Výsledky vyhledávání - "Theresa Q. Phan"

DNA recognition by thyroid hormone and retinoic acid receptors: 3,4,5 rule modified

Autor: Margaret M. Jow, Martin L. Privalsky, Theresa Q. Phan

Publikováno v: Molecular and Cellular Endocrinology. 319:88-98

It has been proposed that retinoic acid receptors (RARs) and thyroid hormone receptors (TRs) both bind to AGGTCA “half-site” sequences, but distinguish their different target genes by recognizing different half-site spacings. We report here that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26887e34d784e2abf68be25bf1ff5966
https://doi.org/10.1016/j.mce.2009.11.010

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Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants

Autor: Theresa Q. Phan, Michael L. Goodson, Brenda J. Mengeling, Martin L. Privalsky

Publikováno v: The Journal of biological chemistry. 286(6)

Human acute promyelocytic leukemia is causally linked to chromosomal translocations that generate chimeric retinoic acid receptor-α proteins (x-RARα fusions). Wild-type RARα is a transcription factor that binds to the SMRT/NCoR family of corepress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b777af0d6f7b215e89cf796a5ee4f3
https://pubmed.ncbi.nlm.nih.gov/21131350

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