Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Therese Wiedmer"'
Autor:
Asma Kassas, Ivan C Moura, Yumi Yamashita, Jorg Scheffel, Claudine Guérin-Marchand, Ulrich Blank, Peter J Sims, Therese Wiedmer, Renato C Monteiro, Juan Rivera, Nicolas Charles, Marc Benhamou
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109800 (2014)
Engagement of high-affinity immunoglobulin E receptors (FcεRI) activates two signaling pathways in mast cells. The Lyn pathway leads to recruitment of Syk and to calcium mobilization whereas the Fyn pathway leads to phosphatidylinositol 3-kinase rec
Externí odkaz:
https://doaj.org/article/ff44d90fc8f940b1aac9aeace16be241
Autor:
Rotem Karni, Mark P. Kamps, Jiaxi Zhou, Sulei Pang, Fei Wang, Hong Yang, Peng Liu, Therese Wiedmer, Dong Li, Qian Zhao, Peter J. Sims, Hong Nan, Yuanfu Xu
Publikováno v:
Blood. 120:4712-4719
Understanding the process of myeloid differentiation offers important insights into both normal and abnormal developmental processes but is limited by the dearth of experimental models. Here we show that myeloid progenitors can be derived from embryo
Publikováno v:
Journal of Leukocyte Biology. 90:221-233
PLSCR1−/− mice exhibit normal, steady-state hematologic parameters but impaired emergency granulopoiesis upon in vivo administration of G-CSF. The mechanism by which PLSCR1 contributes to G-CSF-induced neutrophil production is largely unknown. We
Autor:
Yuji Huang, Zhao Kw, Therese Wiedmer, Peter J. Sims, Qiwu Zhao, Zhimin Gu, Xu Hz, Zhou Cx, Guo-Qiang Chen, Li D
Publikováno v:
Oncogene. 25:6618-6627
Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated protein which is localized in either the cell membrane or nucleus depending on its palmitoylated state. The increasing evidence showed the biological roles of PLSCR1 in cell signaling, ma
Autor:
Wu-Zhong Shen, Peter J. Sims, Zhen-Gang Peng, Xi Li, Guo-Qiang Chen, Ke-Wen Zhao, Dong Li, Zhu Chen, Qian Zhao, Therese Wiedmer, Quansheng Zhou, Ji Zhao, Ying Huang
Publikováno v:
Blood. 104:3731-3738
Although phospholipid scramblase 1 (PLSCR1) was originally identified based on its capacity to promote transbilayer movement of membrane phospholipids, subsequent studies also provided evidence for its role in cell proliferation, maturation, and apop
Autor:
Ji Zhao, Aimin Zhou, Peter J. Sims, Robert H. Silverman, Jeanna Guenther, Roger Slee, Beihua Dong, Ronald N. Harty, Amiya K. Banerjee, Santanu Bose, Therese Wiedmer, Bryan R.G. Williams, Quansheng Zhou
Publikováno v:
Journal of Virology. 78:8983-8993
Interferons (IFNs) are the principal cytokines responsible for mediating innate immunity against viral infections (7). How IFNs establish an antiviral state in cells has been a subject of investigation since their discovery (21). Nevertheless, mechan
Publikováno v:
Journal of Biological Chemistry. 278:37413-37418
Phospholipid scramblase (PLSCR1) is a multiply palmitoylated, calcium-binding endofacial membrane protein proposed to mediate transbilayer movement of plasma membrane phospholipids. PLSCR1 is a component of membrane lipid rafts and has been shown to
Publikováno v:
Biology of Reproduction. 68:2122-2134
Only capacitated sperm cells are able to fertilize egg cells, and this process is triggered by high levels of bicarbonate. Bicarbonate renders the plasma membrane more fluid, which is caused by protein kinase A (PKA)-mediated alterations in the phosp
Publikováno v:
Biochemistry. 42:1227-1233
Phospholipid scramblase 1 (PLSCR1) is a Ca(2+)-binding, endofacial plasma membrane protein thought to contribute to the transbilayer movement of phosphatidylserine and other membrane phospholipids that is observed upon influx of calcium into the cyto
Autor:
Ulrich Blank, Peter J. Sims, Yumi Yamashita, Juan A Rivera, Jörg Scheffel, Claudine Guérin-Marchand, Renato C. Monteiro, Asma Kassas, Ivan C. Moura, Therese Wiedmer, Marc Benhamou, Nicolas Charles
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109800 (2014)
PLoS ONE
PLoS ONE
Engagement of high-affinity immunoglobulin E receptors (FcεRI) activates two signaling pathways in mast cells. The Lyn pathway leads to recruitment of Syk and to calcium mobilization whereas the Fyn pathway leads to phosphatidylinositol 3-kinase rec