Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Thiago C, Elias"'
Publikováno v:
Journal of Computational Chemistry. 39:2481-2487
Bioisosterism is a technique used in medicinal chemistry to optimize lead compounds in drug research. One can replace a substituent group in original molecule by another with similar physical chemistry properties and then test how this replacement af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47f532f5f73a34e295e14dd47d481a84
https://doi.org/10.1002/jcc.25581
https://doi.org/10.1002/jcc.25581
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2053
Docking process is one of the most significant activities for the analysis of protein-protein or protein-ligand complexes. These tools have become of unique importance when allocated in web services, collaborating scientifically with several areas of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4fe8e1a225665b1a7f0c0ea06bee116
https://pubmed.ncbi.nlm.nih.gov/31452108
https://pubmed.ncbi.nlm.nih.gov/31452108
Autor:
Luiz Felipe Leomil Coelho, Thiago dos Santos, Camila de Morais Coelho, Fallon dos Santos Siqueira, Gabriel Augusto Pires de Souza, Marli Matiko Anraku de Campos, Thiago C. Elias, Diogo Teixeira Carvalho, Eloísa Salete Segatto Dalla Nora
Publikováno v:
Journal of the Brazilian Chemical Society.
Eugenol has diverse biological properties including antimycobacterial activity, and the triazole ring is an important heterocycle in antimycobacterial compounds. Therefore, this research aimed to synthesize novel eugenol-derived 1,2,3-triazole as ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fd33ef08988970351dd7be28d69811a
https://doi.org/10.21577/0103-5053.20190038
https://doi.org/10.21577/0103-5053.20190038
Autor:
Daniel de Queiroz Omote, Helen Andrade Arcuri, Icaro Alves Pinto, Thiago C. Elias, Arlindo L. Oliveira, Luciano T. Costa, Tati Ishikawa, Paulo V. S. D. de Carvalho, Walter Filgueira de Azevedo Junior, Susana Vinga, Poliany G. Freitas, Nelson José Freitas da Silveira, Ihosvany Camps
Publikováno v:
Freitas, P G, Elias, T C, Pinto, I A, Costa, L T, de Carvalho, P V S D, Omote, D D Q, Camps, I, Ishikawa, T, Arcuri, H A, Vinga, S, Oliveira, A L, Junior, W F A & da Silveira, N J F 2018, ' Computational approach to the discovery of phytochemical molecules with therapeutic potential targets to the PKCZ protein ', Letters in Drug Design & Discovery, vol. 15, no. 5, pp. 488-499 . https://doi.org/10.2174/1570180814666170810120150
Letters in Drug Design & Discovery
Letters in Drug Design & Discovery
Background: Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignancies in humans and the average 5-year survival rate is one of the lowest among aggressive cancers. Protein kinase C zeta (PKCZ) is highly expressed in head an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1daea79f45d4d1a817b9df2cec5e1801
https://portal.findresearcher.sdu.dk/da/publications/03ebd5d7-a7a0-4bbf-af29-3dca1b3ae9b9
https://portal.findresearcher.sdu.dk/da/publications/03ebd5d7-a7a0-4bbf-af29-3dca1b3ae9b9
