Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Thiamine transport"'
Autor:
Aurora Mazzeo, Linda Bellucci, Massimo Porta, Elena Beltramo, Marina Trento, Gabriella Gruden, Federica Barutta
Publikováno v:
Biomedicines, Vol 9, Iss 385, p 385 (2021)
Biomedicines
Volume 9
Issue 4
Biomedicines
Volume 9
Issue 4
Thiamine helps transketolase in removing toxic metabolites, counteracting high glucose-induced damage in microvascular cells, and progression of diabetic retinopathy/nephropathy in diabetic animals. Diabetic subjects show reduced thiamine levels. Hyp
Publikováno v:
Biochemistry (Moscow). 84:829-850
Thiamine (vitamin B1) is a precursor of the well-known coenzyme of central metabolic pathways thiamine diphosphate (ThDP). Highly intense glucose oxidation in the brain requires ThDP-dependent enzymes, which determines the critical significance of th
Autor:
Laura Martí-Sánchez, Belén Pérez-Dueñas, Heidy Baide-Mairena, Anna Marcé-Grau, Juan Darío Ortigoza-Escobar
Publikováno v:
Journal of Inherited Metabolic Disease. 42:581-597
Thiamine is a crucial cofactor involved in the maintenance of carbohydrate metabolism and participates in multiple cellular metabolic processes within the cytosol, mitochondria, and peroxisomes. Currently, four genetic defects have been described cau
Autor:
Jaeah Kim, Michael G. Bartlett, Bradley S. Hanberry, Long H. Dang, Jason Zastre, Shivani Khatu, Hunter C. Jonus, Hendrik Luesch
Publikováno v:
Oncotarget
Supplemental levels of vitamin B1 (thiamine) have been implicated in tumor progression. Tumor cells adaptively up-regulate thiamine transport during hypoxic stress. Upon uptake, thiamine pyrophosphokinase-1 (TPK1) facilitates the rapid phosphorylatio
Autor:
Derrick Chatad, Marina Sirota, Kathleen M. Giacomini, Huy X. Ngo, Sook Wah Yee, Megan L. Koleske, Osatohanmwen J. Enogieru, Bianca Vora
Publikováno v:
The AAPS journal, vol 23, iss 2
The AAPS Journal
The AAPS Journal
A rare cause of megaloblastic anemia (MA) is thiamine-responsive megaloblastic anemia (TRMA), a genetic disorder caused by mutations in SLC19A2 (encoding THTR1), a thiamine transporter. The study objectives were to (1) functionally characterize selec
Autor:
Michael Ott, Ursula Werneke
Publikováno v:
Therapeutic Advances in Psychopharmacology
Therapeutic Advances in Psychopharmacology, Vol 10 (2020)
Therapeutic Advances in Psychopharmacology, Vol 10 (2020)
Wernicke’s encephalopathy (WE) is an acute neuropsychiatric state. Untreated, WE can lead to coma or death, or progress to Korsakoff syndrome (KS) – a dementia characterized by irreversible loss of anterograde memory. Thiamine (vitamin B1) defici
Publikováno v:
Annals of Punjab Medical College. 14
Roger syndrome (Thiamin Responsive Megaloblastic Anemia Syndrome), is characterized by megaloblastic anemia, deafness and diabetes mellitus. It is an autosomal recessive disorder due to mutation in SLC 19A2 gene that leads to defective thiamine trans
Publikováno v:
Diabetes & Vascular Disease Research
Thiamine prevents high glucose-induced damage in microvasculature, and progression of retinopathy and nephropathy in diabetic animals. Impaired thiamine availability causes renal damage in diabetic patients. Two single-nucleotide polymorphisms in SLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9b62a39d7f290f787e9dd1079243e6
http://hdl.handle.net/2318/1715614
http://hdl.handle.net/2318/1715614
Thiamine (vitamin B1) and its phosphorylated precursors are necessary for decarboxylation reactions required in carbohydrate and branched chain amino acid metabolism. Due to its critical roles in central metabolism, thiamine is essential for human an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60e24923624bcfbb0f220ff1f8c6bb8
Autor:
Zhenyao Huang, Yufeng Qin, Xiumei Han, Chuncheng Lu, Minjian Chen, Mingming Yu, Guizhen Du, Yun Fan, Ruohan Wang, Qiaoqiao Xu, Xinru Wang, Xiuzhu Li, Yan Zhang, Yankai Xia
Publikováno v:
J Hazard Mater
Di-(2-ethylhexyl)-phthalate (DEHP) is a ubiquitous environmental pollutant and is widely used in industrial plastics. However, the long-term health implications of prenatal exposure to DEHP remains unclear. We set out to determine whether prenatal DE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611a25216cf4a7c39d68ff9cfddbac51
https://europepmc.org/articles/PMC7220048/
https://europepmc.org/articles/PMC7220048/