Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Theresa T. Pham"'
Autor:
William K. Schmidt, Irene Cortés‐Puch, Cindy B. McReynolds, Glenn E. Croston, Sung Hee Hwang, Jun Yang, Theresa L. Pedersen, Karen M. Wagner, Theresa T. Pham, Thomas Hunt, Bruce D. Hammock
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 9, Pp n/a-n/a (2024)
Abstract Chronic pain represents a significant unmet medical need, affecting one‐fifth of the U.S. population. EC5026 is a small molecule inhibitor of the enzyme soluble epoxide hydrolase (sEH) which is being developed as a novel non‐opioid, non
Externí odkaz:
https://doaj.org/article/d23ba464802241f69df3a0fdd283dc0d
Autor:
Max Lataillade, Lindsey Webster, Jianfeng Xu, Laurie Butcher, Eric Zimmerman, Samit R Joshi, Thomas J Greene, Theresa T. Pham, Mark Johnson, Teodora Pene Dumitrescu, Sherene Min
Publikováno v:
British Journal of Clinical Pharmacology
Aims GSK3640254, a novel, next-generation maturation inhibitor effective against a range of HIV polymorphisms with no cross-resistance to current antiretroviral therapy, could potentially be coadministered with dolutegravir as a 2-drug regimen. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7412ea199bc6682fd6c2c0cf76e6b0
https://doi.org/10.1111/bcp.14759
https://doi.org/10.1111/bcp.14759
Autor:
Theresa T. Pham, Allena J. Ji, Jyoti Sharma, Sebastiaan J.M. Gaemers, M. Judith Peterschmitt, Nigel P. S. Crawford
Publikováno v:
Clinical Pharmacology in Drug Development
Venglustat is a small‐molecule glucosylceramide synthase (GCS) inhibitor designed to reduce the production of glucosylceramide (GL‐1) and thus is expected to substantially reduce formation of glucosylceramide‐based glycosphingolipids. Because o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860129f2f4e029ab551b1a78f4bfbf7d
https://doi.org/10.1002/cpdd.865
https://doi.org/10.1002/cpdd.865
Autor:
Lindsey Webster, Sherene Min, Teodora Pene Dumitrescu, Eric Zimmerman, Max Lataillade, Thomas J Greene, Laurie Butcher, Fiona Halliday, Mark Johnson, Samit R Joshi, Theresa T. Pham, Jianfeng Xu
Publikováno v:
British journal of clinical pharmacology. 88(4)
Aims GSK3640254 is a next-generation maturation inhibitor likely to be coadministered with combined oral contraceptives in HIV-positive women. Methods This phase I, open-label, 1-way study assessed pharmacokinetic and pharmacodynamic interactions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd2edd4c6d3f25535472609005460ff
https://pubmed.ncbi.nlm.nih.gov/34427938
https://pubmed.ncbi.nlm.nih.gov/34427938
Publikováno v:
Clinical pharmacology in drug development. 5(3)
This study aimed to determine the impact of food on the pharmacokinetics of orteronel, an investigational nonsteroidal, reversible selective inhibitor of 17,20-lyase. In this open-label, randomized crossover study, healthy subjects received single do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03304326d785250448d0139422800154
https://pubmed.ncbi.nlm.nih.gov/27163497
https://pubmed.ncbi.nlm.nih.gov/27163497
Autor:
Schmidt, William K.1 (AUTHOR) schmidtwk@sbcglobal.net, Cortés‐Puch, Irene1 (AUTHOR), McReynolds, Cindy B.1 (AUTHOR), Croston, Glenn E.1 (AUTHOR), Hwang, Sung Hee1 (AUTHOR), Yang, Jun1 (AUTHOR), Pedersen, Theresa L.1 (AUTHOR), Wagner, Karen M.1 (AUTHOR), Pham, Theresa T.2 (AUTHOR), Hunt, Thomas2 (AUTHOR), Hammock, Bruce D.1 (AUTHOR)
Publikováno v:
CTS: Clinical & Translational Science. Sep2024, Vol. 17 Issue 9, p1-14. 14p.
Autor:
Peterschmitt, M. Judith1 (AUTHOR) Judith.Peterschmitt@sanofi.com, Crawford, Nigel P. S.2 (AUTHOR), Gaemers, Sebastiaan J. M.3 (AUTHOR), Ji, Allena J.4 (AUTHOR), Sharma, Jyoti2 (AUTHOR), Pham, Theresa T.5 (AUTHOR)
Publikováno v:
Clinical Pharmacology in Drug Development. Jan2021, Vol. 10 Issue 1, p86-98. 13p.
Publikováno v:
Pain & Central Nervous System Week; 10/7/2024, p2254-2254, 1p
Autor:
Pene Dumitrescu, Teodora, Greene, Thomas J., Joshi, Samit R., Xu, Jianfeng, Johnson, Mark, Halliday, Fiona, Butcher, Laurie, Zimmerman, Eric, Webster, Lindsey, Pham, Theresa T., Lataillade, Max, Min, Sherene
Publikováno v:
British Journal of Clinical Pharmacology; Apr2022, Vol. 88 Issue 4, p1704-1712, 9p
Autor:
Pene Dumitrescu, Teodora, Joshi, Samit R., Xu, Jianfeng, Greene, Thomas J., Johnson, Mark, Butcher, Laurie, Zimmerman, Eric, Webster, Lindsey, Pham, Theresa T., Lataillade, Max, Min, Sherene
Publikováno v:
British Journal of Clinical Pharmacology; Sep2021, Vol. 87 Issue 9, p3501-3507, 7p