Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Therese N. Tripler"'
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss , Pp 222-228 (2020)
From cellular deposition of the HIV-1 capsid to integration of the viral genome, the capsid constitutes a primary target of a variety of host proteins that work to either promote or inhibit HIV-1 infection. Successful progression of HIV-1 infection d
Externí odkaz:
https://doaj.org/article/1dfcd5b2237c4ab384841eb7bc77081f
Publikováno v:
Viruses, Vol 13, Iss 11, p 2242 (2021)
The delivery of the HIV-1 genome into the nucleus is an indispensable step in retroviral infection of non-dividing cells, but the mechanism of HIV-1 nuclear import has been a longstanding debate due to controversial experimental evidence. It was comm
Externí odkaz:
https://doaj.org/article/22794b4332f540ca981914c0430fa18f
Autor:
Min Zhao, Pei-Yi Su, Danielle A Castro, Therese N Tripler, Yingxia Hu, Matthew Cook, Albert I Ko, Shelli F Farhadian, Benjamin Israelow, Charles S Dela Cruz, Yong Xiong, Richard E Sutton, Yale IMPACT Research Team
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009683 (2021)
COVID-19 is a global crisis of unimagined dimensions. Currently, Remedesivir is only fully licensed FDA therapeutic. A major target of the vaccine effort is the SARS-CoV-2 spike-hACE2 interaction, and assessment of efficacy relies on time consuming n
Externí odkaz:
https://doaj.org/article/b2383cfe0cfb49c9beaf80ad8a7fdffc
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss, Pp 222-228 (2020)
Curr Res Struct Biol
Curr Res Struct Biol
From cellular deposition of the HIV-1 capsid to integration of the viral genome, the capsid constitutes a primary target of a variety of host proteins that work to either promote or inhibit HIV-1 infection. Successful progression of HIV-1 infection d
Publikováno v:
Viruses
Viruses, Vol 13, Iss 2242, p 2242 (2021)
Viruses, Vol 13, Iss 2242, p 2242 (2021)
The delivery of the HIV-1 genome into the nucleus is an indispensable step in retroviral infection of non-dividing cells, but the mechanism of HIV-1 nuclear import has been a longstanding debate due to controversial experimental evidence. It was comm
Autor:
Chaoyi Xu, Juan R. Perilla, Sooin Jang, Alan Engelman, Shuai Yuan, Yong Xiong, Swapnil C. Devarkar, Joshua Temple, Chenxiang Lin, Christopher Aiken, Qi Shen, Qiancheng Xiong, Taoran Tian, Therese N. Tripler, Jiong Shi, C. Patrick Lusk, Yingxia Hu, Gregory J. Bedwell
SummaryThe capsid of human immunodeficiency virus 1 (HIV-1) plays a pivotal role in viral nuclear import, but the mechanism by which the viral core passages the nuclear pore complex (NPC) is poorly understood. Here, we use DNA-origami mimics of the N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc52ab90d6bb22c2e2deafac1c62d8f3
https://doi.org/10.1101/2020.08.10.245522
https://doi.org/10.1101/2020.08.10.245522
Publikováno v:
Journal of Virology. 93
Despite very low sequence homology, the major capsid proteins of double-stranded DNA (dsDNA) bacteriophages, some archaeal viruses, and the herpesviruses share a structural motif, the HK97 fold. Bacteriophage P22, a paradigm for this class of viruses
Publikováno v:
Biophysical Journal. 118:23a
Publikováno v:
Biomolecular NMR Assignments. 9:333-336
The P22 bacteriophage group is a subgroup of the λ phage supercluster, comprised of the three major sequence types Sf6, P22, and CUS-3, based on their capsid proteins. Our goal is to investigate the extent to which structure–function relationships
Publikováno v:
Biomolecular NMR assignments. 11(1)
The P22 bacteriophage group is a subgroup of the λ phage supercluster, comprised of the three major sequence types Sf6, P22, and CUS-3, based on their capsid proteins. Our goal is to investigate the extent to which structure–function relationships