Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Theresa M Thole"'
Autor:
Danny Jazmati, Barbara Hero, Theresa M. Thole.-Kliesch, Julien Merta, Hedwig E. Deubzer, Christian Bäumer, Feline Heinzelmann, Stefanie Schulze Schleithoff, Friederike Koerber, Angelika Eggert, Rudolf Schwarz, Thorsten Simon, Beate Timmermann
Publikováno v:
Current Oncology, Vol 29, Iss 11, Pp 8222-8234 (2022)
Background: Despite an intensive multimodal treatment approach, approximately 50% of high-risk (HR) neuroblastoma (NB) patients experience progression. Despite the advances in targeted therapy, high-dose chemotherapy, and other systemic treatment opt
Externí odkaz:
https://doaj.org/article/2eda78254f904a3a9f743eb2d70d7c1b
Autor:
Michael Launspach, Marita Seif, Theresa M. Thole, Patrick Jesse, Joachim Schulz, Johannes H. Schulte, Susan Bischoff, Angelika Eggert, Hedwig E. Deubzer
Publikováno v:
Children, Vol 8, Iss 2, p 91 (2021)
Extravasation can present serious accidental complication of intravenous drug application. While monoclonal antibodies do not show the necrotic potential of cytotoxic chemotherapy drugs, considerable inflammatory toxicity can occur, necessitating sta
Externí odkaz:
https://doaj.org/article/b099df494f7d4123bc10da52921beae6
Autor:
Hedwig E. Deubzer, Angelika Eggert, Holger Amthauer, Cornelia Eckert, Patrick Hundsdörfer, Johannes H. Schulte, Annabell Szymansky, Jörg Fuchs, Georg Schwabe, Lena Oevermann, Annette Künkele, Erwin Lankes, Jan F. Hollander, Rasmus B. Linke, Constantin Peitz, Maddalena Grimaldi, Annika Sprüssel, Kathy Astrahantseff, Theresa M. Thole-Kliesch, Josefine Graef, Marco Lodrini
Supplementary Figure from Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023bc1f15b2e0ed698b22e7742b1794c
https://doi.org/10.1158/1078-0432.22486932.v1
https://doi.org/10.1158/1078-0432.22486932.v1
Autor:
Hedwig E. Deubzer, Angelika Eggert, Holger Amthauer, Cornelia Eckert, Patrick Hundsdörfer, Johannes H. Schulte, Annabell Szymansky, Jörg Fuchs, Georg Schwabe, Lena Oevermann, Annette Künkele, Erwin Lankes, Jan F. Hollander, Rasmus B. Linke, Constantin Peitz, Maddalena Grimaldi, Annika Sprüssel, Kathy Astrahantseff, Theresa M. Thole-Kliesch, Josefine Graef, Marco Lodrini
Supplementary Data from Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff5da5f034c758093de815f467b900b
https://doi.org/10.1158/1078-0432.22486950.v1
https://doi.org/10.1158/1078-0432.22486950.v1
Autor:
Hedwig E. Deubzer, Angelika Eggert, Holger Amthauer, Cornelia Eckert, Patrick Hundsdörfer, Johannes H. Schulte, Annabell Szymansky, Jörg Fuchs, Georg Schwabe, Lena Oevermann, Annette Künkele, Erwin Lankes, Jan F. Hollander, Rasmus B. Linke, Constantin Peitz, Maddalena Grimaldi, Annika Sprüssel, Kathy Astrahantseff, Theresa M. Thole-Kliesch, Josefine Graef, Marco Lodrini
Purpose:Treating refractory or relapsed neuroblastoma remains challenging. Monitoring body fluids for tumor-derived molecular information indicating minimal residual disease supports more frequent diagnostic surveillance and may have the power to det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55434bc554f96e59046df70714a3d7e2
https://doi.org/10.1158/1078-0432.c.6532422
https://doi.org/10.1158/1078-0432.c.6532422
Autor:
Marco Lodrini, Jasmin Wünschel, Theresa M. Thole-Kliesch, Maddalena Grimaldi, Annika Sprüssel, Rasmus B. Linke, Jan F. Hollander, Daniela Tiburtius, Annette Künkele, Johannes H. Schulte, Erwin Lankes, Thomas Elgeti, Patrick Hundsdörfer, Kathy Astrahantseff, Thorsten Simon, Angelika Eggert, Hedwig E. Deubzer
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2080
Liquid biopsy strategies in pediatric patients are challenging due to low body weight. This study investigated cfDNA size distribution and concentration in blood, bone marrow, cerebrospinal fluid, and urine from 84 patients with neuroblastoma classif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8b1ea7fd9f5e2e53f08670b0791776
Autor:
Marco Lodrini, Josefine Graef, Theresa M. Thole-Kliesch, Kathy Astrahantseff, Annika Sprüssel, Maddalena Grimaldi, Constantin Peitz, Rasmus B. Linke, Jan F. Hollander, Erwin Lankes, Annette Künkele, Lena Oevermann, Georg Schwabe, Jörg Fuchs, Annabell Szymansky, Johannes H. Schulte, Patrick Hundsdörfer, Cornelia Eckert, Holger Amthauer, Angelika Eggert, Hedwig E. Deubzer
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 28(9)
Purpose: Treating refractory or relapsed neuroblastoma remains challenging. Monitoring body fluids for tumor-derived molecular information indicating minimal residual disease supports more frequent diagnostic surveillance and may have the power to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56db288827e8c2dbbcf2e4f922b124d2
https://pubmed.ncbi.nlm.nih.gov/35247920
https://pubmed.ncbi.nlm.nih.gov/35247920
Autor:
Eric Blanc, Annika Winkler, F Hertwig, Katharina Kasack, Joern Toedling, Filippos Klironomos, Victor Bardinet, Konstantin Helmsauer, Johannes H. Schulte, Anton G. Henssen, Patrick Hundsdörfer, Theresa M Thole, Natalie Timme, Ian C. MacArthur, Richard Koche, David Torrents, Elias Rodriguez-Fos, Nina Thiessen, Claudia Röefzaad, Montserrat Puiggròs, Hedwig E. Deubzer, Jessica Theissen, Karin Schmelz, Dieter Beule, Roland F. Schwarz, Carolina Rosswog, Steffen Fuchs, Rocio Chamorro, Annette Künkele, Angelika Eggert, Heathcliff Dorado Garcia, Sascha Sauer, Martin Burkert, Annabell Szymansky, Jesper L.V. Maag, Natalia Munoz-Perez, Matthias Fischer, Yi Bei
Publikováno v:
Nat Genet
Extrachromosomal circularization of DNA is an important genomic feature in cancer. The structure, composition and genome-wide frequency of extrachromosomal circular DNA, however, have not yet been extensively profiled. Here, we combined genomic and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87775e81c435286f7bad0fc82ccfe777
https://doi.org/10.1038/s41588-019-0547-z
https://doi.org/10.1038/s41588-019-0547-z
Autor:
Marco Lodrini, Joern Toedling, Dieter Beule, Annette Künkele, Anton G. Henssen, Theresa M Thole, Guido Gambara, Stefanie Groeneveld-Krentz, Johannes H. Schulte, Christian R A Regenbrecht, Cornelia Eckert, Hedwig E. Deubzer, Clemens Messerschmidt, Larissa Savelyeva, Annika Sprüssel, Angelika Eggert, Sabine Finkler, Sebastian Pfeil, Anja Sieber, Nils Bluethgen, David Capper
Publikováno v:
International journal of cancerReferences. 146(4)
Accurate modeling of intratumor heterogeneity presents a bottleneck against drug testing. Flexibility in a preclinical platform is also desirable to support assessment of different endpoints. We established the model system, OHC-NB1, from a bone marr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5564b5c52de339f2fd65cf19258570a6
https://pubmed.ncbi.nlm.nih.gov/31304977
https://pubmed.ncbi.nlm.nih.gov/31304977
Autor:
Joern Toedling, Victor Bardinet, Angelika Eggert, Carolina Rosswog, Natalia Munoz-Perez, Steffen Fuchs, Anton G. Henssen, Jesper L.V. Maag, Theresa M Thole, Johannes H. Schulte, Dieter Beule, Matthias Fischer, David Torrents, Filippos Klironomos, Heathcliff Dorado Garcia, Hedwig E. Deubzer, Annabell Szymansky, Montserrat Puiggròs, Natalie Timme, Ian C. MacArthur, Eric Blanc, Annika Winkler, Rocio Chamorro, Annette Künkele, F Hertwig, Karin Schmelz, Yi Bei, Roland F. Schwarz, Katharina Kasack, Richard Koche, Martin Burkert, Sascha Sauer, Patrick Hundsdörfer, Elias Rodriguez-Fos, Nina Thiessen, Jessica Theissen, Claudia Röefzaad, Konstantin Helmsauer
Publikováno v:
Nature Genetics. 52:464-464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c45bf3ca27715366109c9c9d09122e71
https://doi.org/10.1038/s41588-020-0598-1
https://doi.org/10.1038/s41588-020-0598-1