Recognizing CRISPR as the new age disease-modifying drug: Strategies to bioengineer CRISPR/Cas for direct in vivo delivery.

Autor: Thevendran R; Department of Biotechnology, Faculty of Applied Science, AIMST University, Bedong, Kedah, Malaysia., Maheswaran S; Department of Biotechnology, Faculty of Applied Science, AIMST University, Bedong, Kedah, Malaysia.; Centre of Excellence for Nanotechnology and Nanomedicine (CoExNano), AIMST University, Bedong, Kedah, Malaysia.

Publikováno v: Biotechnology journal [Biotechnol J] 2023 Sep; Vol. 18 (9), pp. e2300077. Date of Electronic Publication: 2023 May 21.

The Diagnostic Potential of RNA Aptamers against the NS1 Protein of Dengue Virus Serotype 2.

Autor: Thevendran R; Department of Biomedical Science, Advanced Medical & Dental Institute (AMDI), University Sains Malaysia, Bertam, Kepala Batas 13200, Malaysia., Rogini S; Department of Biomedical Science, Advanced Medical & Dental Institute (AMDI), University Sains Malaysia, Bertam, Kepala Batas 13200, Malaysia., Leighton G; Hutano Diagnostics Ltd. BioEscalator, Innovation Building, Old Road Campus, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Mutombwera A; Hutano Diagnostics Ltd. BioEscalator, Innovation Building, Old Road Campus, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Shigdar S; School of Medicine, Deakin University, Geelong, VIC 3217, Australia.; Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Deakin University, Geelong, VIC 3220, Australia., Tang TH; Department of Biomedical Science, Advanced Medical & Dental Institute (AMDI), University Sains Malaysia, Bertam, Kepala Batas 13200, Malaysia., Citartan M; Department of Biomedical Science, Advanced Medical & Dental Institute (AMDI), University Sains Malaysia, Bertam, Kepala Batas 13200, Malaysia.

Publikováno v: Biology [Biology (Basel)] 2023 May 15; Vol. 12 (5). Date of Electronic Publication: 2023 May 15.

Reverse Electrochemical Sensing of FLT3-ITD Mutations in Acute Myeloid Leukemia Using Gold Sputtered ZnO-Nanorod Configured DNA Biosensors.

Autor: Thevendran R; Infectomics Cluster, Advanced Medical & Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas 13200, Malaysia., Foo KL; Nano Biochip Research Group, Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, Kangar 01000, Malaysia., Hussin MH; Materials Technology Research Group (MaTReC), School of Chemical Sciences, Universiti Sains Malaysia, Minden 11800, Malaysia., Moses EJ; Regenerative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas 13200, Malaysia., Citartan M; Infectomics Cluster, Advanced Medical & Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas 13200, Malaysia., Prasad HR; Faculty of Engineering and Computer Technology, AIMST University, Semeling 08100, Malaysia., Maheswaran S; Regenerative Medicine Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, Kepala Batas 13200, Malaysia.; Department of Biotechnology, Faculty of Applied Sciences, AIMST University, Bedong 08100, Malaysia.; Centre of Excellence for Nanobiotechnology & Nanomedicine (CoExNano), Faculty of Applied Sciences, AIMST University, Bedong 08100, Malaysia.

Publikováno v: Biosensors [Biosensors (Basel)] 2022 Mar 10; Vol. 12 (3). Date of Electronic Publication: 2022 Mar 10.

In silico molecular docking in DNA aptamer development.

Autor: Navien TN; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia., Thevendran R; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia., Hamdani HY; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia., Tang TH; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia. Electronic address: tangth@usm.my., Citartan M; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia. Electronic address: citartan@usm.my.

Publikováno v: Biochimie [Biochimie] 2021 Jan; Vol. 180, pp. 54-67. Date of Electronic Publication: 2020 Oct 18.

Mathematical approaches in estimating aptamer-target binding affinity.

Autor: Thevendran R; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia., Navien TN; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia., Meng X; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, United States., Wen K; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, United States., Lin Q; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, United States., Sarah S; School of Medicine, Deakin University, Pigdons Road, Waurn Ponds, Victoria, 3216, Australia., Tang TH; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia. Electronic address: tangth@usm.my., Citartan M; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Penang, Malaysia; Department of Mechanical Engineering, Columbia University, New York, NY, 10027, United States. Electronic address: citartan@usm.my.

Publikováno v: Analytical biochemistry [Anal Biochem] 2020 Jul 01; Vol. 600, pp. 113742. Date of Electronic Publication: 2020 Apr 18.