Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Theresa Pasqualini"'
Autor:
Sophia Gayle, Robert Aiello, Jane Bechtold, Patricia Bourassa, Johanna Csengery, Connor Hagen, Katia Howard, Kelli Jones, Lori Lopresti-Morrow, Robert Maguire, Timothy Paradis, Theresa Pasqualini, Joseph Tweed, Laurie Tylaska, Qing Zhang, Vishwas Paralkar
Publikováno v:
Cancer Research. 82:1764-1764
Auristatins such as monomethyl auristatin E (MMAE) are a class of high potency microtubule targeting compounds that have an extremely narrow therapeutic window. Targeting potent auristatins to the tumor is the only feasible method of unlocking the cl
Publikováno v:
The Journal of Experimental Medicine
Naive CD4+ T cells can differentiate into cells predominantly involved in humoral immunity, known as T helper type 2 cells (Th2), or cells involved in cell-mediated immunity, known as Th1 cells. In this report, we show that priming of CD4+ T cells be
Autor:
Theresa Pasqualini, Mona Zain, Kim Bottomly, Stephanie L. Constant, Patricia Ranney, Jeff West
Publikováno v:
European journal of immunology. 24(5)
Primed and unprimed lymphocytes are usually classified as separate subsets of cells, based on phenotypic and functional distinctions. In the case of CD4+ T lymphocytes, primed cells are thought to proliferate more vigorously, quickly and easily, and
Autor:
Theresa Pasqualini, Donal B. Murphy, Mohammad Luqman, Jeff West, Laurence Greenbaum, Simon R. Carding, Kim Bottomly
Publikováno v:
European journal of immunology. 19(4)
CD4 T cell clones have been shown to be functionally heterogeneous in the mouse. However, it is not known if normal CD4 T cells are also functionally heterogeneous, or whether functional specialization is a result of cloning and long-term culture. To