Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Thet Tun Aung"'
Autor:
Peiying Ho, Linh Chi Dam, Wei Ren Ryanna Koh, Rui Si Nai, Qian Hui Nah, Faeqa Binte Muhammad Rajaie Fizla, Chia Ching Chan, Thet Tun Aung, Shin Giek Goh, You Fang, Zhining Lim, Ming Guang Koh, Michael Demott, Yann Felix Boucher, Benoit Malleret, Karina Yew-Hoong Gin, Peter Dedon, Wilfried Moreira
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7009 (2024)
Multidrug-resistant P. aeruginosa infections pose a serious public health threat due to the rise in antimicrobial resistance. Phage therapy has emerged as a promising alternative. However, P. aeruginosa has evolved various mechanisms to thwart phage
Externí odkaz:
https://doaj.org/article/72c7435ff1e94de6ab5702d26dc7d8a2
Autor:
Darren Shu Jeng Ting, Eunice Tze Leng Goh, Venkatesh Mayandi, Joanna M. F. Busoy, Thet Tun Aung, Mercy Halleluyah Periayah, Mario Nubile, Leonardo Mastropasqua, Dalia G. Said, Hla M. Htoon, Veluchamy Amutha Barathi, Roger W. Beuerman, Rajamani Lakshminarayanan, Imran Mohammed, Harminder S. Dua
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Bacterial keratitis (BK) is a major cause of corneal blindness globally. This study aimed to develop a novel class of antimicrobial therapy, based on human-derived hybrid host defense peptides (HyHDPs), for treating BK. HyHDPs were rationall
Externí odkaz:
https://doaj.org/article/b8964e8c144045dd99c424d45d86d9a4
Autor:
Venkatesh Mayandi, Wen-Tyng Kang, Darren Shu Jeng Ting, Eunice Tze Leng Goh, Myoe Naing Lynn, Thet Tun Aung, Jamuna Vadivelu, Veluchamy Amutha Barathi, Anita Sook Yee Chan, Rajamani Lakshminarayanan
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1044 (2023)
The effectiveness of current antifungal therapies is hampered by the emergence of drug resistance strains, highlighting an urgent need for new alternatives such as adjuvant antifungal treatments. This study aims to examine the synergism between propr
Externí odkaz:
https://doaj.org/article/343ac341d3614defaaa57811714693e2
Autor:
Mingjun Yuan, Song Lin Chua, Yang Liu, Daniela I. Drautz-Moses, Joey Kuok Hoong Yam, Thet Tun Aung, Roger W. Beuerman, May Margarette Santillan Salido, Stephan C. Schuster, Choon-Hong Tan, Michael Givskov, Liang Yang, Thomas E. Nielsen
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 3059-3069 (2018)
Antibiotic resistance threatens effective treatment of microbial infections globally. This situation has spurred the hunt for new antimicrobial compounds in both academia and the pharmaceutical industry. Here, we report how the widely used antitumor
Externí odkaz:
https://doaj.org/article/753a8d0395f842239fb8a40c6d273c36
Autor:
Lei Deng, Lukasz Wojciech, Chin Wen Png, Dorinda Yan Qin Kioh, Yuxiang Gu, Thet Tun Aung, Benoit Malleret, Eric Chun Yong Chan, Guangneng Peng, Yongliang Zhang, Nicholas Robert John Gascoigne, Kevin Shyong Wei Tan
Publikováno v:
Theranostics. 13:1165-1179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3405ac4a74e63e696365d8958b835a
https://doi.org/10.7150/thno.81583
https://doi.org/10.7150/thno.81583
Publikováno v:
The Lancet Microbe.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21f901f9b8b88b5db8e78a0faf30eb2a
https://doi.org/10.1016/s2666-5247(23)00097-6
https://doi.org/10.1016/s2666-5247(23)00097-6
Autor:
Navin Kumar Verma, Si Jia Tan, John Chen, Hanrong Chen, Muhammad Hafiz Ismail, Scott A. Rice, Pablo Bifani, Sukumar Hariharan, Vivek Daniel Paul, Bharathi Sriram, Linh Chi Dam, Chia Ching Chan, Peiying Ho, Boon Chong Goh, Shimin Jasmine Chung, Kenneth Choon Meng Goh, Shu Hua Thong, Andrea Lay-Hoon Kwa, Adam Ostrowski, Thet Tun Aung, Halimah Razali, Shermaine W.Y. Low, Mani Shankar Bhattacharyya, Hemant K. Gautam, Rajamani Lakshminarayanan, Thomas Sicheritz-Pontén, Martha R.J. Clokie, Wilfried Moreira, Maurice Adrianus Monique van Steensel
Publikováno v:
Phage (New Rochelle)
Verma, N K, Tan, S J, Chen, J, Chen, H, Ismail, M H, Rice, S A, Bifani, P, Hariharan, S, Paul, V D, Sriram, B, Dam, L C, Chan, C C, Ho, P, Goh, B C, Chung, S J, Goh, K C M, Thong, S H, Kwa, A L H, Ostrowski, A, Aung, T T, Razali, H, Low, S W Y, Bhattacharyya, M S, Gautam, H K, Lakshminarayanan, R, Sicheritz-Pontén, T, Clokie, M R J, Moreira, W & Van Steensel, M A M 2022, ' InPhocus : Current State and Challenges of Phage Research in Singapore ', PHAGE: Therapy, Applications, and Research, vol. 3, no. 1, pp. 6-11 . https://doi.org/10.1089/phage.2022.29028.nkv
Verma, N K, Tan, S J, Chen, J, Chen, H, Ismail, M H, Rice, S A, Bifani, P, Hariharan, S, Paul, V D, Sriram, B, Dam, L C, Chan, C C, Ho, P, Goh, B C, Chung, S J, Goh, K C M, Thong, S H, Kwa, A L H, Ostrowski, A, Aung, T T, Razali, H, Low, S W Y, Bhattacharyya, M S, Gautam, H K, Lakshminarayanan, R, Sicheritz-Pontén, T, Clokie, M R J, Moreira, W & Van Steensel, M A M 2022, ' InPhocus : Current State and Challenges of Phage Research in Singapore ', PHAGE: Therapy, Applications, and Research, vol. 3, no. 1, pp. 6-11 . https://doi.org/10.1089/phage.2022.29028.nkv
Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage research in Singapore and neighboring countries, Lee Kong Chian School of Medicine, Nanyang Tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04edea808200bf93143c9fecdfabb0ac
https://doi.org/10.1089/phage.2022.29028.nkv
https://doi.org/10.1089/phage.2022.29028.nkv
Autor:
Joey Kuok Hoong Yam, Thet Tun Aung, Song Lin Chua, Yingying Cheng, Gurjeet Singh Kohli, Jianuan Zhou, Florentin Constancias, Yang Liu, Zhao Cai, May Margarette Santillan Salido, Daniela I. Drautz-Moses, Scott A. Rice, Stephan Christoph Schuster, Zhao Zhi Boo, Bin Wu, Staffan Kjelleberg, Tim Tolker-Nielsen, Rajamani Lakshminarayanan, Roger W. Beuerman, Liang Yang, Michael Givskov
Publikováno v:
Infection and immunity, 90 (8)
Yam, J K H, Aung, T T, Chua, S L, Cheng, Y, Kohli, G S, Zhou, J, Constancias, F, Liu, Y, Cai, Z, Salido, M M S, Drautz-Moses, D I, Rice, S A, Schuster, S C, Boo, Z Z, Wu, B, Kjelleberg, S, Tolker-Nielsen, T, Lakshminarayanan, R, Beuerman, R W, Yang, L & Givskov, M 2022, ' Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa ', Infection and Immunity, vol. 90, no. 8 . https://doi.org/10.1128/iai.00061-22
Yam, J K H, Aung, T T, Chua, S L, Cheng, Y, Kohli, G S, Zhou, J, Constancias, F, Liu, Y, Cai, Z, Salido, M M S, Drautz-Moses, D I, Rice, S A, Schuster, S C, Boo, Z Z, Wu, B, Kjelleberg, S, Tolker-Nielsen, T, Lakshminarayanan, R, Beuerman, R W, Yang, L & Givskov, M 2022, ' Elevated c-di-GMP Levels and Expression of the Type III Secretion System Promote Corneal Infection by Pseudomonas aeruginosa ', Infection and Immunity, vol. 90, no. 8 . https://doi.org/10.1128/iai.00061-22
Pseudomonas aeruginosa is generally believed to establish biofilm-associated infections under the regulation of the secondary messenger c-di-GMP. To evaluate P. aeruginosa biofilm physiology during ocular infections, comparative transcriptomic analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faabfddccbc986ff3c6cef4e563402a5
https://hdl.handle.net/10453/164130
https://hdl.handle.net/10453/164130
Autor:
Roger W. Beuerman, Myoe Naing Lynn, Wei Hong Jeff Chor, Donald T.H. Tan, Thet Tun Aung, Anita Sook Yee Chan
Publikováno v:
Eye & Contact Lens
Objectives The purpose of this study was to develop a reproducible preclinical Fusarium solani keratitis model, which would allow comparative testing of currently available antifungals (NATACYN [Alcon, Fort Worth, TX], voriconazole 1%, and amphoteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46977e472ccf54ef6522dda73166c495
https://doi.org/10.1097/icl.0000000000000689
https://doi.org/10.1097/icl.0000000000000689
Autor:
Lei Deng, Lukasz Wojciech, Chin Wen Png, Eileen Yiling Koh, Thet Tun Aung, Dorinda Yan Qin Kioh, Eric Chun Yong Chan, Benoit Malleret, Yongliang Zhang, Guangneng Peng, Nicholas Robert John Gascoigne, Kevin Shyong Wei Tan
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(5)
Background Blastocystis is a common gut protistan parasite in humans and animals worldwide, but its interrelationship with the host gut microbiota and mucosal immune responses remains poorly understood. Different murine models of Blastocystis coloniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd12a20a3c00a577f1cfed771660855f
https://pubmed.ncbi.nlm.nih.gov/35435504
https://pubmed.ncbi.nlm.nih.gov/35435504