Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Theron S. Johnson"'
Autor:
Charlotte Le Cornet, Audrey Y. Jung, Theron S. Johnson, Sabine Behrens, Nadia Obi, Heiko Becher, Jenny Chang-Claude, Renée T. Fortner
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-10 (2023)
Abstract Background Experimental studies suggest a role for osteoprotegerin (OPG) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in mammary tumor development and progression. These biomarkers have been minimally investigated with
Externí odkaz:
https://doaj.org/article/e85bfcb1482e4671a97f8b937299aa6c
Autor:
Solomon A. Sowah, Alessio Milanese, Ruth Schübel, Jakob Wirbel, Ece Kartal, Theron S. Johnson, Frank Hirche, Mirja Grafetstätter, Tobias Nonnenmacher, Romy Kirsten, Marina López-Nogueroles, Agustín Lahoz, Kathrin V. Schwarz, Jürgen G. Okun, Cornelia M. Ulrich, Johanna Nattenmüller, Arnold von Eckardstein, Daniel Müller, Gabriele I. Stangl, Rudolf Kaaks, Tilman Kühn, Georg Zeller
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background The gut microbiota has been suggested to play a significant role in the development of overweight and obesity. However, the effects of calorie restriction on gut microbiota of overweight and obese adults, especially over longer du
Externí odkaz:
https://doaj.org/article/b2a9d6f5ed5d4fb9a3a65f3eb76bef31
Autor:
Charlotte Le Cornet, Britta Walter, Disorn Sookthai, Theron S. Johnson, Tilman Kühn, Ester Herpel, Rudolf Kaaks, Renée T. Fortner
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background Experimental and epidemiological studies demonstrate a role for 27-hydroxycholesterol (27HC) in breast cancer development, though results are conflicting. Cholesterol 27-hydroxylase (CYP27A1) and oxysterol 7-alpha-hydroxylase (CYP
Externí odkaz:
https://doaj.org/article/b5c798c2939f4ad8bfcceba255d1b6df
Autor:
Solomon A. Sowah, Frank Hirche, Alessio Milanese, Theron S. Johnson, Mirja Grafetstätter, Ruth Schübel, Romy Kirsten, Cornelia M. Ulrich, Rudolf Kaaks, Georg Zeller, Tilman Kühn, Gabriele I. Stangl
Publikováno v:
Nutrients, Vol 12, Iss 2, p 452 (2020)
Gut microbial-derived short-chain fatty acids (SCFAs) may regulate energy homeostasis and exert anti-carcinogenic, immunomodulatory and anti-inflammatory effects. Smaller trials indicate that dietary weight loss may lead to decreased SCFA production,
Externí odkaz:
https://doaj.org/article/8afb17b30f30477d8ef540cbc49d8ee2
Autor:
Ruth Schübel, Disorn Sookthai, Judith Greimel, Theron S. Johnson, Mirja E. Grafetstätter, Romy Kirsten, Mario Kratz, Cornelia M. Ulrich, Rudolf Kaaks, Tilman Kühn
Publikováno v:
Nutrients, Vol 11, Iss 3, p 639 (2019)
Smaller cross-sectional studies and bariatric surgery trials suggest that weight loss may change the expression of genes in adipose tissue that have been implicated in the development of metabolic diseases, but well-powered intervention trials are la
Externí odkaz:
https://doaj.org/article/c1e6a2c119d943fab821c46e22bc8a07
Autor:
Alina, Vrieling, Petra, Seibold, Theron S, Johnson, Judith, Heinz, Nadia, Obi, Rudolf, Kaaks, Dieter, Flesch-Janys, Jenny, Chang-Claude
Publikováno v:
International journal of cancer. 134(12)
We previously reported that lower post-diagnostic circulating 25-hydroxyvitamin D [25(OH)D] concentrations were associated with higher risk of overall mortality and distant disease in stage I-IV postmenopausal breast cancer survivors. This associatio
Autor:
Monika, Ettinger, Iris K, Gratz, Christina, Gruber, Cornelia, Hauser-Kronberger, Theron S, Johnson, Karsten, Mahnke, Josef, Thalhamer, Helmut, Hintner, Doris, Peckl-Schmid, Johann W, Bauer
Publikováno v:
Experimental dermatology. 21(5)
Antibodies, specific to murine DEC205, can be used to target antigens to dendritic cells. The immunodominant domain of human type XVII collagen, hNC16A, was fused to this antibody (DEC-hNC16A) and was administered as expression plasmid by gene gun tr
Autor:
Sonja Schallenberg, Sabine Ring, Kurt Schönfeld, Volker Storn, Alexander Enk, Karsten Mahnke, Tanja Bedke, Theron S. Johnson
Publikováno v:
European journal of immunology. 37(8)
Suppressive functions of CD4+CD25+ regulatory T cells (Treg) are mainly studied by their interaction with conventional T cells. However, there is evidence that Treg also interact with antigen-presenting cells (APC), leading to suppression of APC func
Autor:
Volker Storn, Sabine Ring, Sabine Fondel, Alexander Enk, Theron S. Johnson, Katharina Wiedemeyer, Sonja Schallenberg, Karsten Mahnke, Tanja Bedke, Svetlana Karakhanova, Kurt Schönfeld
Publikováno v:
International journal of cancer. 120(12)
The aim of this study was to investigate whether depletion of CD4(+)CD25(+) regulatory T cells (Treg) from melanoma patients affects immune responses against tumors. By application of recombinant IL-2-diphteria toxin fusion protein, also known as ONT
Publikováno v:
Journal of dermatological science. 46(3)
At first glance, dendritic cells (DCs) and regulatory T cells (Tregs) do not have much in common. DCs are characterized by their unsurpassed T cell stimulatory capacity, whereas Tregs are marked by the ability to suppress proliferation of effector T