Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Theresa M. Kisko"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
BackgroundHealthy brain development depends on early social practices and experiences. The risk gene CACNA1C is implicated in numerous neuropsychiatric disorders, in which key characteristics include deficits in social functioning and communication.
Externí odkaz:
https://doaj.org/article/96b96acaaf6e43cd8c0c5f612a8553c6
Autor:
Susanne Michels, Amalia M. Dolga, Moria D. Braun, Theresa M. Kisko, A. Özge Sungur, Stephanie H. Witt, Marcella Rietschel, Astrid Dempfle, Markus Wöhr, Rainer K. W. Schwarting, Carsten Culmsee
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The pathophysiology of neuropsychiatric disorders involves complex interactions between genetic and environmental risk factors. Confirmed by several genome-wide association studies, Cacna1c represents one of the most robustly replicated psychiatric r
Externí odkaz:
https://doaj.org/article/1c8a420191c34eb09b4cd223c800c049
Publikováno v:
Brain Sciences, Vol 11, Iss 6, p 724 (2021)
The top-ranked cross-disorder risk gene CACNA1C is strongly associated with multiple neuropsychiatric dysfunctions. In a recent series of studies, we applied a genomically informed approach and contributed extensively to the behavioral characterizati
Externí odkaz:
https://doaj.org/article/1cb29a6fc8db4837ad5aba3c7636ee9a
Autor:
Theresa M. Kisko, Moria D. Braun, Susanne Michels, Stephanie H. Witt, Marcella Rietschel, Carsten Culmsee, Rainer K. W. Schwarting, Markus Wöhr
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 6 (2018)
The cross-disorder risk gene CACNA1C is strongly implicated in multiple neuropsychiatric disorders, including autism spectrum disorder (ASD), bipolar disorder (BPD) and schizophrenia (SCZ), with deficits in social functioning being common for all maj
Externí odkaz:
https://doaj.org/article/7c48702c522b463a9200d23aea0e95a8
Autor:
Kockskämper, Hauke Fender, Kim Walter, Aytug K. Kiper, Jelena Plačkić, Theresa M. Kisko, Moria D. Braun, Rainer K. W. Schwarting, Susanne Rohrbach, Markus Wöhr, Niels Decher, Jens
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9795
CACNA1C encodes the pore-forming α1C subunit of the L-type Ca2+ channel, Cav1.2. Mutations and polymorphisms of the gene are associated with neuropsychiatric and cardiac disease. Haploinsufficient Cacna1c+/− rats represent a recently developed mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0273897fa27149038c8f7ab55c35a751
Publikováno v:
Behavioural Brain Research. 367:35-52
The risk gene CACNA1C is strongly implicated in the etiology of all major psychiatric disorders, such as depressive disorder, bipolar disorder, autism spectrum disorder, and schizophrenia. These disorders feature high levels of comorbidity and share
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9096a415521702cbcddc88874eb849a
https://doi.org/10.1016/j.bbr.2019.03.032
https://doi.org/10.1016/j.bbr.2019.03.032
Publikováno v:
Kisko, T M, Schwarting, R K W & Wöhr, M 2021, ' Sex differences in the acoustic features of social play-induced 50-kHz ultrasonic vocalizations : A detailed spectrographic analysis in wild-type Sprague–Dawley and Cacna1c haploinsufficient rats ', Developmental Psychobiology, vol. 63, no. 2, pp. 262-276 . https://doi.org/10.1002/dev.21998
Sexual dimorphisms are widespread in the animal kingdom. At the behavioral level, there is evidence for sex differences in social play behavior. In rats, males typically engage more in rough-and-tumble play than females. One prominent component of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c2ea8f73e2d5ad7b8669eadb90db83
https://lirias.kuleuven.be/handle/20.500.12942/687998
https://lirias.kuleuven.be/handle/20.500.12942/687998
Publikováno v:
Redecker, T M, Kisko, T M, Wöhr, M & Schwarting, R K W 2020, ' Cacna1c haploinsufficiency lacks effects on adult hippocampal neurogenesis and volumetric properties of prefrontal cortex and hippocampus in female rats ', Physiology and Behavior, vol. 223, 112974 . https://doi.org/10.1016/j.physbeh.2020.112974
The cross-disorder risk gene CACNA1C is strongly involved in the etiology of all major neuropsychiatric disorders, with women often being more affected by CACNA1C mutations than men. Human neuroimaging studies provided evidence that CACNA1C variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350f90635b3dedf9744cb9d8e9d750e9
https://pubmed.ncbi.nlm.nih.gov/32473156
https://pubmed.ncbi.nlm.nih.gov/32473156
Autor:
Theresa M. Kisko, Markus Wöhr, Débora Dalla Vecchia, Rainer K.W. Schwarting, Moria D. Braun, Roberto Andreatini
Publikováno v:
Neurobiology of Learning and Memory. 155:543-555
The CACNA1C gene is strongly implicated in the etiology of multiple major neuropsychiatric disorders, such as bipolar disorder, major depression, and schizophrenia, with cognitive deficits being a common feature. It is unclear, however, by which mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1120f417d7ba1890e5fc9ac7bb5bcc1
https://doi.org/10.1016/j.nlm.2018.05.012
https://doi.org/10.1016/j.nlm.2018.05.012
Publikováno v:
Animal Behaviour. 140:81-92
Play fighting in juvenile rats is associated with a high occurrence of 50 kHz vocalizations. These calls are varied in form, ranging from long, flat calls to short, frequency-modulated ones. We hypothesize that at least some types of calls serve as p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffdfe5c80f778cf803e96905ce026a16
https://doi.org/10.1016/j.anbehav.2018.03.019
https://doi.org/10.1016/j.anbehav.2018.03.019