Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Therese Östberg"'
Autor:
Xintong Jiang, Susanna Brauner, Marie Wahren-Herlenius, Therese Östberg, Zhong-qun Yan, Anna M. Lundberg, Vijay K. Kuchroo, Göran K. Hansson, Gudny Ella Thorlacius
Publikováno v:
Cardiovascular research. 114(1)
AimsPatients with hyperlipidemia are at risk of atherosclerosis, but not all develop cardiovascular disease, highlighting the importance of other risk factors such as inflammation. Both the innate and adaptive arms of the immune system have been sugg
Autor:
Marco Bianchi, Sangeeta S. Chavan, Lena Klevenvall, Huan Yang, Shigekazu Nagata, Helena Erlandsson Harris, Ulf Andersson, Kohki Kawane, Therese Östberg, Karin Palmblad
Publikováno v:
Arthritis & Rheumatism. 62:2963-2972
Objective. High mobility group box chromosomal protein 1 (HMGB-1) is a DNA binding nuclear protein that can be released from dying cells and activated myeloid cells. Extracellularly, HMGB-1 promotes inflammation. Clinical and experimental studies dem
Autor:
Birgitta Glenmark, Helena Erlandsson-Harris, Ingrid E. Lundberg, Shi-Jin Zhang, Cecilia Grundtman, Natalia Kosterina, Takashi Yamada, Håkan Westerblad, Joseph D. Bruton, Therese Östberg, Nicolas Place
Publikováno v:
Arthritis & Rheumatism. 60:3280-3289
Progressive muscle weakness is a common feature in patients with rheumatoid arthritis (RA). However, little is known about whether the intrinsic contractile properties of muscle fibers are affected in RA. This study was undertaken to investigate musc
Autor:
Stina Salomonsson, Anders Hamsten, Sven-Erik Sonesson, Tomas Olsson, Fredrik Gadler, Ingrid Kockum, Anders Jonzon, Lars Alfredsson, Marie Wahren-Herlenius, Sabrina Meisgen, Tomas Axelsson, Therese Östberg, Lars Klareskog, Håkan Eliasson, Bo Ding, Anders Mälarstig
Publikováno v:
Journal of internal medicine. 275(6)
Objective The main aim of this study was to identify foetal susceptibility genes on chromosome six for Ro/SSA autoantibody-mediated congenital heart block. Subjects and Design Single nucleotide polymorphism (SNP) genotyping of individuals in the Swed
Autor:
David S. Pisetsky, Håkan Westerblad, Joseph D. Bruton, Ulf Andersson, Cecilia Grundtman, Helena Erlandsson Harris, Therese Östberg, Ingrid E. Lundberg, Takashi Yamada
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(2)
Idiopathic inflammatory myopathies (IIMs) are heterogeneous rheumatic disorders of unknown cause characterized by muscle weakness, inflammatory cell infiltrates, and major histocompatibility complex (MHC) class I expression on muscle fibers. The nonh
Autor:
Helena Erlandsson Harris, Hulda Sigridur Hreggvidsdottir, Ann-Charlotte Aveberger, Lars Ottosson, Lena Klevenvall, Hanna Schierbeck, Ulf Andersson, Heidi Wähämaa, Karin Palmblad, Therese Östberg
Publikováno v:
Journal of leukocyte biology. 86(3)
A prototypic mechanism for enhancement of inflammation by an endogenous molecule is described. The nuclear protein HMGB1 has previously been demonstrated to act as an alarmin and to promote inflammation upon extracellular release, yet its mode of act
Autor:
Weiwen Jiang, Ann-Charlotte Aveberger, Cecilia K Zetterström, Hanna Schierbeck, Heidi Wähämaa, David S. Pisetsky, Helena Erlandsson Harris, Therese Östberg, Michael T. Lotze, Ulf Andersson
Publikováno v:
Journal of leukocyte biology. 83(1)
Gold compounds such as gold sodium thiomalate (GST) can reduce the symptoms of rheumatoid arthritis (RA), although their mechanism of action is not well defined. As the proinflammatory mediator high mobility group box chromosomal protein 1 (HMGB1) ma
Autor:
Ulf Andersson, R. Kokkola, B. Arnold, P. Nawroth, Helena Erlandsson Harris, Therese Östberg, Åsa Andersson, Carl Johan Treutiger, Robert A. Harris, G. Mullins
Publikováno v:
Karolinska Institutet
High-mobility group box chromosomal protein 1 (HMGB1) is a protein with both intranuclear functions and extracellular cytokine-like effects. In this report, we study possible candidate receptors for HMGB1 on macrophages (Mphi) and define pathways act
Publikováno v:
Annals of the Rheumatic Diseases. 69:A36-A37
The endogenous, nuclear protein High Mobility Group Box chromosomal protein 1(HMGB1) is secreted by activated macrophages/monocytes and, once extracellular, promotes inflammation. Extracellular HMGB1 is present in the synovitis of patients with rheum
Autor:
Fredrik Gadler, Anders Hamsten, Anders Mälarstig, Anders Jonzon, Tomas Olsson, Bo Ding, Sven-Erik Sonesson, Sabrina Gorgen, Marie Wahren-Herlenius, Ingrid Kockum, Lars Alfredsson, Therese Östberg, Stina Salomonsson, Tomas Axelsson, Håkan Eliasson, Lars Klareskog
Publikováno v:
Annals of the Rheumatic Diseases. 72:A56.1-A56
Objective To identify foetal susceptibility genes in Ro/SSA autoantibody-mediated congenital heart block on chromosome six. Methods Single nucleotide polymorphism (SNP) genotyping of individuals included in the Swedish Congenital Heart Block (CHB) st