Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Therese Juhlin Larsen"'
Autor:
Søren Nielsen, Morten Lundh, Raziel Rojas-Rodriguez, Silvia Corvera, Zinger Yang, Bente Klarlund Pedersen, Anand Desai, Erin L. Brown, Camilla Scheele, Khanh-Van Tran, Tiffany DeSouza, Therese Juhlin Larsen, Qin Yang, Timothy P. Fitzgibbons, Kimberly T. Malka, Anthony M. Mozzicato, Naja Z. Jespersen, Amir Feizi, Hanni Willenbrock, Cecilie Nandrup-Bus, Mai Charlotte Krogh Severinsen, Atul S. Deshmukh, Brice Emanuelli, So Yun Min
Publikováno v:
Nature metabolism
Human thermogenic adipose tissue mitigates metabolic disease, thus raising much interest in understanding its development and function. Here, we show that human thermogenic adipocytes specifically express a primate-specific long noncoding RNA (lncRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850cdf716ed5fab6437b2076fb272475
https://doi.org/10.1038/s42255-020-0205-x
https://doi.org/10.1038/s42255-020-0205-x
Autor:
Tora Ida Henriksen, Ninna S. Hansen, Bente Klarlund Pedersen, Heidi S. Schultz, Maria Pedersen, Camilla Scheele, Therese Juhlin Larsen, Peter K. Davidsen, Allan Vaag, Søren Nielsen
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 7, Pp 770-779 (2017)
Henriksen, T I, Davidsen, P K, Pedersen, M, Schultz, H S, Hansen, N S, Larsen, T J, Vaag, A, Pedersen, B K, Nielsen, S & Scheele, C 2017, ' Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes ', Molecular Metabolism, vol. 6, no. 7, pp. 770-779 . https://doi.org/10.1016/j.molmet.2017.04.006
Molecular Metabolism, Vol 6, Iss 7, Pp 770-779 (2017)
Henriksen, T I, Davidsen, P K, Pedersen, M, Schultz, H S, Hansen, N S, Larsen, T J, Vaag, A, Pedersen, B K, Nielsen, S & Scheele, C 2017, ' Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes ', Molecular Metabolism, vol. 6, no. 7, pp. 770-779 . https://doi.org/10.1016/j.molmet.2017.04.006
Objective MicroRNAs (miRNAs) are increasingly recognized as fine-tuning regulators of metabolism, and are dysregulated in several disease conditions. With their capacity to rapidly change gene expression, miRNAs are also important regulators of devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d729ca494936aa68fc820bd3fd2b66f
https://doi.org/10.1016/j.molmet.2017.04.006
https://doi.org/10.1016/j.molmet.2017.04.006
Autor:
Bente Klarlund Pedersen, Andreas Kjaer, Carsten H. Nielsen, Bhargav S. Prabhakar, Birgitte Holst, Annika Sanfridson, Lone Peijs, Tao Ma, Atul S. Deshmukh, Rafael Bayarri-Olmos, Daniel J. Drucker, Zachary Gerhart-Hines, Therese Juhlin Larsen, Mai Charlotte Krogh Severinsen, Naja Z. Jespersen, Matthias Mann, Jacqueline L. Beaudry, Mads Tang-Christensen, Charlotte Helgstrand, Peter Garred, Andreas D. Brunner, Søren Nielsen, Gilbert G. Privé, Camilla Scheele
Publikováno v:
Cell Metabolism
Summary Adipokines secreted from white adipose tissue play a role in metabolic crosstalk and homeostasis, whereas the brown adipose secretome is less explored. We performed high-sensitivity mass-spectrometry-based proteomics on the cell media of huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa81b49e6c1b2f64413ab6c069ebeb1c
https://pubmed.ncbi.nlm.nih.gov/31668873
https://pubmed.ncbi.nlm.nih.gov/31668873
Publikováno v:
Handbook of experimental pharmacology. 251
Obesity involves a contrasting expansion of the energy-storing white fat and loss of functionally competent brown fat, an energy-consuming thermogenic adipose. Leveraging our understanding of white and brown adipocyte recruitment and investigating fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb27a8918a56017901fba992ff9f068b
https://pubmed.ncbi.nlm.nih.gov/29980911
https://pubmed.ncbi.nlm.nih.gov/29980911
Publikováno v:
Brown Adipose Tissue ISBN: 9783030105129
Obesity involves a contrasting expansion of the energy-storing white fat and loss of functionally competent brown fat, an energy-consuming thermogenic adipose. Leveraging our understanding of white and brown adipocyte recruitment and investigating fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da94040efaf7a95216fb5f326665e749
https://doi.org/10.1007/164_2018_142
https://doi.org/10.1007/164_2018_142
Autor:
Jing Yu, Masayasu Yoneda, Hiroyuki Aburatani, Tomohisa Aoyama, Haruya Ohno, Yu-Hua Tseng, Ryo Nakaki, Ken Suzuki, Naja Z. Jespersen, Masahiro Nakamura, Toshimasa Yamauchi, Takashi Kadowaki, Therese Juhlin Larsen, Yusuke Hirota, Hironori Waki, Wei Sun, Shogo Yamamoto, Yuta Hiraike, Hirofumi Kobayashi, Kana Miyake, Kenji Oki, Andrew P. White, Gaku Nagano, Shuichi Tsutsumi, Aaron M. Cypess, Camilla Scheele
Publikováno v:
Nature cell biology. 19(9)
Brown fat dissipates energy as heat and protects against obesity. Here, we identified nuclear factor I-A (NFIA) as a transcriptional regulator of brown fat by a genome-wide open chromatin analysis of murine brown and white fat followed by motif analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20bb81f8ecf1d5fd61f32a226e315c12
https://pubmed.ncbi.nlm.nih.gov/28812581
https://pubmed.ncbi.nlm.nih.gov/28812581
Publikováno v:
Adipocyte. 3:54-57
There is a current debate in the literature on whether human fat derived from the supraclavicular region should be classified as brown, or as the white fat-derived less potent, brite/beige. This commentary addresses whether the existing classificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2479ae19f6ef7d9c3a164e59b0e8e9e5
https://doi.org/10.4161/adip.26520
https://doi.org/10.4161/adip.26520
Autor:
Naja Z. Jespersen, Barbara Cannon, Jasper M. A. de Jong, Kirsten Møller, Annika Loft, Søren Daugaard, Jan Nedergaard, Lone Peijs, Neha Mathur, Camilla Scheele, Therese Juhlin Larsen, Preben Homøe, Bente Klarlund Pedersen
Publikováno v:
Cell Metabolism. 17(5):798-805
SummaryHuman brown adipose tissue (BAT) has been detected in adults but was recently suggested to be of brite/beige origin. We collected BAT from the supraclavicular region in 21 patients undergoing surgery for suspected cancer in the neck area and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956c4fc4e06df0498908f73636b0c83e
Autor:
Mikael Kronborg Christophersen, Ditte K. Andersen, Finn Cilius Nielsen, Anita Dreher, Maria Rossing, Bodil Norrild, Therese Juhlin Larsen, Bogumil Kaczkowski
Publikováno v:
Biochemical and biophysical research communications. 412(1)
Human papillomaviruses (HPVs) are highly prevalent giving rise to both benign and malignant lesions why they are classified as high- and low-risk viruses. In this study we selected one low-risk (HPV 11) and two high-risk (HPV 16 and -45) types for ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1e7cb9cc24ff87276fd0b05e45c195
https://pubmed.ncbi.nlm.nih.gov/21782796
https://pubmed.ncbi.nlm.nih.gov/21782796
Publikováno v:
Adipocyte; Jan-Mar2014, Vol. 3 Issue 1, p54-57, 4p