Výsledky vyhledávání - "Theressa J. Wright"

Prevention of sudden cardiac death in the young: Developing a rational, reliable, and sustainable national health care resource. A report from the Cardiac Safety Research Consortium

Autor: Salim F. Idriss, Theressa J. Wright, Victoria L. Vetter, Stuart Berger, Valarie Morrow, Tess Saarel, Martha Lopez-Anderson, Allen Kindman, Mitchell W. Krucoff, Kimberly G. Harmon, Silvana Molossi, Kaori Shinagawa, Robert Kleiman, Thomas G. Todaro, Colette Strnadova

Publikováno v: American Heart Journal. 190:123-131

This White Paper, prepared by members of the Cardiac Safety Research Consortium, discusses important issues regarding sudden cardiac death in the young (SCDY), a problem that does not discriminate by gender, race, ethnicity, education, socioeconomic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074f19e716a59f3706dc121e15338bca
https://doi.org/10.1016/j.ahj.2017.05.003

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The Cardiac Safety Research Consortium enters its second decade: An invitation to participate

Autor: Peter R. Kowey, Christopher H. Cabell, Barbara Lopez Kunz, J. Rick Turner, Mitchell W. Krucoff, Cynthia L. Green, Ignacio Rodriguez, Norman Stockbridge, John Finkle, Gary Gintant, Theressa J. Wright, Philip T. Sager, Justin Mortara

Publikováno v: American Heart Journal. 177:96-101

The Cardiac Safety Research Consortium (CSRC), a transparent, public-private partnership established in 2005 as a Critical Path Program and formalized in 2006 under a Memorandum of Understanding between the United States Food and Drug Administration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184166c4180d76f59e03920b73d86685
https://doi.org/10.1016/j.ahj.2016.04.009

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Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: Further evidence for survival and safety and implications for early treatment*

Autor: William L. Macias, Mary Ann Turlo, Christopher J. Doig, Christian Putensen, Antonio Artigas, JF Dhainaut, Richard Beale, Kar Wong, Jonathan Janes, Roberto Fumagalli, David P. Sundin, Jean Louis Vincent, Gordon R. Bernard, Theressa J. Wright

Publikováno v: Critical Care Medicine. 33:2266-2277

Objective: To provide further evidence for the efficacy and safety of drotrecogin alfa (activated) treatment in severe sepsis. Design: Single-arm, open-label, trial of drotrecogin alfa (activated) treatment in severe sepsis patients. Enrolment began

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce0529c1d69b8ca76887b83dbce19bf
https://doi.org/10.1097/01.ccm.0000181729.46010.83

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Extended Evaluation of Recombinant Human Activated Protein C United States Trial (ENHANCE US)

Autor: Gordon R. Bernard, Howard Levy, E. Wesley Ely, Harvey M. Shanies, Arthur P. Wheeler, Theressa J. Wright, Benjamin D. Margolis, Kar Wong

Publikováno v: Chest. 125:2206-2216

Study objective To gather additional 28-day all-cause mortality and safety data among adult patients with severe sepsis who were treated with drotrecogin alfa (activated). Design Prospective, single-arm, multicenter clinical trial. Setting Eighty-fiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c79eb9900a458f38e924fee8ecff5e19
https://doi.org/10.1378/chest.125.6.2206

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Adverse mortality effect of central sympathetic inhibition with sustained-release moxonidine in patients with heart failure (MOXCON)

Autor: Jean L. Rouleau, Matthias Straub, Marc A. Pfeffer, Jay N. Cohn, Curtis Wiltse, Norman Sharpe, Karl Swedberg, Theressa J. Wright

Publikováno v: European Journal of Heart Failure. 5:659-667

Background: The association between sympathetic activation and mortality in chronic heart failure and the favorable effect of beta blocking drugs has raised the possibility of therapeutic efficacy for central sympathetic inhibition with sustained-rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f038cfb062284c20a216729c19a1e3
https://doi.org/10.1016/s1388-9842(03)00163-6

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Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis

Autor: Jeffery Helterbrand, Theressa J. Wright, I. Mayers, Peter E. Morris, Eugene Wesley Ely, Jerome Stasek, James A. Russell, S. Yan, Gordon R. Bernard, Joseph Fraiz, Brian A. Rosenfeld

Publikováno v: Critical Care Medicine. 29:2051-2059

Objectives: To assess the safety and effect on coagulopathy of a range of doses of recombinant human activated protein C (rhAPC). To determine an effective dose and duration of rhAPC for use in future clinical trials. Design: Double-blind, randomized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b74fec54436ac3ac97dfd931825fe30
https://doi.org/10.1097/00003246-200111000-00003

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Low Levels of Protein C Are Associated With Poor Outcome in Severe Sepsis

Autor: Theressa J. Wright, Jeffrey D. Helterbrand, Gordon R. Bernard, S. Betty Yan, Daniel L. Hartman

Publikováno v: Chest. 120:915-922

Study objective To investigate whether protein C levels predict 30-day mortality rate, shock status, duration of ICU stay, and ventilator dependence in patients with sepsis. Design Retrospective analysis of a subset of a previously published, prospec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7ca22150276719682dd68e28cb8bd2
https://doi.org/10.1378/chest.120.3.915

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Design and methods of the Raloxifene Use for The Heart (RUTH) study

Autor: Sofia Paul, Elena Moscarelli, Nanette K. Wenger, Jeffrey D. Helterbrand, Lori Mosca, Deborah Grady, Marcel Kornitzer, Elizabeth Barrett-Connor, Theressa J. Wright, Peter Collins, Pamela W. Anderson

Publikováno v: The American Journal of Cardiology. 88:392-395

Raloxifene is a selective estrogen receptor modulator that lowers total and low-density lipoprotein (LDL) cholesterol, reduces the risk of vertebral fracture, and is associated with a reduced incidence of invasive breast cancer in postmenopausal wome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba73f631a41f962c3304b456e85bf4d6
https://doi.org/10.1016/s0002-9149(01)01685-x

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The effects of chronic, sustained-release moxonidine therapy on clinical and neurohumoral status in patients with heart failure

Autor: John McNay, Cord Manhenke, Kenneth Dickstein, Theressa J. Wright, Torbjørn Aarsland, Curtis Wiltse

Publikováno v: International Journal of Cardiology. 75:167-176

Congestive heart failure (CHF) is characterized by elevated plasma norepinephrine (PNE) associated with a poor prognosis. Moxonidine selectively stimulates medullary imidazoline receptors which centrally inhibit sympathetic outflow and potently suppr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b755fffbc6ef40434f85b6d3939773
https://doi.org/10.1016/s0167-5273(00)00319-3

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