christopher J. Logothetis, Johann S. de Bono, Gerhardt Attard
Supplementary Table 1. Demographics and baseline characteristics by ERG class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3722b15d6d2f4b93ff5d9e541d5406c2
https://doi.org/10.1158/1078-0432.22459968
https://doi.org/10.1158/1078-0432.22459968
Autor:
Stephen R.D. Johnston, Peter De Porre, Kathy Zelinsky, Michael Schaffer, Jason Martin, Michael Gormley, Margaret Yu, Thian Kheoh, Thomas Griffin, Deborah Ricci, Patrick Neven, Marie-Pascale Graas, Olga Ivanova, Marina Stenina, Etienne Brain, Irina Zbarskaya, Igor Bondarenko, Mario Campone, Daniel Hayes, Joyce O'Shaughnessy, Weimin Li
Supplementary Table S1. Biomarkers evaluated Supplementary Table S2. Additional biomarker associations with PFS by treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a84f83dc1ce974ceb2f8767e3a481e0
https://doi.org/10.1158/1078-0432.22460840
https://doi.org/10.1158/1078-0432.22460840
Autor:
Charles J. Ryan, Howard I. Scher, Dana E. Rathkopf, Kathy Zelinsky, Deborah S. Ricci, Thian Kheoh, Thomas W. Griffin, Arturo Molina, Weimin Li, Alfons J.M. van den Eertwegh, Dirk Schrijvers, Anthony M. Joshua, Som D. Mukherjee, Karim Fizazi, Christopher J. Logothetis, Johann S. de Bono, Gerhardt Attard
Purpose: Gene fusions leading to androgen receptor–modulated ERG overexpression occur in up to 70% of metastatic castration-resistant prostate cancers (mCRPC). We assessed the association between ERG rearrangement status and clinical benefit from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb62fe791cbcdf4eef4f79d30be7792
https://doi.org/10.1158/1078-0432.c.6524364
https://doi.org/10.1158/1078-0432.c.6524364
Autor:
Charles J. Ryan, Howard I. Scher, Dana E. Rathkopf, Kathy Zelinsky, Deborah S. Ricci, Thian Kheoh, Thomas W. Griffin, Arturo Molina, Weimin Li, Alfons J.M. van den Eertwegh, Dirk Schrijvers, Anthony M. Joshua, Som D. Mukherjee, Karim Fizazi, Christopher J. Logothetis, Johann S. de Bono, Gerhardt Attard
Supplementary Table 2. Radiographic progression-free survival and overall survival by ERG class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc2ef805c6a12774b36c5aab7e6f8bf
https://doi.org/10.1158/1078-0432.22459965
https://doi.org/10.1158/1078-0432.22459965
Autor:
Stephen R.D. Johnston, Peter De Porre, Kathy Zelinsky, Michael Schaffer, Jason Martin, Michael Gormley, Margaret Yu, Thian Kheoh, Thomas Griffin, Deborah Ricci, Patrick Neven, Marie-Pascale Graas, Olga Ivanova, Marina Stenina, Etienne Brain, Irina Zbarskaya, Igor Bondarenko, Mario Campone, Daniel Hayes, Joyce O'Shaughnessy, Weimin Li
Supplementary Figure S1. Comparison of associations of the negative expression of androgen receptor (AR) (< 10%) with progression-free survival (PFS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01097156985fab26199f58bed7a82d84
https://doi.org/10.1158/1078-0432.22460837
https://doi.org/10.1158/1078-0432.22460837
Autor:
Rona Yaeger, Jared Weiss, Meredith S. Pelster, Alexander I. Spira, Minal Barve, Sai-Hong I. Ou, Ticiana A. Leal, Tanios S. Bekaii-Saab, Cloud P. Paweletz, Grace A. Heavey, James G. Christensen, Karen Velastegui, Thian Kheoh, Hirak Der-Torossian, Samuel J. Klempner
Publikováno v:
N Engl J Med
BACKGROUND: Adagrasib, an oral small-molecule inhibitor of mutant KRAS G12C protein, has shown clinical activity in pretreated patients with several tumor types, including colorectal cancer. Preclinical studies suggest that combining a KRAS G12C inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24015fad60764f1a91e6bb23f76efc78
https://europepmc.org/articles/PMC9908297/
https://europepmc.org/articles/PMC9908297/