Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Thiago Martino"'
Autor:
Pítia Flores Ledur, Karina Karmirian, Carolina da Silva Gouveia Pedrosa, Leticia Rocha Quintino Souza, Gabriela Assis-de-Lemos, Thiago Martino Martins, Jéssica de Cassia Cavalheiro Gomes Ferreira, Gabriel Ferreira de Azevedo Reis, Eduardo Santos Silva, Débora Silva, José Alexandre Salerno, Isis Moraes Ornelas, Sylvie Devalle, Rodrigo Furtado Madeiro da Costa, Livia Goto-Silva, Luiza Mendonça Higa, Adriana Melo, Amilcar Tanuri, Leila Chimelli, Marcos Massao Murata, Patrícia Pestana Garcez, Eduardo Cremonese Filippi-Chiela, Antonio Galina, Helena Lobo Borges, Stevens Kastrup Rehen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Zika virus (ZIKV) has been extensively studied since it was linked to congenital malformations, and recent research has revealed that astrocytes are targets of ZIKV. However, the consequences of ZIKV infection, especially to this cell type,
Externí odkaz:
https://doaj.org/article/9e62ed1ee57742299fe776937168f5bf
Autor:
Thiago Martino Martins
Publikováno v:
Biblioteca Digital de Teses e Dissertações da UERJUniversidade do Estado do Rio de JaneiroUERJ.
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Tem sido descrito que o acúmulo de mutações em proto-oncogenes e genes supressores de tumor contribui para o direcionamento da célula à carcinogênese. Na maioria dos casos de
Tem sido descrito que o acúmulo de mutações em proto-oncogenes e genes supressores de tumor contribui para o direcionamento da célula à carcinogênese. Na maioria dos casos de
Autor:
Thiago, Martino, Graziele Freitas, DE Bem, Shirley Vania Moura, Santos, Marsen Garcia Pinto, Coelho, Angela DE Castro, Resende, Chaquip, Netto, Paulo Roberto Ribeiro, Costa, Graça, Justo, Katia Costa DE Carvalho, Sabino
Publikováno v:
Anticancer Research. 43:359-367
Prostate cancer (PCa) is one of the most common malignancies in adult men. LQB-118 is a pterocarpanquinone with antitumor activity toward prostate cancer cells. It inhibits cell proliferation by down-regulating cyclins D1 and B1 and up-regulating p21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e2abbe110892bd689983210e35a909
https://doi.org/10.21873/anticanres.16171
https://doi.org/10.21873/anticanres.16171
Autor:
Rachell R C Thimoteo, Tatiana de Almeida Simão, Débora S.S. Costa, Thiago Martino, Kátia Costa de Carvalho Sabino, Paulo R. R. Costa, Julio C. F. Barcellos, Marsen Garcia Pinto Coelho, Ayres G. Dias, Graça Justo
Publikováno v:
Anticancer research. 41(10)
Background/aim A new set of LQB-nitrones and analogues was synthesized to evaluate anticancer activity based on the substitution of the terpenyl moiety of the antileukemic compound LQB-278 by the conformationally restricted cinnamyl ether. Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36eacc046df882a6b3c851606ae72d0c
https://pubmed.ncbi.nlm.nih.gov/34593440
https://pubmed.ncbi.nlm.nih.gov/34593440
Autor:
Antonio Galina, Patricia P. Garcez, Marcos Massao Murata, Leila Chimelli, Rodrigo Madeiro da Costa, José Alexandre Salerno, Amilcar Tanuri, Karina Karmirian, Eduardo Santos Silva, Gabriela Assis-de-Lemos, Sylvie Devalle, Stevens K. Rehen, Gabriel Ferreira de Azevedo Reis, Helena L. Borges, Livia Goto-Silva, Carolina da S. G. Pedrosa, Débora Pedroza Guedes da Silva, Luiza M. Higa, Eduardo C. Filippi-Chiela, Leticia R. Q. Souza, Pítia Flores Ledur, Isis M. Ornelas, Thiago Martino Martins, Adriana Suely de Oliveira Melo, Jéssica de Cassia Cavalheiro Gomes Ferreira
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Zika virus (ZIKV) has been extensively studied since it was linked to congenital malformations, and recent research has revealed that astrocytes are targets of ZIKV. However, the consequences of ZIKV infection, especially to this cell type, remain la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c064895c5601f4689092824284be013d
https://doi.org/10.1038/s41598-020-57914-x
https://doi.org/10.1038/s41598-020-57914-x
Akademický článek
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Autor:
Isabel Vieira da Silva, Livia Casanova, Gleison Freitas, Thiago Martino, Monica Pereira, Fernanda Pereira dos Santos, Katia de Carvalho Sabino, Sônia Costa
Publikováno v:
Current Traditional Medicine. 1:203-216
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::230d5c8fa55302ffb15f10f348559f66
https://doi.org/10.2174/221508380103151231152219
https://doi.org/10.2174/221508380103151231152219
Autor:
Graça Justo, Paulo R. R. Costa, Marsen Garcia Pinto Coelho, Victor B. Moura, Julio C. F. Barcellos, Kátia Costa de Carvalho Sabino, Fernanda Cândido Magalhães, Ayres G. Dias, Débora S.S. Costa, Thiago Martino
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:2053-2061
New O-isoprenylated-N-methylarylnitrones derived from isomeric o, m and p-hydroxybenzaldehydes have been prepared and the antineoplastic effects on human cancer cell lines were evaluated. The O-geranylated nitrone LQB-278 (1b) and its isomers 2b and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf35c9b5f19bceac21dd0e4388254f67
https://doi.org/10.1016/j.bmc.2015.03.014
https://doi.org/10.1016/j.bmc.2015.03.014
Autor:
Fabiana A Pinto, Ana Paula S. Azevedo, Kátia Costa de Carvalho Sabino, Wanderson S Pereira, Flávia R.F. Nascimento, Daniele Corrêa Fernandes, Elyzabeth Avvad Portari, Marsen Garcia Pinto Coelho, Nathalia Regina F Leal, Leosvaldo S. M. Velozo, Shirley Vânia Moura Santos, Johnny R. Nascimento, Girlaine Pereira da Silva, Eduardo Nunes da Fonseca, Mariana Vieira Vigliano, Lauro R Souza Neto, Thiago Martino, F.F. Bastos
Publikováno v:
The Journal of pharmacy and pharmacology. 70(8)
Objectives To evaluate the effect of hydroalcoholic crude extract (HCE) from Chenopodium ambrosioides leaves on the development of type II collagen-induced arthritis (CIA) and on pro-inflammatory cytokine balance. Methods Collagen-induced arthritis w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc17facf2fbe46cd1890b470f4e9450
https://pubmed.ncbi.nlm.nih.gov/29708588
https://pubmed.ncbi.nlm.nih.gov/29708588
Autor:
Shawn E. Lupold, Paulo R. R. Costa, Tarana A. Kudrolli, Andre Luiz Mencalha, Marsen Garcia Pinto Coelho, Thiago Martino, Graça Justo, Ísis Salviano, Kátia Costa de Carvalho Sabino, Binod Kumar
Publikováno v:
The Prostate. 78(2)
Background The targeted induction of reactive oxygen species (ROS) is a developing mechanism for cancer therapy. LQB-118 is a pterocarpanquinone and ROS-inducing agent with proven antineoplastic activity. Here, LQB-118 efficacy and mechanism of activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e23810a8bf2c69b407c5ccfe3ffc0c5
https://pubmed.ncbi.nlm.nih.gov/29105806
https://pubmed.ncbi.nlm.nih.gov/29105806