Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Theresa R Cassino"'
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Cell development and behavior are driven by internal genetic programming, but the external microenvironment is increasingly recognized as a significant factor in cell differentiation, migration, and in the case of cancer, metastatic progression. Yet
Autor:
Shara D. Rice, Stacey L. Brower, Karl E Williams, Nan Song, Theresa R Cassino, Lahari Sakhamuri
Publikováno v:
Cancer Biology & Therapy. 11:196-203
Cetuximab is a chimeric monoclonal antibody for the epidermal growth factor receptor (EGFR) that may provide benefit to select cancer patients; however, identification of the characteristics of those patients who may benefit from its use is not compl
Publikováno v:
Small. 5:1984-1989
Molecular distribution within living cells is organized through multiscaled compartmentalization that enables specialized processes to occur with high efficiency. The ability to control the chemical environment at a subcellular level is limited due t
Autor:
Thomas E. Ryan, Luz Padro, Theresa R. Cassino, Manoj Gopalakrishnan, Uwe C. Täuber, Kimberly Forsten-Williams
Publikováno v:
European Biophysics Journal. 34:943-958
Rebinding of dissociated ligands from cell surface proteins can confound quantitative measurements of dissociation rates important for characterizing the affinity of binding interactions. This can be true also for in vitro techniques such as surface
Autor:
Masaho Okada, Lauren Drowley, Kimimasa Tobita, Sarah A. Beckman, Philip R. LeDuc, Bradley B. Keller, Johnny Huard, Theresa R. Cassino
Publikováno v:
Tissue engineering. Part A. 18(11-12)
Stem cell therapy for tissue repair is a rapidly evolving field and the factors that dictate the physiological responsiveness of stem cells remain under intense investigation. In this study we hypothesized that the mechanical loading history of muscl
Publikováno v:
ASME 2008 Summer Bioengineering Conference, Parts A and B.
Muscle-derived stem cells (MDSCs) have been successfully transplanted into both skeletal (1) and cardiac muscle (2) of dystrophin-deficient (mdx) mice, and show potential for improving cardiac and skeletal dysfunction in diseases like Duchenne muscul
Autor:
Diane K. Seamans, Brian J. Love, Roger J. Anderson, Kimberly Forsten-Williams, William R. Huckle, Theresa R. Cassino
Publikováno v:
Biotechnology and bioengineering. 98(1)
Mechanical compression has been shown to impact cell activity; however a need for a single device to perform a broader range of parametric studies exists. We have developed an oscillatory displacement controlled device to uniaxially strain cell const
Autor:
Johnny Huard, Lauren Drowley, Philip R. LeDuc, Joseph M. Feduska, Theresa R. Cassino, Masaho Okada
Publikováno v:
ASME 2007 Summer Bioengineering Conference.
Muscle-derived stem cell (MDSC) transplantation has shown potential as a therapy for cardiac and skeletal muscle dysfunction in diseases such as Duchenne muscular dystrophy (DMD). In this study we explore mechanical environment and its effects on MDS
Autor:
Theresa R. Cassino, Anne S. Robinson, Kimberly Forsten-Williams, Abigail D. Bellis, Thomas E. Ryan, Laura J. Delo
Publikováno v:
Journal of cellular physiology. 210(2)
The cellular microenvironment impacts how signals are transduced by cells and plays a key role in tissue homeostasis. Although pH is generally well regulated, there are a number of situations where acidosis occurs and our work addresses how low pH im
Publikováno v:
Clinical Cancer Research. 16:A31-A31
Background: The epidermal growth factor pathway is an important driver of cancer growth. Erlotinib is a small molecule protein-kinase inhibitor targeting the epidermal growth factor receptor (EGFR) that may benefit a select subtype of cancer patients