Developmental emergence of two-stage nonlinear synaptic integration in cerebellar interneurons

Autor: Celia Biane, Florian Rückerl, Therese Abrahamsson, Cécile Saint-Cloment, Jean Mariani, Ryuichi Shigemoto, David A DiGregorio, Rachel M Sherrard, Laurence Cathala

Publikováno v: eLife, Vol 10 (2021)

Synaptic transmission, connectivity, and dendritic morphology mature in parallel during brain development and are often disrupted in neurodevelopmental disorders. Yet how these changes influence the neuronal computations necessary for normal brain fu

Externí odkaz: https://doaj.org/article/e901c6bb1a0b4100a07a29c39d4e8419

Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling

Autor: Frédéric Charron, Cristian Zaelzer, Gary G. Chen, Charles W. Bourque, P. Jesper Sjöström, Carl Ernst, Jean-François Théroux, Therese Abrahamsson, Blandine Ponroy Bally, Jimmy Peng, Sabrina Chierzi, Christopher Lui, Keith K. Murai, W. Todd Farmer, Emma V. Jones

Publikováno v: Science. 351:849-854

Glial cell properties dictated by neurons Neurons in the brain coexist with astrocytes, a type of glial cell, which help support many functions of their neighboring nerve cells. Farmer et al. now show that the support goes both ways (see the Perspect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8faa8554026c392d7f9b3e4f96331fdd
https://doi.org/10.1126/science.aab3103

ABLE: an Activity-Based Level Set Segmentation Algorithm for Two-Photon Calcium Imaging Data

Autor: P. Jesper Sjöström, Renaud Schuck, Pier Luigi Dragotti, Stephanie Reynolds, Simon R. Schultz, Therese Abrahamsson

Publikováno v: eNeuro

We present an algorithm for detecting the location of cells from two-photon calcium imaging data. In our framework, multiple coupled active contours evolve, guided by a model-based cost function, to identify cell boundaries. An active contour seeks t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af09252d83d46cab6926143d1f18602

Using Multiple Whole-Cell Recordings to Study Spike-Timing-Dependent Plasticity in Acute Neocortical Slices

Autor: Therese Abrahamsson, Txomin Lalanne, P. Jesper Sjöström

Publikováno v: Cold Spring Harbor protocols. 2016(6)

This protocol provides a method for quadruple whole-cell recording to study synaptic plasticity of neocortical connections, with a special focus on spike-timing-dependent plasticity (STDP). It also describes how to morphologically identify recorded c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c021501d8307d6867126eadbbc976381
https://pubmed.ncbi.nlm.nih.gov/27250948

Target-cell-specific short-term plasticity in local circuits

Autor: Txomin Lalanne, Rui Ponte Costa, Therese Abrahamsson, Arne V. Blackman, Per Jesper Sjöström

Publikováno v: Frontiers in Synaptic Neuroscience
Europe PubMed Central
Blackman, A V, Abrahamsson, T, Costa, R P, Lalanne, T & Sjöström, P J 2013, ' Target Cell-Specific Short-Term Plasticity in Local Circuits ', Frontiers in synaptic neuroscience, vol. 5, no. 11 . https://doi.org/10.3389/fnsyn.2013.00011
Frontiers in Synaptic Neuroscience, Vol 5 (2013)

Short-term plasticity (STP) denotes changes in synaptic strength that last up to tens of seconds. It is generally thought that STP impacts information transfer across synaptic connections and may thereby provide neurons with, for example, the ability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79eb69979ce7a5646f68cd5e8f83c1a0
http://europepmc.org/articles/PMC3854841