Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Thiago M, Steiner"'
Autor:
Lauren E. Holz, Julia E. Prier, David Freestone, Thiago M. Steiner, Kieran English, Darryl N. Johnson, Vanessa Mollard, Anton Cozijnsen, Gayle M. Davey, Dale I. Godfrey, Katsuyuki Yui, Laura K. Mackay, Mireille H. Lahoud, Irina Caminschi, Geoffrey I. McFadden, Patrick Bertolino, Daniel Fernandez-Ruiz, William R. Heath
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 68-79.e4 (2018)
Summary: Liver tissue-resident memory T (Trm) cells migrate throughout the sinusoids and are capable of protecting against malaria sporozoite challenge. To gain an understanding of liver Trm cell development, we examined various conditions for their
Externí odkaz:
https://doaj.org/article/f5f33bbac9d74ad79fe3d15e26d1c156
Publikováno v:
European Journal of Immunology. 52:189-196
Antibodies are hallmarks of most effective vaccines. For successful T-dependent antibody responses, conventional dendritic cells (cDC) have been largely attributed the role of priming T cells. By contrast, follicular dendritic cells and macrophages h
Autor:
Patrick Schriek, Alan C. Ching, Nagaraj S. Moily, Jessica Moffat, Lynette Beattie, Thiago M. Steiner, Laine M. Hosking, Joshua M. Thurman, V. Michael Holers, Satoshi Ishido, Mireille H. Lahoud, Irina Caminschi, William R. Heath, Justine D. Mintern, Jose A. Villadangos
Publikováno v:
Science. 375
Marginal zone (MZ) B cells produce broad-spectrum antibodies that protect against infection early in life. In some instances, antibody production requires MZ B cells to display pathogen antigens bound to major histocompatibility complex class II (MHC
Autor:
Patrick Bertolino, Anton Cozijnsen, Stephen J. Turner, Mireille H. Lahoud, Daniel Fernandez-Ruiz, Benjamin J. Compton, Matthias H. Enders, Lauren E. Holz, Geoffrey I. McFadden, Kathryn J. Farrand, Kirsteen M. Tullett, Ana Maria Valencia-Hernandez, Juby Mathew, Ian F. Hermans, Taryn L. Osmond, Dale I. Godfrey, William R. Heath, David G. Bowen, Vanessa Mollard, Rose May, Thiago M. Steiner, Zhongfang Wang, Gavin F. Painter, Joshua Lange, Lynette Beattie, Catarina F. Almeida, Lukasz Kedzierski, Sarah L. Draper, Jasmine Li, Susanna T. S. Chan, Maria N. de Menezes, Yu Cheng Chua, Katherine Kedzierska, Irina Caminschi, Sonia Ghilas, Regan J. Anderson, Rebecca Seneviratna
Publikováno v:
Science Immunology. 5
Liver resident-memory CD8+ T cells (TRM cells) can kill liver-stage Plasmodium-infected cells and prevent malaria, but simple vaccines for generating this important immune population are lacking. Here, we report the development of a fully synthetic s
Autor:
William R. Heath, Daniel Fernandez-Ruiz, Laura K. Mackay, Patrick Bertolino, Katsuyuki Yui, Thiago M. Steiner, Geoffrey I. McFadden, Darryl N. Johnson, Julia E. Prier, Anton Cozijnsen, Gayle M. Davey, Vanessa Mollard, Lauren E. Holz, Mireille H. Lahoud, Dale I. Godfrey, David Freestone, Irina Caminschi, Kieran English
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 68-79.e4 (2018)
Summary: Liver tissue-resident memory T (Trm) cells migrate throughout the sinusoids and are capable of protecting against malaria sporozoite challenge. To gain an understanding of liver Trm cell development, we examined various conditions for their
Autor:
Lauren E, Holz, Yu Cheng, Chua, Maria N, de Menezes, Regan J, Anderson, Sarah L, Draper, Benjamin J, Compton, Susanna T S, Chan, Juby, Mathew, Jasmine, Li, Lukasz, Kedzierski, Zhongfang, Wang, Lynette, Beattie, Matthias H, Enders, Sonia, Ghilas, Rose, May, Thiago M, Steiner, Joshua, Lange, Daniel, Fernandez-Ruiz, Ana Maria, Valencia-Hernandez, Taryn L, Osmond, Kathryn J, Farrand, Rebecca, Seneviratna, Catarina F, Almeida, Kirsteen M, Tullett, Patrick, Bertolino, David G, Bowen, Anton, Cozijnsen, Vanessa, Mollard, Geoffrey I, McFadden, Irina, Caminschi, Mireille H, Lahoud, Katherine, Kedzierska, Stephen J, Turner, Dale I, Godfrey, Ian F, Hermans, Gavin F, Painter, William R, Heath
Publikováno v:
Science immunology. 5(48)
Liver resident-memory CD8
Autor:
Ana Maria, Valencia-Hernandez, Wei Yi, Ng, Nazanin, Ghazanfari, Sonia, Ghilas, Maria N, de Menezes, Lauren E, Holz, Cheng, Huang, Kieran, English, Myo, Naung, Peck Szee, Tan, Kirsteen M, Tullett, Thiago M, Steiner, Matthias H, Enders, Lynette, Beattie, Yu Cheng, Chua, Claerwen M, Jones, Anton, Cozijnsen, Vanessa, Mollard, Yeping, Cai, David G, Bowen, Anthony W, Purcell, Nicole L, La Gruta, Jose A, Villadangos, Tania, de Koning-Ward, Alyssa E, Barry, Winfried, Barchet, Ian A, Cockburn, Geoffrey I, McFadden, Stephanie, Gras, Mireille H, Lahoud, Patrick, Bertolino, Ralf B, Schittenhelm, Irina, Caminschi, William R, Heath, Daniel, Fernandez-Ruiz
Publikováno v:
Cell hostmicrobe. 27(6)
Liver-resident memory CD8
Publikováno v:
Current opinion in immunology. 58
B cells are efficiently activated by antigens presented on cell membranes, which provide opportunity for receptor cross-linking and antigen capture. The two main cell types implicated in native antigen presentation to B cells are follicular dendritic
Autor:
Fellype C. Barreto, F. Brehm, Natalia Borges Bonan, Roberto Pecoits-Filho, Thiago M. Steiner, Gabriela Ferreira Dias, Andrea N Moreno-Amaral, Selene Elifio-Esposito, Andréa E.M. Stinghen, Wesley M. Souza, Marina Luise Viola de Azevedo
Publikováno v:
Toxicology Letters. 263:1-5
Immune system dysfunction is a common condition in chronic kidney disease (CKD). The present study investigated the effect of p-Cresyl sulfate (pCS) on human cell line U937 monocyte-derived macrophages (MDM) activity. MDM (1 × 106 cells/mL) were inc
Autor:
Geoffrey I. McFadden, Mireille H. Lahoud, Kieran English, Irina Caminschi, Sonia Ghilas, Maria N. de Menezes, Wei Yi Ng, Thiago M. Steiner, Matthias H. Enders, Patrick Bertolino, Peck Szee Tan, Ana Maria Valencia-Hernandez, Vanessa Mollard, Lauren E. Holz, Nicole L. La Gruta, Anton Cozijnsen, Jose A Villadangos, Yeping Cai, Daniel Fernandez-Ruiz, David G. Bowen, Kirsteen M. Tullett, Ralf B. Schittenhelm, William R. Heath, Lynette Beattie, Tania F. de Koning-Ward, Claerwen M. Jones, Stephanie Gras, Yu Cheng Chua, Alyssa E. Barry, Anthony W. Purcell, Ian A. Cockburn, Winfried Barchet, Cheng Huang, Myo T. Naung, Nazanin Ghazanfari
Publikováno v:
Cell Host & Microbe. 27:950-962.e7
Liver-resident memory CD8+ T (TRM) cells remain in and constantly patrol the liver to elicit rapid immunity upon antigen encounter and can mediate efficient protection against liver-stage Plasmodium infection. This finding has prompted the developmen