Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Thiéric Rodriguez"'
Autor:
Elsa Pflimlin, Thierry Durroux, Iuliia A. Karpenko, Thiéric Rodriguez, Jean-François Margathe, Elodie Dupuis, Marcel Hibert, Dominique Bonnet
Publikováno v:
Journal of Medicinal Chemistry. 58:2547-2552
The design and the synthesis of the first high-affinity fluorescent ligands for oxytocin receptor (OTR) are described. These compounds enabled the development of a TR-FRET based assay for OTR, readily amenable to high throughput screening. The valida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816e50dbb2308aa241ce336db42b1028
https://doi.org/10.1021/jm501395b
https://doi.org/10.1021/jm501395b
Autor:
Elodie Dupuis, Candide Hounsou, Vincent Gasparik, Jean-Philippe Pin, Denis Heissler, Doria Alili, Abderazak Belhocine, Thierry Durroux, Corinne Baehr, Marcel Hibert, André Mann, Dominique Bonnet, Thomas Roux, Thiéric Rodriguez
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 61 (1), pp.174-188. ⟨10.1021/ACS.JMEDCHEM.7B01220⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 61 (1), pp.174-188. ⟨10.1021/ACS.JMEDCHEM.7B01220⟩
Monoamine neurotransmitters such as serotonin, dopamine, histamine, and noradrenaline have important and varied physiological functions and similar chemical structures. Representing important pharmaceutical drug targets, the corresponding G-protein-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ca155c5fb3560ebce588fcfb140fcf
https://hal.archives-ouvertes.fr/hal-02366277
https://hal.archives-ouvertes.fr/hal-02366277
Autor:
Jean-Philippe Pin, Thierry Durroux, Abderazak Belhocine, Candide Hounsou, Jurriaan M. Zwier, Nadia Oueslati, Thiéric Rodriguez, Elodie Dupuis, Eric Trinquet
Publikováno v:
Methods in Molecular Biology
Methods in Molecular Biology, 1272, pp.23-36, 2015, ⟨10.1007/978-1-4939-2336-6_2⟩
Methods in Molecular Biology ISBN: 9781493923359
Methods in Molecular Biology, 1272, pp.23-36, 2015, ⟨10.1007/978-1-4939-2336-6_2⟩
Methods in Molecular Biology ISBN: 9781493923359
International audience; Screening chemical libraries to find specific drugs for G protein-coupled receptors is still of major interest. Indeed, because of their major roles in all physiological functions, G protein-coupled receptors remain major targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff3f197b106bf82afde41325d31d35a
https://hal.umontpellier.fr/hal-02068533
https://hal.umontpellier.fr/hal-02068533