Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Therese Buskas"'
Autor:
Therese Buskas, Geert-Jan Boons, Anne E. Boyer, Russell W. Carlson, Maribel Gallegos-Candela, Elke Saile, Elmar L. Kannenberg, John R. Barr, Conrad P. Quinn
Publikováno v:
Clinical and Vaccine Immunology. 18:743-748
TheBacillus anthracisexosporium protein BclA contains an O-linked antigenic tetrasaccharide whose terminal sugar is known as anthrose (J. M. Daubenspeck et al., J. Biol. Chem. 279:30945–30953, 2004). We hypothesized that serologic responses to anth
Publikováno v:
Carbohydrate-Based Vaccines and Immunotherapies
Publikováno v:
ChemBioChem. 9:381-388
A highly convergent strategy was used for the synthesis of a tetrasaccharide [3-aminopropyl beta-L-arabinofuranosyl-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->3)]-alpha-L-arabinopyranoside] portion of the B side chain of th
Autor:
Russell W. Carlson, Geert-Jan Boons, Conrad P. Quinn, Wei Zhong, Alok S. Mehta, Elke Saile, Therese Buskas, Elmar L. Kannenberg, Yvonne Reed
Publikováno v:
Chemistry - A European Journal. 12:9136-9149
The glycoprotein BclA is an important constituent of the exosporium of Bacillus anthracis spores. This glycoprotein is substituted with an oligosaccharide composed of a beta-L-rhamnoside substituted with the previously unknown terminal saccharide, 2-
Publikováno v:
Organic Letters. 8:5785-5788
Although native chemical ligation (NCL) is emerging as a powerful method for the assembly of (glyco)peptide building blocks, its applicability is reduced when peptide segments are poorly soluble in aqueous buffer. We have found that incorporating rea
Publikováno v:
Glycobiology. 16:113R-136R
This review describes the recent advances in the field of glycopeptide and small glycoprotein synthesis. The strategies covered include chemical and chemoenzymatic synthesis, native chemical ligation (NCL), and expressed chemical ligation. The import
Publikováno v:
Journal of Carbohydrate Chemistry. 24:503-516
The activation of 2‐azido‐2‐deoxy Tn and TF thioglycosyl donors by the powerful thiophilic promoter system Ph2SO/Tf2O has been investigated. Glycosylation of an Fmoc‐protected threonine derivative gave 1,2‐cis glycosides in high yields and
Publikováno v:
The Journal of Organic Chemistry. 70:1691-1697
A novel approach for the synthesis of various fragments of proteophosphoglycans from Leishmania major and Leishmania mexicana proteophosphoglycans has been developed. These compounds have been obtained by coupling alpha-mannosyl and alpha-N-acetyl-gl
Publikováno v:
Chemistry - A European Journal. 10:3517-3524
A Lewis(y) (Le(y)) tetrasaccharide modified by an artificial aminopropyl spacer was synthesized by a highly convergent approach that employed a levulinoyl ester and a 9-fluorenylmethoxycarbonate for temporary protection of the hydroxy groups and a tr
Publikováno v:
Journal of Carbohydrate Chemistry. 20:569-583
Di-, tri- and tetramers of β-(1→3)-linked N-acetyllactosamine residues have been synthesised as their methyl glycosides, to be used in ITC binding studies to various galectins. The synthetic strategy involves two types of regioselective glycosylat