Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Therese, Törngren"'
Autor:
Anna Öfverholm, Therese Törngren, Anna Rosén, Brita Arver, Zakaria Einbeigi, Karin Haraldsson, Anne Kinhult Ståhlbom, Ekaterina Kuchinskaya, Annika Lindblom, Beatrice Melin, Ylva Paulsson-Karlsson, Marie Stenmark-Askmalm, Emma Tham, Anna von Wachenfeldt, Anders Kvist, Åke Borg, Hans Ehrencrona
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Genetic screening for pathogenic variants (PVs) in cancer predisposition genes can affect treatment strategies, risk prediction and preventive measures for patients and families. For decades, hereditary breast and ovarian cancer (
Externí odkaz:
https://doaj.org/article/14836a1cde9041ceac9a11aee8d70d95
Autor:
Nanna Bæk Møller, Desirée Sofie Boonen, Elisabeth Simone Feldner, Qin Hao, Martin Larsen, Anne-Vibeke Lænkholm, Åke Borg, Anders Kvist, Therese Törngren, Uffe Birk Jensen, Susanne Eriksen Boonen, Mads Thomassen, Thorkild Terkelsen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract BOADICEA is a comprehensive risk prediction model for breast and/or ovarian cancer (BC/OC) and for carrying pathogenic variants (PVs) in cancer susceptibility genes. In addition to BRCA1 and BRCA2, BOADICEA version 6 includes PALB2, CHEK2, A
Externí odkaz:
https://doaj.org/article/7720269c009548b3b95c0d2edd9d5c77
Autor:
Nanna Bæk Møller, Desirée Sofie Boonen, Elisabeth Simone Feldner, Qin Hao, Martin Larsen, Anne‑Vibeke Lænkholm, Åke Borg, Anders Kvist, Therese Törngren, Uffe Birk Jensen, Susanne Eriksen Boonen, Mads Thomassen, Thorkild Terkelsen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/f3f3aaf8eb464ea39a6defff1960603f
Autor:
Sandra Wessman, Beatriz Bohorquez Fuentes, Therese Törngren, Anders Kvist, Georgia Kokaraki, Hanna Menkens, Elisabet Hjerpe, Ythalo Hugo da Silva Santos, Tirzah Braz Petta, Åke Borg, Joseph W. Carlson
Publikováno v:
Cancers, Vol 13, Iss 20, p 5240 (2021)
Background: We examined whether molecular characterization of high-grade epithelial ovarian cancer can inform the diagnosis and/or identify potential actionable targets. Methods: All of the consecutively sequenced high-grade ovarian tumours with cons
Externí odkaz:
https://doaj.org/article/f3740347f5ba4797966eeec7bcc7f9bc
Autor:
Martin Lauss, Marco Donia, Katja Harbst, Rikke Andersen, Shamik Mitra, Frida Rosengren, Maryem Salim, Johan Vallon-Christersson, Therese Törngren, Anders Kvist, Markus Ringnér, Inge Marie Svane, Göran Jönsson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Adoptive T cell therapy (ACT) has yielded high response rates in melanoma, however 50–60% of patients experience no clinical benefit. Here, the authors identify predictive biomarkers, high non-synonymous mutation and high expressed neoantigen load,
Externí odkaz:
https://doaj.org/article/63635278846d435eabbeb4ee5d2c1d15
Supplementary Table 1 from Molecular Profiling Reveals Low- and High-Grade Forms of Primary Melanoma
Autor:
Göran Jönsson, Hensin Tsao, Åke Borg, Christian Ingvar, Håkan Olsson, Karin Jirström, Lotta Lundgren, Markus Ringnér, Mattias Höglund, Jürgen Geisler, Henrik Ekedahl, Therese Törngren, Johan Vallon-Christersson, Pär-Ola Bendahl, Iva Johansson, Anna Måsbäck, Anna Karlsson, Martin Lauss, Johan Staaf, Katja Harbst
PDF file - 51K, Univariate analyses in the whole cohort and in melanomas with a Breslow thickness > 2mm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffdb49ea2cf88652ac695e2665ceef9
https://doi.org/10.1158/1078-0432.22446413
https://doi.org/10.1158/1078-0432.22446413
Autor:
Göran Jönsson, Hensin Tsao, Åke Borg, Christian Ingvar, Håkan Olsson, Karin Jirström, Lotta Lundgren, Markus Ringnér, Mattias Höglund, Jürgen Geisler, Henrik Ekedahl, Therese Törngren, Johan Vallon-Christersson, Pär-Ola Bendahl, Iva Johansson, Anna Måsbäck, Anna Karlsson, Martin Lauss, Johan Staaf, Katja Harbst
Purpose: For primary melanomas, tumor thickness, mitotic rate, and ulceration are well-laid cornerstones of prognostication. However, a molecular exposition of melanoma aggressiveness is critically missing. We recently uncovered a four-class structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a21d730d6544295cdf6f352758570ce
https://doi.org/10.1158/1078-0432.c.6520745
https://doi.org/10.1158/1078-0432.c.6520745
Autor:
Göran Jönsson, Ana Carneiro, Christian Ingvar, Håkan Olsson, Åke Borg, Bo Baldetorp, Johan Vallon-Christersson, Maria C. Johansson, Anders Kvist, Therese Törngren, Frida Rosengren, Karolin Isaksson, Helena Cirenajwis, Martin Lauss, Katja Harbst
159930_1_supp_0_t72r9t.jpg from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4bcc4d29bca480eb1d475f91f53baf
https://doi.org/10.1158/0008-5472.22411715.v1
https://doi.org/10.1158/0008-5472.22411715.v1
Supplementary Table 2 from Molecular Profiling Reveals Low- and High-Grade Forms of Primary Melanoma
Autor:
Göran Jönsson, Hensin Tsao, Åke Borg, Christian Ingvar, Håkan Olsson, Karin Jirström, Lotta Lundgren, Markus Ringnér, Mattias Höglund, Jürgen Geisler, Henrik Ekedahl, Therese Törngren, Johan Vallon-Christersson, Pär-Ola Bendahl, Iva Johansson, Anna Måsbäck, Anna Karlsson, Martin Lauss, Johan Staaf, Katja Harbst
PDF file - 79K, Significant canonical pathways (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a369095f4b28b95e67cb6684d75325
https://doi.org/10.1158/1078-0432.22446410
https://doi.org/10.1158/1078-0432.22446410
Autor:
Göran Jönsson, Ana Carneiro, Christian Ingvar, Håkan Olsson, Åke Borg, Bo Baldetorp, Johan Vallon-Christersson, Maria C. Johansson, Anders Kvist, Therese Törngren, Frida Rosengren, Karolin Isaksson, Helena Cirenajwis, Martin Lauss, Katja Harbst
Overview of the study workflow (S1); Hematoxylin & eosin stainings of samples in the study (S2); FACS ploidy histogram of Mm1702 (S3); Mutation-plots demonstrating the subclonality analysis in different regions of tumor Mm1641 (S4); Mutation-plots de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b415a62a2f1d7be8662e8a5c0aac24
https://doi.org/10.1158/0008-5472.22411712
https://doi.org/10.1158/0008-5472.22411712