Zobrazeno 1 - 10
of 306
pro vyhledávání: '"Thiago S, Moreira"'
Publikováno v:
Experimental Physiology, Vol 109, Iss 11, Pp 1837-1843 (2024)
Abstract At least four mechanisms have been proposed to elucidate how neurons in the retrotrapezoid (RTN) region sense changes in CO2/H+ to regulate breathing (i.e., function as respiratory chemosensors). These mechanisms include: (1) intrinsic neuro
Externí odkaz:
https://doaj.org/article/103fef083f814eb282d57d762242af60
Autor:
Nicole C. Miranda, Luiz M. Oliveira, Thiago S. Moreira, Jan-Marino Ramirez, Franck Kalume, Ana C. Takakura
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111251- (2024)
Summary: Parkinson’s disease (PD) is a chronic neurodegenerative disorder affecting the motor system, with non-classic symptoms such as sleep disturbances and respiratory dysfunctions. These issues reflect a complex pathophysiological interaction t
Externí odkaz:
https://doaj.org/article/891b542b86734eda80eeba574fe02211
Autor:
Luiz M. Oliveira, Silvio A. Fernandes-Junior, Laís M.C. Cabral, Nicole C.S. Miranda, Catherine M. Czeisler, José J. Otero, Thiago S. Moreira, Ana C. Takakura
Publikováno v:
Brain Research Bulletin, Vol 187, Iss , Pp 138-154 (2022)
Parkinson’s disease (PD) patients often experience impairment of autonomic and respiratory functions. These include conditions such as orthostatic hypotension and sleep apnea, which are highly correlated with dysfunctional central chemoreception. B
Externí odkaz:
https://doaj.org/article/f362ce827d3540d08d3926560929ba38
Autor:
Caroline B Ferreira, Talita M Silva, Phelipe E Silva, Claudio L Castro, Catherine Czeisler, José J Otero, Ana C Takakura, Thiago S Moreira
Publikováno v:
eLife, Vol 11 (2022)
Mutations in the transcription factor Phox2b cause congenital central hypoventilation syndrome (CCHS). The syndrome is characterized by hypoventilation and inability to regulate breathing to maintain adequate O2 and CO2 levels. The mechanism by which
Externí odkaz:
https://doaj.org/article/507e8eb3bee8488b9368b47ae8f36d0e
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/412f7709e3fe4c9f80028691d6ffe40d
Autor:
João A. B. Pedroso, Ivson B. da Silva, Thais T. Zampieri, Leonardo T. Totola, Thiago S. Moreira, Ana P. T. Taniguti, Gabriela P. Diniz, Maria Luiza M. Barreto-Chaves, Jose Donato
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6484 (2022)
Leptin resistance is a hallmark of obesity. Treatments aiming to improve leptin sensitivity are considered a promising therapeutical approach against obesity. However, leptin receptor (LepR) signaling also modulates several neurovegetative aspects, s
Externí odkaz:
https://doaj.org/article/1ebc96f0690649ecbcbd7de84212cb6a
Publikováno v:
Neuroscience. 512:32-46
Autor:
Colin M Cleary, Thiago S Moreira, Ana C Takakura, Mark T Nelson, Thomas A Longden, Daniel K Mulkey
Publikováno v:
eLife, Vol 9 (2020)
Respiratory chemoreceptors regulate breathing in response to changes in tissue CO2/H+. Blood flow is a fundamental determinant of tissue CO2/H+, yet little is known regarding how regulation of vascular tone in chemoreceptor regions contributes to res
Externí odkaz:
https://doaj.org/article/9ff7d9f1713040c0874ea849ac4d4a7e
Publikováno v:
eLife, Vol 9 (2020)
Breathing results from the interaction of two distinct oscillators: the pre-Bötzinger Complex (preBötC), which drives inspiration; and the lateral parafacial region (pFRG), which drives active expiration. The pFRG is silent at rest and becomes rhyt
Externí odkaz:
https://doaj.org/article/8767b11fb23c4eb4aab1a705ddf6a7b8
Autor:
Yingtang Shi, Cleyton R. Sobrinho, Jaseph Soto‐Perez, Brenda M. Milla, Daniel S. Stornetta, Ruth L. Stornetta, Ana C. Takakura, Daniel K. Mulkey, Thiago S. Moreira, Douglas A. Bayliss
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
A brainstem homeostatic system senses CO